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"h_c":-1.0, "nadp_c":1.0, "nadph_c":-1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"645_AT1 or 644_AT1", "subsystem":"Heme degradation", "notes":{ "original_bigg_ids":[ "BILIRED" ] }, "annotation":{ "bigg.reaction":[ "BILIRED" ], "ec-code":[ "1.3.1.24" ], "kegg.reaction":[ "R02393" ], "metanetx.reaction":[ "MNXR96259" ], "reactome.reaction":[ "R-GGA-189384", "R-DRE-189384", "R-HSA-189384", "R-MMU-189384", "R-XTR-189384", "R-DME-189384", "R-SSC-189384", "R-RNO-189384", "R-CFA-189384", "R-BTA-189384", "R-TGU-189384" ], "rhea":[ "15794", "15795", "15796", "15793" ], "sabiork":[ "2334" ], "sbo":"SBO:0000176", "seed.reaction":[ "rxn01723" ] } }, { "id":"EX_6htststerone_e", "name":"6 beta hydroxy testosterone exchange", "metabolites":{ "6htststerone_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_6htststerone[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_6htststerone_e" ], "metanetx.reaction":[ "MNXR95098" ], "sbo":"SBO:0000627" } }, { "id":"ATPasel_1", "name":"V-Type ATPase, H+ Transporting, Lysosomal", "metabolites":{ "adp_c":1.0, "atp_c":-1.0, "h2o_c":-1.0, "h_l":1.0, "pi_c":1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"((50617_AT1 and 533_AT1 and 527_AT1 and 8992_AT1 and 245972_AT1) or (50617_AT1 and 533_AT1 and 527_AT1 and 8992_AT1 and 9114_AT1) or (533_AT1 and 527_AT1 and 8992_AT1 and 535_AT1 and 245972_AT1) or (533_AT1 and 527_AT1 and 8992_AT1 and 535_AT1 and 9114_AT1) or (533_AT1 and 527_AT1 and 8992_AT1 and 50617_AT3 and 245972_AT1) or (533_AT1 and 527_AT1 and 8992_AT1 and 10312_AT1 and 9114_AT1) or (533_AT1 and 527_AT1 and 8992_AT1 and 245972_AT1 and 50617_AT2) or (533_AT1 and 527_AT1 and 8992_AT1 and 9114_AT1 and 23545_AT1) or (533_AT1 and 527_AT1 and 8992_AT1 and 10312_AT2 and 245972_AT1) or (533_AT1 and 527_AT1 and 8992_AT1 and 50617_AT3 and 9114_AT1) or (533_AT1 and 527_AT1 and 8992_AT1 and 245972_AT1 and 23545_AT1) or (533_AT1 and 527_AT1 and 8992_AT1 and 9114_AT1 and 50617_AT2) or (533_AT1 and 527_AT1 and 8992_AT1 and 10312_AT1 and 245972_AT1) or (533_AT1 and 527_AT1 and 8992_AT1 and 10312_AT2 and 9114_AT1)) and ((51382_AT1 and 9296_AT1 and 529_AT1 and 245973_AT1 and 523_AT1 and 51606_AT1 and 9550_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 127124_AT1 and 245973_AT1 and 525_AT1 and 90423_AT1 and 51606_AT2 and 523_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 534_AT2 and 90423_AT1 and 523_AT1 and 526_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 245973_AT1 and 534_AT2 and 523_AT1 and 90423_AT1 and 51606_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 534_AT1 and 51606_AT2 and 529_AT1 and 528_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 534_AT1 and 529_AT1 and 523_AT1 and 528_AT2 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 127124_AT1 and 529_AT1 and 525_AT1 and 523_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 245973_AT1 and 90423_AT1 and 127124_AT2 and 51606_AT2 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 127124_AT1 and 529_AT1 and 525_AT1 and 523_AT1 and 51606_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 529_AT1 and 245973_AT1 and 534_AT2 and 525_AT1 and 523_AT1) or (51382_AT1 and 9296_AT1 and 534_AT1 and 528_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 523_AT1 and 90423_AT1 and 9550_AT1 and 528_AT2 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 534_AT1 and 245973_AT1 and 525_AT1 and 90423_AT1 and 523_AT1) or (51382_AT1 and 9296_AT1 and 534_AT1 and 525_AT1 and 529_AT1 and 528_AT1 and 523_AT1 and 51606_AT1) or (51382_AT1 and 9296_AT1 and 90423_AT1 and 127124_AT2 and 51606_AT2 and 523_AT1 and 526_AT1 and 528_AT2) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 534_AT1 and 90423_AT1 and 528_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 529_AT1 and 525_AT1 and 523_AT1 and 127124_AT2 and 528_AT2) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 534_AT1 and 529_AT1 and 528_AT1 and 525_AT1 and 523_AT1) or (51382_AT1 and 9296_AT1 and 529_AT1 and 523_AT1 and 51606_AT1 and 127124_AT2 and 528_AT2 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 534_AT2 and 525_AT1 and 90423_AT1 and 528_AT1 and 523_AT1) or (51382_AT1 and 9296_AT1 and 534_AT2 and 90423_AT1 and 51606_AT2 and 523_AT1 and 526_AT1 and 528_AT2) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 525_AT1 and 523_AT1 and 90423_AT1 and 9550_AT1 and 528_AT2) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 534_AT1 and 525_AT1 and 90423_AT1 and 528_AT1 and 523_AT1) or (51382_AT1 and 9296_AT1 and 127124_AT1 and 245973_AT1 and 525_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1) or (51382_AT1 and 9296_AT1 and 245973_AT1 and 525_AT1 and 90423_AT1 and 127124_AT2 and 51606_AT2 and 523_AT1) or (51382_AT1 and 9296_AT1 and 534_AT1 and 525_AT1 and 51606_AT2 and 529_AT1 and 523_AT1 and 528_AT2) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 127124_AT1 and 529_AT1 and 528_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 127124_AT1 and 90423_AT1 and 523_AT1 and 526_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 127124_AT1 and 529_AT1 and 523_AT1 and 51606_AT1 and 528_AT2 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 525_AT1 and 90423_AT1 and 127124_AT2 and 528_AT1 and 523_AT1) or (51382_AT1 and 9296_AT1 and 90423_AT1 and 127124_AT2 and 51606_AT2 and 528_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 245973_AT1 and 534_AT2 and 525_AT1 and 90423_AT1 and 51606_AT2 and 523_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 127124_AT1 and 529_AT1 and 245973_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 245973_AT1 and 523_AT1 and 90423_AT1 and 9550_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 528_AT1 and 534_AT2 and 523_AT1 and 90423_AT1 and 51606_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 127124_AT1 and 525_AT1 and 90423_AT1 and 51606_AT2 and 528_AT1 and 523_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 529_AT1 and 534_AT2 and 525_AT1 and 523_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 127124_AT1 and 529_AT1 and 245973_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 529_AT1 and 528_AT1 and 523_AT1 and 127124_AT2 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 534_AT2 and 90423_AT1 and 528_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 534_AT1 and 51606_AT2 and 529_AT1 and 523_AT1 and 526_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 534_AT2 and 529_AT1 and 528_AT1 and 523_AT1 and 51606_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 534_AT1 and 90423_AT1 and 51606_AT2 and 523_AT1 and 526_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 127124_AT1 and 529_AT1 and 528_AT1 and 523_AT1 and 51606_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 127124_AT1 and 90423_AT1 and 51606_AT2 and 528_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 529_AT1 and 528_AT1 and 523_AT1 and 51606_AT1 and 9550_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 534_AT2 and 525_AT1 and 51606_AT2 and 529_AT1 and 528_AT1 and 523_AT1) or (51382_AT1 and 9296_AT1 and 529_AT1 and 245973_AT1 and 523_AT1 and 51606_AT1 and 