BiGG Models

Reaction: DHFR

Descriptive name:

Dihydrofolate reductase

Model:

Reaction:

dhf_c + h_c + nadph_c ⇌ nadp_c + thf_c

Metabolites:

Stoichiometry

BiGG ID

Name

7,8-Dihydrofolate

Nicotinamide adenine dinucleotide phosphate

Nicotinamide adenine dinucleotide phosphate - reduced

5,6,7,8-Tetrahydrofolate

Default bounds:

(-1000.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Cofactor and Prosthetic Group Biosynthesis

Gene Reaction Rule:

EC042_1774 or EC042_0050

Genes:

EC042_0050 (folA)
EC042_1774

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Universal reaction ?

DHFR

External database links

MetaNetX (MNX) Equation: MNXR97401
RHEA: 15009, 15010, 15011, 15012
EC Number: 1.5.1.3
KEGG Reaction: R00939
Reactome Reaction: R-BTA-197972, R-CEL-197972, R-CFA-197972, R-DDI-197972, R-DME-197972, R-DRE-197972, R-GGA-197972, R-HSA-197972, R-MMU-197972, R-RNO-197972, R-SCE-197972, R-SPO-197972, R-SSC-197972, R-TGU-197972, R-XTR-197972

Provided by MetaNetX (CC BY 4.0)

Old identifiers

DHFR

DHFR in other models