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Universal reaction: LVSTOXD3Hhep

Descriptive name:

Oxidation of lovastatin to 3-hydroxy-lovastatin in hepatocytes

Reaction:

h_r + nadph_r + o2_r + lvst_r ⇌ h2o_r + nadp_r + 3hlvst_r

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
h2o_r
H2O H2O
-1.0
h_r
H+
1.0
nadp_r
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_r
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
o2_r
O2 O2
-1.0
lvst_r
Lovastatin lactone form
1.0
3hlvst_r
3''-hydroxy-lovastatin lactone form

LVSTOXD3Hhep in BiGG models:

Organism
Model
Homo sapiens
Recon3D

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External database links

Old identifiers

    LVSTOXD3Hhep