127124_AT2 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 529_AT1 and 245973_AT1 and 523_AT1 and 9550_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 127124_AT1 and 525_AT1 and 90423_AT1 and 51606_AT2 and 523_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 127124_AT1 and 529_AT1 and 525_AT1 and 523_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 529_AT1 and 523_AT1 and 127124_AT2 and 528_AT2 and 526_AT1) or (51382_AT1 and 9296_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 9550_AT1 and 528_AT2 and 526_AT1) or (51382_AT1 and 9296_AT1 and 534_AT1 and 525_AT1 and 90423_AT1 and 51606_AT2 and 528_AT1 and 523_AT1) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 127124_AT1 and 529_AT1 and 528_AT1 and 525_AT1 and 523_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 529_AT1 and 245973_AT1 and 534_AT2 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 534_AT2 and 525_AT1 and 51606_AT2 and 529_AT1 and 523_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 245973_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 9550_AT1 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 529_AT1 and 528_AT1 and 523_AT1 and 9550_AT1 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 525_AT1 and 127124_AT2 and 529_AT1 and 528_AT1 and 523_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 528_AT1 and 525_AT1 and 523_AT1 and 90423_AT1 and 9550_AT1) or (51382_AT1 and 9296_AT1 and 529_AT1 and 245973_AT1 and 525_AT1 and 523_AT1 and 51606_AT1 and 127124_AT2) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 534_AT1 and 525_AT1 and 90423_AT1 and 523_AT1 and 528_AT2) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 245973_AT1 and 525_AT1 and 523_AT1 and 90423_AT1 and 9550_AT1) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 529_AT1 and 245973_AT1 and 523_AT1 and 127124_AT2 and 526_AT1) or (51382_AT1 and 9296_AT1 and 245973_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 127124_AT2 and 526_AT1) or (51382_AT1 and 9296_AT1 and 534_AT2 and 51606_AT2 and 529_AT1 and 523_AT1 and 526_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 534_AT1 and 51606_AT2 and 529_AT1 and 245973_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 127124_AT1 and 245973_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 529_AT1 and 528_AT1 and 523_AT1 and 51606_AT1 and 127124_AT2 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 127124_AT1 and 525_AT1 and 90423_AT1 and 528_AT1 and 523_AT1) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 245973_AT1 and 525_AT1 and 523_AT1 and 90423_AT1 and 9550_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 90423_AT1 and 127124_AT2 and 523_AT1 and 526_AT1 and 528_AT2) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 245973_AT1 and 90423_AT1 and 127124_AT2 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 525_AT1 and 9550_AT1 and 51606_AT2 and 529_AT1 and 528_AT1 and 523_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 529_AT1 and 528_AT1 and 525_AT1 and 523_AT1 and 9550_AT1) or (51382_AT1 and 9296_AT1 and 534_AT1 and 525_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 127124_AT1 and 529_AT1 and 245973_AT1 and 525_AT1 and 523_AT1) or (51382_AT1 and 9296_AT1 and 525_AT1 and 9550_AT1 and 51606_AT2 and 529_AT1 and 523_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 9550_AT1 and 51606_AT2 and 529_AT1 and 523_AT1 and 526_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 529_AT1 and 245973_AT1 and 525_AT1 and 523_AT1 and 51606_AT1 and 9550_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 534_AT1 and 245973_AT1 and 90423_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 529_AT1 and 245973_AT1 and 534_AT2 and 525_AT1 and 523_AT1 and 51606_AT1) or (51382_AT1 and 9296_AT1 and 525_AT1 and 90423_AT1 and 127124_AT2 and 51606_AT2 and 523_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 525_AT1 and 127124_AT2 and 529_AT1 and 528_AT1 and 523_AT1 and 51606_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 127124_AT1 and 245973_AT1 and 525_AT1 and 90423_AT1 and 523_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 529_AT1 and 525_AT1 and 523_AT1 and 127124_AT2 and 528_AT2) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 127124_AT1 and 90423_AT1 and 528_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 529_AT1 and 525_AT1 and 523_AT1 and 51606_AT1 and 9550_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 534_AT1 and 245973_AT1 and 525_AT1 and 90423_AT1 and 51606_AT2 and 523_AT1) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 529_AT1 and 528_AT1 and 523_AT1 and 127124_AT2 and 526_AT1) or (51382_AT1 and 9296_AT1 and 245973_AT1 and 534_AT2 and 90423_AT1 and 51606_AT2 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 534_AT2 and 525_AT1 and 90423_AT1 and 51606_AT2 and 523_AT1 and 528_AT2) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 529_AT1 and 523_AT1 and 9550_AT1 and 528_AT2 and 526_AT1) or (51382_AT1 and 9296_AT1 and 534_AT2 and 525_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 534_AT1 and 525_AT1 and 51606_AT2 and 529_AT1 and 528_AT1 and 523_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 534_AT1 and 529_AT1 and 528_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 534_AT2 and 51606_AT2 and 529_AT1 and 528_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 127124_AT1 and 528_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 127124_AT1 and 529_AT1 and 523_AT1 and 528_AT2 and 526_AT1) or (51382_AT1 and 9296_AT1 and 534_AT1 and 245973_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 127124_AT1 and 90423_AT1 and 51606_AT2 and 523_AT1 and 526_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 534_AT2 and 529_AT1 and 523_AT1 and 51606_AT1 and 526_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 534_AT1 and 525_AT1 and 529_AT1 and 523_AT1 and 51606_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 245973_AT1 and 523_AT1 and 90423_AT1 and 9550_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 127124_AT1 and 528_AT1 and 525_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 534_AT2 and 525_AT1 and 90423_AT1 and 523_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 127124_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 528_AT2 and 526_AT1) or (51382_AT1 and 9296_AT1 and 127124_AT1 and 529_AT1 and 528_AT1 and 525_AT1 and 523_AT1 and 51606_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 127124_AT1 and 529_AT1 and 245973_AT1 and 525_AT1 and 523_AT1) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 127124_AT1 and 529_AT1 and 523_AT1 and 528_AT2 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 534_AT1 and 90423_AT1 and 523_AT1 and 526_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 525_AT1 and 523_AT1 and 90423_AT1 and 9550_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 127124_AT1 and 529_AT1 and 528_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 529_AT1 and 245973_AT1 and 534_AT2 and 523_AT1 and 51606_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 528_AT1 and 534_AT2 and 525_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 127124_AT1 and 245973_AT1 and 