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Reaction: AM1CCShr

Descriptive name:

Oxidation of cyclosporine to AM1c in hepatocytes

Model:

Recon3D

Reaction:

h_r + nadph_r + o2_r + csa_r → h2o_r + nadp_r + am1ccs_r

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
h2o_r
H2O H2O
-1.0
h_r
H+
1.0
nadp_r
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_r
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
o2_r
O2 O2
1.0
am1ccs_r
AM1c (cyclosporine)
-1.0
csa_r
Cyclosporine

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

Genes:

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Universal reaction ?

External database links

Old identifiers

    AM1CCShr

AM1CCShr in other models