90423_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 529_AT1 and 245973_AT1 and 525_AT1 and 523_AT1 and 127124_AT2) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 529_AT1 and 245973_AT1 and 525_AT1 and 523_AT1 and 9550_AT1) or (51382_AT1 and 9296_AT1 and 528_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 127124_AT2 and 526_AT1) or (51382_AT1 and 9296_AT1 and 529_AT1 and 523_AT1 and 51606_AT1 and 9550_AT1 and 528_AT2 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 534_AT1 and 529_AT1 and 525_AT1 and 523_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 534_AT1 and 51606_AT2 and 529_AT1 and 245973_AT1 and 525_AT1 and 523_AT1) or (51382_AT1 and 9296_AT1 and 528_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 9550_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 525_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 9550_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 534_AT1 and 90423_AT1 and 51606_AT2 and 528_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 529_AT1 and 245973_AT1 and 534_AT2 and 525_AT1 and 523_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 90423_AT1 and 127124_AT2 and 528_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 529_AT1 and 525_AT1 and 523_AT1 and 51606_AT1 and 127124_AT2 and 528_AT2) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 528_AT1 and 523_AT1 and 90423_AT1 and 9550_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 534_AT1 and 529_AT1 and 528_AT1 and 523_AT1 and 51606_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 9550_AT1 and 51606_AT2 and 529_AT1 and 528_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 529_AT1 and 528_AT1 and 534_AT2 and 525_AT1 and 523_AT1) or (51382_AT1 and 9296_AT1 and 127124_AT1 and 525_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 127124_AT1 and 529_AT1 and 245973_AT1 and 523_AT1 and 51606_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 534_AT2 and 523_AT1 and 90423_AT1 and 51606_AT1 and 528_AT2 and 526_AT1) or (51382_AT1 and 9296_AT1 and 534_AT1 and 245973_AT1 and 90423_AT1 and 51606_AT2 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 528_AT1 and 525_AT1 and 523_AT1 and 90423_AT1 and 9550_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 529_AT1 and 245973_AT1 and 523_AT1 and 127124_AT2 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 245973_AT1 and 534_AT2 and 525_AT1 and 90423_AT1 and 523_AT1) or (51382_AT1 and 9296_AT1 and 534_AT1 and 529_AT1 and 523_AT1 and 51606_AT1 and 526_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 534_AT1 and 245973_AT1 and 525_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 529_AT1 and 245973_AT1 and 523_AT1 and 9550_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 245973_AT1 and 534_AT2 and 525_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 245973_AT1 and 534_AT2 and 90423_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 525_AT1 and 90423_AT1 and 127124_AT2 and 51606_AT2 and 528_AT1 and 523_AT1) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 529_AT1 and 245973_AT1 and 534_AT2 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 534_AT1 and 529_AT1 and 245973_AT1 and 525_AT1 and 523_AT1 and 51606_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 529_AT1 and 528_AT1 and 534_AT2 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 523_AT1 and 90423_AT1 and 9550_AT1 and 528_AT2 and 526_AT1) or (51382_AT1 and 9296_AT1 and 534_AT2 and 90423_AT1 and 51606_AT2 and 528_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 534_AT1 and 525_AT1 and 90423_AT1 and 51606_AT2 and 523_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 534_AT2 and 525_AT1 and 90423_AT1 and 51606_AT2 and 528_AT1 and 523_AT1) or (51382_AT1 and 9296_AT1 and 528_AT1 and 525_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 127124_AT2) or (51382_AT1 and 9296_AT1 and 534_AT1 and 529_AT1 and 245973_AT1 and 523_AT1 and 51606_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 528_AT1 and 523_AT1 and 90423_AT1 and 9550_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 127124_AT1 and 245973_AT1 and 90423_AT1 and 51606_AT2 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 528_AT1 and 525_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 9550_AT1) or (51382_AT1 and 9296_AT1 and 529_AT1 and 528_AT1 and 525_AT1 and 523_AT1 and 51606_AT1 and 9550_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 534_AT1 and 529_AT1 and 245973_AT1 and 525_AT1 and 523_AT1) or (51382_AT1 and 9296_AT1 and 245973_AT1 and 525_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 9550_AT1) or (51382_AT1 and 9296_AT1 and 127124_AT1 and 529_AT1 and 245973_AT1 and 525_AT1 and 523_AT1 and 51606_AT1) or (51382_AT1 and 9296_AT1 and 534_AT2 and 525_AT1 and 529_AT1 and 523_AT1 and 51606_AT1 and 528_AT2) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 529_AT1 and 534_AT2 and 523_AT1 and 528_AT2 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 525_AT1 and 90423_AT1 and 127124_AT2 and 523_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 534_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 528_AT2 and 526_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 245973_AT1 and 525_AT1 and 90423_AT1 and 127124_AT2 and 523_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 127124_AT1 and 525_AT1 and 90423_AT1 and 523_AT1 and 528_AT2) or (51382_AT1 and 9296_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 127124_AT2 and 528_AT2 and 526_AT1) or (51382_AT1 and 9296_AT1 and 534_AT1 and 528_AT1 and 525_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 529_AT1 and 245973_AT1 and 525_AT1 and 523_AT1 and 127124_AT2) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 529_AT1 and 525_AT1 and 523_AT1 and 9550_AT1 and 528_AT2) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 529_AT1 and 523_AT1 and 127124_AT2 and 528_AT2 and 526_AT1) or (51382_AT1 and 9296_AT1 and 51606_AT2 and 529_AT1 and 245973_AT1 and 525_AT1 and 523_AT1 and 9550_AT1) or (51382_AT1 and 9296_AT1 and 525_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 127124_AT2 and 528_AT2) or (51382_AT1 and 9296_AT1 and 245973_AT1 and 525_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1 and 127124_AT2) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 127124_AT1 and 529_AT1 and 528_AT1 and 525_AT1 and 523_AT1) or (51382_AT1 and 9296_AT1 and 534_AT2 and 525_AT1 and 529_AT1 and 528_AT1 and 523_AT1 and 51606_AT1) or (51382_AT1 and 51606_AT3 and 9296_AT1 and 534_AT1 and 529_AT1 and 245973_AT1 and 523_AT1 and 526_AT1) or (51382_AT1 and 9296_AT1 and 525_AT1 and 127124_AT2 and 51606_AT2 and 529_AT1 and 528_AT1 and 523_AT1))", "subsystem":"Transport, lysosomal", "notes":{ "original_bigg_ids":[ "ATPasel" ] }, "annotation":{ "bigg.reaction":[ "ATPasel_1" ], "sbo":"SBO:0000185" } }, { "id":"ATPtn", "name":"ATP diffusion in nucleus", "metabolites":{ "atp_c":-1.0, "atp_n":1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Transport, nuclear", "notes":{ "original_bigg_ids":[ "ATPtn" ] }, "annotation":{ "bigg.reaction":[ "ATPtn" ], "biocyc":[ "META:RXN-14913" ], "metanetx.reaction":[ "MNXR96140" ], "sabiork":[ "13978" ], "sbo":"SBO:0000185" } }, { "id":"ATPtx", "name":"ATP transporter, peroxisomal", "metabolites":{ "atp_c":-1.0, "atp_x":1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Transport, 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"name":"Exchange of ArgPheArg", "metabolites":{ "argphearg_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_argphearg[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_argphearg_e" ], "sbo":"SBO:0000627" } }, { "id":"ILEASNHISt", "name":"Transport of IleAsnHis, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "ileasnhis_c":1.0, "ileasnhis_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "ILEASNHISt" ] }, "annotation":{ "bigg.reaction":[ "ILEASNHISt" ], "sbo":"SBO:0000185" } }, { "id":"ILEGLYARGt", "name":"Transport of IleGlyArg, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "ileglyarg_c":1.0, "ileglyarg_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "ILEGLYARGt" ] }, "annotation":{ "bigg.reaction":[ "ILEGLYARGt" ], "sbo":"SBO:0000185" } }, { "id":"ILEPROLYSt", "name":"Transport of IleProLys, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "ileprolys_c":1.0, "ileprolys_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "ILEPROLYSt" ] }, "annotation":{ "bigg.reaction":[ "ILEPROLYSt" ], "sbo":"SBO:0000185" } }, { "id":"ILESERARGt", "name":"Transport of IleSerArg, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "ileserarg_c":1.0, "ileserarg_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "ILESERARGt" ] }, "annotation":{ "bigg.reaction":[ "ILESERARGt" ], "sbo":"SBO:0000185" } }, { "id":"LEUASNASPt", "name":"Transport of LeuAsnAsp, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "leuasnasp_c":1.0, "leuasnasp_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "LEUASNASPt" ] }, "annotation":{ "bigg.reaction":[ "LEUASNASPt" ], "sbo":"SBO:0000185" } }, { "id":"LEUASPLYSt", "name":"Transport of LeuAspLys, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "leuasplys_c":1.0, "leuasplys_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "LEUASPLYSt" ] }, "annotation":{ "bigg.reaction":[ "LEUASPLYSt" ], "sbo":"SBO:0000185" } }, { "id":"LEUPROt", "name":"Transport of LeuPro, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "leupro_c":1.0, "leupro_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "LEUPROt" ] }, "annotation":{ "bigg.reaction":[ "LEUPROt" ], "sbo":"SBO:0000185" } }, { "id":"GLNHISLYSt", "name":"Transport of GlnHisLys, Extracellular", "metabolites":{ "glnhislys_c":1.0, "glnhislys_e":-1.0, "h_c":1.0, "h_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "GLNHISLYSt" ] }, "annotation":{ "bigg.reaction":[ "GLNHISLYSt" ], "sbo":"SBO:0000185" } }, { "id":"EX_argpromet_e", "name":"Exchange of ArgProMet", "metabolites":{ "argpromet_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_argpromet[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_argpromet_e" ], "sbo":"SBO:0000627" } }, { "id":"LEUPROARGt", "name":"Transport of LeuProArg, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "leuproarg_c":1.0, "leuproarg_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "LEUPROARGt" ] }, "annotation":{ "bigg.reaction":[ "LEUPROARGt" ], "sbo":"SBO:0000185" } }, { "id":"LEUTRPt", "name":"Transport of LeuTrp, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "leutrp_c":1.0, "leutrp_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "LEUTRPt" ] }, "annotation":{ "bigg.reaction":[ "LEUTRPt" ], "sbo":"SBO:0000185" } }, { "id":"EX_argprothr_e", "name":"Exchange of ArgProThr", "metabolites":{ "argprothr_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_argprothr[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_argprothr_e" ], "sbo":"SBO:0000627" } }, { "id":"LEUTRPARGt", "name":"Transport of LeuTrpArg, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "leutrparg_c":1.0, "leutrparg_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "LEUTRPARGt" ] }, "annotation":{ "bigg.reaction":[ "LEUTRPARGt" ], "sbo":"SBO:0000185" } }, { "id":"LEUVALt", "name":"Transport of LeuVal, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "leuval_c":1.0, "leuval_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "LEUVALt" ] }, "annotation":{ "bigg.reaction":[ "LEUVALt" ], "sbo":"SBO:0000185" } }, { "id":"EX_argtyrval_e", "name":"Exchange of ArgtyrVal", "metabolites":{ "argtyrval_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_argtyrval[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_argtyrval_e" ], "sbo":"SBO:0000627" } }, { "id":"LYSARGLEUt", "name":"Transport of LysArgLeu, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "lysargleu_c":1.0, "lysargleu_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "LYSARGLEUt" ] }, "annotation":{ "bigg.reaction":[ "LYSARGLEUt" ], "sbo":"SBO:0000185" } }, { "id":"EX_argvalcys_e", "name":"Exchange of ArgValCys", "metabolites":{ "argvalcys_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_argvalcys[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_argvalcys_e" ], "sbo":"SBO:0000627" } }, { "id":"SERTRPHISt", "name":"Transport of SerTrpHis, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "sertrphis_c":1.0, "sertrphis_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "SERTRPHISt" ] }, "annotation":{ "bigg.reaction":[ "SERTRPHISt" ], "sbo":"SBO:0000185" } }, { "id":"LYSGLNPHEt", "name":"Transport of LysGlnPhe, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "lysglnphe_c":1.0, "lysglnphe_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "LYSGLNPHEt" ] }, "annotation":{ "bigg.reaction":[ "LYSGLNPHEt" ], "sbo":"SBO:0000185" } }, { "id":"EX_argvaltrp_e", "name":"Exchange of ArgValTrp", "metabolites":{ "argvaltrp_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_argvaltrp[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_argvaltrp_e" ], "sbo":"SBO:0000627" } }, { "id":"LYSGLUGLUt", "name":"Transport of LysGluGlu, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "lysgluglu_c":1.0, "lysgluglu_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "LYSGLUGLUt" ] }, "annotation":{ "bigg.reaction":[ "LYSGLUGLUt" ], "sbo":"SBO:0000185" } }, { "id":"LYSLYSLYSt", "name":"Transport of LysLysLys, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "lyslyslys_c":1.0, "lyslyslys_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "LYSLYSLYSt" ] }, "annotation":{ "bigg.reaction":[ "LYSLYSLYSt" ], "sbo":"SBO:0000185" } }, { "id":"LYSTYRILEt", "name":"Transport of LystyrIle, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "lystyrile_c":1.0, "lystyrile_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "LYSTYRILEt" ] }, "annotation":{ "bigg.reaction":[ "LYSTYRILEt" ], "sbo":"SBO:0000185" } }, { "id":"THRHISHISt", "name":"Transport of ThrHisHis, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "thrhishis_c":1.0, "thrhishis_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "THRHISHISt" ] }, "annotation":{ "bigg.reaction":[ "THRHISHISt" ], "sbo":"SBO:0000185" } }, { "id":"EX_asnasnarg_e", "name":"Exchange of AsnAsnArg", "metabolites":{ "asnasnarg_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_asnasnarg[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_asnasnarg_e" ], "sbo":"SBO:0000627" } }, { "id":"THRILEARGt", "name":"Transport of ThrIleArg, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "thrilearg_c":1.0, "thrilearg_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "THRILEARGt" ] }, "annotation":{ "bigg.reaction":[ "THRILEARGt" ], "sbo":"SBO:0000185" } }, { "id":"THRPHEARGt", "name":"Transport of ThrPheArg, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "thrphearg_c":1.0, "thrphearg_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "THRPHEARGt" ] }, "annotation":{ "bigg.reaction":[ "THRPHEARGt" ], "sbo":"SBO:0000185" } }, { "id":"LYSVALPHEt", "name":"Transport of LysValPhe, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "lysvalphe_c":1.0, "lysvalphe_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "LYSVALPHEt" ] }, "annotation":{ "bigg.reaction":[ "LYSVALPHEt" ], "sbo":"SBO:0000185" } }, { "id":"METARGLEUt", "name":"Transport of MetArgLeu, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "metargleu_c":1.0, "metargleu_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "METARGLEUt" ] }, "annotation":{ "bigg.reaction":[ "METARGLEUt" ], "sbo":"SBO:0000185" } }, { "id":"METGLNTYRt", "name":"Transport of MetGlntyr, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "metglntyr_c":1.0, "metglntyr_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "METGLNTYRt" ] }, "annotation":{ "bigg.reaction":[ "METGLNTYRt" ], "sbo":"SBO:0000185" } }, { "id":"THRSERARGt", "name":"Transport of ThrSerArg, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "thrserarg_c":1.0, "thrserarg_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "THRSERARGt" ] }, "annotation":{ "bigg.reaction":[ "THRSERARGt" ], "sbo":"SBO:0000185" } }, { "id":"THRTYRMETt", "name":"Transport of ThrtyrMet, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "thrtyrmet_c":1.0, "thrtyrmet_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "THRTYRMETt" ] }, "annotation":{ "bigg.reaction":[ "THRTYRMETt" ], "sbo":"SBO:0000185" } }, { "id":"TRPARGALAt", "name":"Transport of TrpArgAla, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "trpargala_c":1.0, "trpargala_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TRPARGALAt" ] }, "annotation":{ "bigg.reaction":[ "TRPARGALAt" ], "sbo":"SBO:0000185" } }, { "id":"METGLYARGt", "name":"Transport of MetGlyArg, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "metglyarg_c":1.0, "metglyarg_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "METGLYARGt" ] }, "annotation":{ "bigg.reaction":[ "METGLYARGt" ], "sbo":"SBO:0000185" } }, { "id":"TRPASPASPt", "name":"Transport of TrpAspAsp, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "trpaspasp_c":1.0, "trpaspasp_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TRPASPASPt" ] }, "annotation":{ "bigg.reaction":[ "TRPASPASPt" ], "sbo":"SBO:0000185" } }, { "id":"TRPGLNGLNt", "name":"Transport of TrpGlnGln, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "trpglngln_c":1.0, "trpglngln_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TRPGLNGLNt" ] }, "annotation":{ "bigg.reaction":[ "TRPGLNGLNt" ], "sbo":"SBO:0000185" } }, { "id":"TRPGLUGLYt", "name":"Transport of TrpGluGly, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "trpglugly_c":1.0, "trpglugly_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TRPGLUGLYt" ] }, "annotation":{ "bigg.reaction":[ "TRPGLUGLYt" ], "sbo":"SBO:0000185" } }, { "id":"TRPGLULEUt", "name":"Transport of TrpGluLeu, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "trpgluleu_c":1.0, "trpgluleu_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TRPGLULEUt" ] }, "annotation":{ "bigg.reaction":[ "TRPGLULEUt" ], "sbo":"SBO:0000185" } }, { "id":"TRPGLUTYRt", "name":"Transport of TrpGlutyr, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "trpglutyr_c":1.0, "trpglutyr_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TRPGLUTYRt" ] }, "annotation":{ "bigg.reaction":[ "TRPGLUTYRt" ], "sbo":"SBO:0000185" } }, { "id":"METTRPPHEt", "name":"Transport of MetTrpPhe, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "mettrpphe_c":1.0, "mettrpphe_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "METTRPPHEt" ] }, "annotation":{ "bigg.reaction":[ "METTRPPHEt" ], "sbo":"SBO:0000185" } }, { "id":"PHEASNMETt", "name":"Transport of PheAsnMet, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "pheasnmet_c":1.0, "pheasnmet_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PHEASNMETt" ] }, "annotation":{ "bigg.reaction":[ "PHEASNMETt" ], "sbo":"SBO:0000185" } }, { "id":"PHEASPt", "name":"Transport of PheAsp, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "pheasp_c":1.0, "pheasp_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PHEASPt" ] }, "annotation":{ "bigg.reaction":[ "PHEASPt" ], "sbo":"SBO:0000185" } }, { "id":"PHELEUt", "name":"Transport of PheLeu, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "pheleu_c":1.0, "pheleu_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PHELEUt" ] }, "annotation":{ "bigg.reaction":[ "PHELEUt" ], "sbo":"SBO:0000185" } }, { "id":"PHELEUASPt", "name":"Transport of PheLeuAsp, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "pheleuasp_c":1.0, "pheleuasp_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PHELEUASPt" ] }, "annotation":{ "bigg.reaction":[ "PHELEUASPt" ], "sbo":"SBO:0000185" } }, { "id":"PHELEUHISt", "name":"Transport of PheLeuHis, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "pheleuhis_c":1.0, "pheleuhis_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PHELEUHISt" ] }, "annotation":{ "bigg.reaction":[ "PHELEUHISt" ], "sbo":"SBO:0000185" } }, { "id":"TRPGLYPHEt", "name":"Transport of TrpGlyPhe, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "trpglyphe_c":1.0, "trpglyphe_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TRPGLYPHEt" ] }, "annotation":{ "bigg.reaction":[ "TRPGLYPHEt" ], "sbo":"SBO:0000185" } }, { "id":"TRPGLYVALt", "name":"Transport of TrpGlyVal, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "trpglyval_c":1.0, "trpglyval_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TRPGLYVALt" ] }, "annotation":{ "bigg.reaction":[ "TRPGLYVALt" ], "sbo":"SBO:0000185" } }, { "id":"TRPILETRPt", "name":"Transport of TrpIleTrp, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "trpiletrp_c":1.0, "trpiletrp_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TRPILETRPt" ] }, "annotation":{ "bigg.reaction":[ "TRPILETRPt" ], "sbo":"SBO:0000185" } }, { "id":"PHELYSALAt", "name":"Transport of PheLysAla, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "phelysala_c":1.0, "phelysala_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PHELYSALAt" ] }, "annotation":{ "bigg.reaction":[ "PHELYSALAt" ], "sbo":"SBO:0000185" } }, { "id":"PHELYSPROt", "name":"Transport of PheLysPro, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "phelyspro_c":1.0, "phelyspro_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PHELYSPROt" ] }, "annotation":{ "bigg.reaction":[ "PHELYSPROt" ], "sbo":"SBO:0000185" } }, { "id":"EX_asncyscys_e", "name":"Exchange of AsnCysCys", "metabolites":{ "asncyscys_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_asncyscys[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_asncyscys_e" ], "sbo":"SBO:0000627" } }, { "id":"PHEPHEASNt", "name":"Transport of PhePheAsn, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "phepheasn_c":1.0, "phepheasn_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PHEPHEASNt" ] }, "annotation":{ "bigg.reaction":[ "PHEPHEASNt" ], "sbo":"SBO:0000185" } }, { "id":"PHEPHETHRt", "name":"Transport of PhePheThr, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "phephethr_c":1.0, "phephethr_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PHEPHETHRt" ] }, "annotation":{ "bigg.reaction":[ "PHEPHETHRt" ], "sbo":"SBO:0000185" } }, { "id":"TRPLEUVALt", "name":"Transport of TrpLeuVal, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "trpleuval_c":1.0, "trpleuval_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TRPLEUVALt" ] }, "annotation":{ "bigg.reaction":[ "TRPLEUVALt" ], "sbo":"SBO:0000185" } }, { "id":"TRPMETARGt", "name":"Transport of TrpMetArg, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "trpmetarg_c":1.0, "trpmetarg_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TRPMETARGt" ] }, "annotation":{ "bigg.reaction":[ "TRPMETARGt" ], "sbo":"SBO:0000185" } }, { "id":"TRPPHEt", "name":"Transport of TrpPhe, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "trpphe_c":1.0, "trpphe_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TRPPHEt" ] }, "annotation":{ "bigg.reaction":[ "TRPPHEt" ], "sbo":"SBO:0000185" } }, { "id":"TRPPROLEUt", "name":"Transport of TrpProLeu, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "trpproleu_c":1.0, "trpproleu_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TRPPROLEUt" ] }, "annotation":{ "bigg.reaction":[ "TRPPROLEUt" ], "sbo":"SBO:0000185" } }, { "id":"TRPSERTYRt", "name":"Transport of TrpSertyr, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "trpsertyr_c":1.0, "trpsertyr_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TRPSERTYRt" ] }, "annotation":{ "bigg.reaction":[ "TRPSERTYRt" ], "sbo":"SBO:0000185" } }, { "id":"PHETHRLYSt", "name":"Transport of PheThrLys, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "phethrlys_c":1.0, "phethrlys_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PHETHRLYSt" ] }, "annotation":{ "bigg.reaction":[ "PHETHRLYSt" ], "sbo":"SBO:0000185" } }, { "id":"PHETYRGLNt", "name":"Transport of PhetyrGln, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "phetyrgln_c":1.0, "phetyrgln_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PHETYRGLNt" ] }, "annotation":{ "bigg.reaction":[ "PHETYRGLNt" ], "sbo":"SBO:0000185" } }, { "id":"PROARGASPt", "name":"Transport of ProArgAsp, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "proargasp_c":1.0, "proargasp_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PROARGASPt" ] }, "annotation":{ "bigg.reaction":[ "PROARGASPt" ], "sbo":"SBO:0000185" } }, { "id":"PROASNCYSt", "name":"Transport of ProAsnCys, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "proasncys_c":1.0, "proasncys_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PROASNCYSt" ] }, "annotation":{ "bigg.reaction":[ "PROASNCYSt" ], "sbo":"SBO:0000185" } }, { "id":"TRPTHRILEt", "name":"Transport of TrpThrIle, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "trpthrile_c":1.0, "trpthrile_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TRPTHRILEt" ] }, "annotation":{ "bigg.reaction":[ "TRPTHRILEt" ], "sbo":"SBO:0000185" } }, { "id":"TRPTHRTYRt", "name":"Transport of TrpThrtyr, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "trpthrtyr_c":1.0, "trpthrtyr_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TRPTHRTYRt" ] }, "annotation":{ "bigg.reaction":[ "TRPTHRTYRt" ], "sbo":"SBO:0000185" } }, { "id":"TRPTYRGLNt", "name":"Transport of TrptyrGln, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "trptyrgln_c":1.0, "trptyrgln_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TRPTYRGLNt" ] }, "annotation":{ "bigg.reaction":[ "TRPTYRGLNt" ], "sbo":"SBO:0000185" } }, { "id":"PROGLNPROt", "name":"Transport of ProGlnPro, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "proglnpro_c":1.0, "proglnpro_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PROGLNPROt" ] }, "annotation":{ "bigg.reaction":[ "PROGLNPROt" ], "sbo":"SBO:0000185" } }, { "id":"PROHISt", "name":"Transport of ProHis, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "prohis_c":1.0, "prohis_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PROHISt" ] }, "annotation":{ "bigg.reaction":[ "PROHISt" ], "sbo":"SBO:0000185" } }, { "id":"PROHISTYRt", "name":"Transport of ProHistyr, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "prohistyr_c":1.0, "prohistyr_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PROHISTYRt" ] }, "annotation":{ "bigg.reaction":[ "PROHISTYRt" ], "sbo":"SBO:0000185" } }, { "id":"PROLEUARGt", "name":"Transport of ProLeuArg, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "proleuarg_c":1.0, "proleuarg_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PROLEUARGt" ] }, "annotation":{ "bigg.reaction":[ "PROLEUARGt" ], "sbo":"SBO:0000185" } }, { "id":"PROLYSPROt", "name":"Transport of ProLysPro, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "prolyspro_c":1.0, "prolyspro_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PROLYSPROt" ] }, "annotation":{ "bigg.reaction":[ "PROLYSPROt" ], "sbo":"SBO:0000185" } }, { "id":"TRPVALASPt", "name":"Transport of TrpValAsp, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "trpvalasp_c":1.0, "trpvalasp_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TRPVALASPt" ] }, "annotation":{ "bigg.reaction":[ "TRPVALASPt" ], "sbo":"SBO:0000185" } }, { "id":"TYRALAt", "name":"Transport of TyrAla, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "tyrala_c":1.0, "tyrala_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TYRALAt" ] }, "annotation":{ "bigg.reaction":[ "TYRALAt" ], "sbo":"SBO:0000185" } }, { "id":"TYRASPARGt", "name":"Transport of TyrAspArg, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "tyrasparg_c":1.0, "tyrasparg_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TYRASPARGt" ] }, "annotation":{ "bigg.reaction":[ "TYRASPARGt" ], "sbo":"SBO:0000185" } }, { "id":"TYRGLUt", "name":"Transport of TyrGlu, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "tyrglu_c":1.0, "tyrglu_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TYRGLUt" ] }, "annotation":{ "bigg.reaction":[ "TYRGLUt" ], "sbo":"SBO:0000185" } }, { "id":"TYRLEUARGt", "name":"Transport of TyrLeuArg, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "tyrleuarg_c":1.0, "tyrleuarg_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TYRLEUARGt" ] }, "annotation":{ "bigg.reaction":[ "TYRLEUARGt" ], "sbo":"SBO:0000185" } }, { "id":"TYRPHETYRt", "name":"Transport of TyrPhetyr, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "tyrphetyr_c":1.0, "tyrphetyr_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "TYRPHETYRt" ] }, "annotation":{ "bigg.reaction":[ "TYRPHETYRt" ], "sbo":"SBO:0000185" } }, { "id":"PROPROPROt", "name":"Transport of ProProPro, Extracellular", "metabolites":{ "h_c":1.0, "h_e":-1.0, "propropro_c":1.0, "propropro_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6564_AT1 or 6565_AT1", "subsystem":"Transport, extracellular", "notes":{ "original_bigg_ids":[ "PROPROPROt" ] }, "annotation":{ "bigg.reaction":[ "PROPROPROt" ], "sbo":"SBO:0000185" } }, { "id":"PROTRPTHRt", "name":"Transport of ProTrpThr, Extracellular", 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"subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_13dmt[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_13dmt_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_1513tacr_e", "name":"Exchange reaction for 13,15-O-didesmethyl tacrolimus in intestinal lumen", "metabolites":{ "1513tacr_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_1513tacr[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_1513tacr_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_1hibupglu__S_e", "name":"Exchange reaction for 1-hydroxy S-ibuprofen-glucuronide in hepatic vein", "metabolites":{ "1hibupglu__S_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_1hibupglu_S[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_1hibupglu__S_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_2hatvacidgluc_e", "name":"Exchange reaction 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"notes":{ "original_bigg_ids":[ "DM_btn[n]" ] }, "annotation":{ "bigg.reaction":[ "DM_btn_n" ], "sbo":"SBO:0000628" } }, { "id":"DCMPtm", "name":"DCMPtm", "metabolites":{ "dcmp_c":1.0, "dcmp_m":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Transport, mitochondrial", "notes":{ "original_bigg_ids":[ "DCMPtm" ] }, "annotation":{ "bigg.reaction":[ "DCMPtm" ], "sbo":"SBO:0000185" } }, { "id":"DM_protein_c", "name":"DM PROTEIN", "metabolites":{ "protein_c":-1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Intracellular demand", "notes":{ "original_bigg_ids":[ "DM_PROTEIN" ] }, "annotation":{ "bigg.reaction":[ "DM_protein_c" ], "sbo":"SBO:0000628" } }, { "id":"ATPS4mi", "name":"ATP synthase (four protons for one ATP)", "metabolites":{ "adp_m":-1.0, "atp_m":1.0, "h2o_m":1.0, "h_i":-4.0, "h_m":3.0, "pi_m":-1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"((513_AT1 and 498_AT2 and 506_AT1 and 509_AT2 and 514_AT1) or (498_AT2 and 513_AT2 and 514_AT2 and 506_AT1 and 509_AT2) or (513_AT1 and 509_AT1 and 498_AT1 and 514_AT2 and 506_AT1) or (498_AT2 and 513_AT2 and 506_AT1 and 509_AT2 and 514_AT1) or (513_AT2 and 498_AT1 and 514_AT2 and 506_AT1 and 509_AT2) or (513_AT1 and 498_AT1 and 506_AT1 and 509_AT2 and 514_AT1) or (513_AT1 and 498_AT2 and 514_AT2 and 506_AT1 and 509_AT2) or (513_AT1 and 498_AT2 and 509_AT1 and 506_AT1 and 514_AT1) or (498_AT2 and 509_AT1 and 513_AT2 and 506_AT1 and 514_AT1) or (513_AT2 and 498_AT1 and 506_AT1 and 509_AT2 and 514_AT1) or (513_AT2 and 514_AT2 and 506_AT1 and 509_AT2 and 498_AT3) or (513_AT2 and 506_AT1 and 509_AT2 and 498_AT3 and 514_AT1) or (513_AT1 and 509_AT1 and 506_AT1 and 498_AT3 and 514_AT1) or (509_AT1 and 513_AT2 and 514_AT2 and 506_AT1 and 498_AT3) or (513_AT1 and 498_AT2 and 509_AT1 and 514_AT2 and 506_AT1) or (513_AT1 and 498_AT1 and 514_AT2 and 506_AT1 and 509_AT2) or (513_AT1 and 509_AT1 and 498_AT1 and 506_AT1 and 514_AT1) or (513_AT1 and 506_AT1 and 509_AT2 and 498_AT3 and 514_AT1) or (509_AT1 and 513_AT2 and 506_AT1 and 498_AT3 and 514_AT1) or (513_AT1 and 514_AT2 and 506_AT1 and 509_AT2 and 498_AT3) or (509_AT1 and 513_AT2 and 498_AT1 and 506_AT1 and 514_AT1) or (513_AT1 and 509_AT1 and 514_AT2 and 506_AT1 and 498_AT3) or (498_AT2 and 509_AT1 and 513_AT2 and 514_AT2 and 506_AT1) or (509_AT1 and 513_AT2 and 498_AT1 and 514_AT2 and 506_AT1)) and ((10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 522_AT5 and 516_AT2 and 521_AT1 and 515_AT1) or (518_AT3 and 4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT3) or (4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 9551_AT2 and 522_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT5 and 9551_AT2 and 518_AT2 and 521_AT1 and 515_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5) or (518_AT3 and 4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT4) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT2 and 515_AT2 and 518_AT2 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT2 and 522_AT4 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT2 and 9551_AT3 and 518_AT2 and 521_AT1) or (4905_AT1 and 9551_AT1 and 10476_AT2 and 522_AT1 and 516_AT2 and 521_AT1 and 515_AT1 and 10632_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 522_AT1 and 9551_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT5 and 518_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 518_AT2 and 522_AT4 and 521_AT1 and 515_AT1) or (4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5 and 518_AT2) or (4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 522_AT3) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT1 and 522_AT3 and 521_AT1 and 515_AT1) or (4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT5 and 518_AT2 and 9551_AT2) or (4905_AT1 and 9551_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 518_AT2 and 522_AT3) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT4 and 521_AT1) or (4905_AT1 and 10476_AT2 and 522_AT1 and 521_AT1 and 515_AT1 and 10632_AT1 and 518_AT2 and 9551_AT2) or (4905_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 9551_AT2) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT4 and 521_AT1 and 515_AT1) or (518_AT3 and 4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT4) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT1 and 9551_AT2 and 518_AT2 and 521_AT1) or (4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 522_AT5) or (4905_AT1 and 10476_AT2 and 516_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3 and 522_AT3) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT1 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT3 and 10476_AT2 and 522_AT1 and 521_AT1 and 515_AT1) or (4905_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3) or (4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 522_AT4) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT5 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 515_AT3 and 10476_AT2 and 9551_AT2 and 522_AT4 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 517_AT2 and 515_AT2 and 522_AT1 and 9551_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT3 and 522_AT3 and 521_AT1 and 515_AT1) or (4905_AT1 and 10476_AT2 and 521_AT1 and 518_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3 and 522_AT3) or (517_AT1 and 4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT3) or (4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 518_AT2 and 522_AT3) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT2 and 515_AT2 and 521_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 518_AT2 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 515_AT2 and 9551_AT2 and 518_AT2 and 521_AT1) or (4905_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 9551_AT2) or (4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 9551_AT2 and 522_AT3) or (4905_AT1 and 522_AT2 and 10476_AT2 and 516_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT3 and 522_AT5 and 9551_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT2 and 9551_AT3 and 516_AT2 and 521_AT1) or (518_AT3 and 4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT4 and 516_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT1 and 522_AT2 and 515_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 522_AT5 and 521_AT1 and 518_AT1 and 515_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT2 and 9551_AT2 and 521_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 9551_AT3 and 515_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 9551_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT3 and 522_AT1 and 9551_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 517_AT2 and 515_AT2 and 522_AT5 and 521_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT4 and 518_AT2) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 522_AT5 and 9551_AT2 and 521_AT1 and 518_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT2 and 515_AT2 and 516_AT2 and 521_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 517_AT2 and 9551_AT3) or (518_AT3 and 4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT5 and 9551_AT2) or (4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 517_AT2 and 9551_AT2 and 522_AT3) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT5 and 521_AT1) or (517_AT1 and 4905_AT1 and 9551_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT5) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 517_AT2 and 515_AT2 and 522_AT4 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT1 and 516_AT2 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT5 and 521_AT1) or (4905_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 518_AT2) or (518_AT3 and 4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT2 and 522_AT3) or (517_AT1 and 4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT4 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT1 and 516_AT2 and 521_AT1) or (4905_AT1 and 10476_AT2 and 516_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT5 and 9551_AT2) or (518_AT3 and 4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT3) or (517_AT1 and 4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT4) or (4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT4 and 518_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT4 and 521_AT1 and 518_AT1) or (518_AT3 and 4905_AT1 and 522_AT2 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT4 and 516_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 9551_AT3 and 517_AT2 and 515_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT2 and 522_AT4 and 521_AT1 and 515_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 9551_AT3 and 522_AT4) or (4905_AT1 and 9551_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1) or (4905_AT1 and 522_AT2 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3 and 518_AT2) or (518_AT3 and 4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT5) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 9551_AT3 and 521_AT1 and 515_AT1) or (4905_AT1 and 9551_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT5 and 518_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT5 and 518_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT4 and 516_AT2 and 521_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT5 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 9551_AT2 and 521_AT1 and 518_AT1 and 515_AT1) or (517_AT1 and 4905_AT1 and 10476_AT2 and 522_AT1 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT2) or (517_AT1 and 4905_AT1 and 9551_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1) or (518_AT3 and 4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT5 and 9551_AT2) or (4905_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 9551_AT2) or (4905_AT1 and 522_AT2 and 10476_AT2 and 521_AT1 and 518_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 518_AT2 and 522_AT4 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 522_AT2 and 10476_AT2 and 9551_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT2 and 516_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 9551_AT3 and 521_AT1 and 518_AT1 and 515_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT4 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 515_AT3 and 10476_AT2 and 9551_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 516_AT2 and 522_AT3 and 521_AT1) or (4905_AT1 and 9551_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT4 and 518_AT2) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 518_AT2 and 9551_AT2 and 522_AT3) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT5 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT1 and 9551_AT2 and 521_AT1 and 518_AT1) or (518_AT3 and 4905_AT1 and 9551_AT1 and 522_AT2 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1) or (4905_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 518_AT2 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT5 and 518_AT2 and 521_AT1 and 515_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 9551_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT2 and 522_AT1 and 9551_AT2 and 521_AT1 and 515_AT1) or (4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 518_AT2 and 522_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 9551_AT2 and 518_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 522_AT1 and 518_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 522_AT2 and 9551_AT3 and 10476_AT2 and 521_AT1 and 515_AT1) or (517_AT1 and 4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2 and 522_AT3) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT5 and 521_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 9551_AT3 and 522_AT5) or (4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 522_AT5 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 522_AT4 and 516_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 522_AT4 and 521_AT1 and 518_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 517_AT2 and 515_AT2 and 522_AT3 and 521_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 9551_AT2 and 522_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 522_AT1 and 9551_AT2 and 521_AT1 and 518_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT4 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT2 and 521_AT1 and 518_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 517_AT2 and 522_AT1 and 521_AT1) or (4905_AT1 and 10476_AT2 and 516_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3 and 522_AT4) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT2 and 522_AT3 and 521_AT1) or (518_AT3 and 4905_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT2) or (4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 522_AT5) or (4905_AT1 and 10476_AT2 and 516_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT2 and 522_AT3) or (4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 522_AT4) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT3 and 522_AT2 and 9551_AT2 and 521_AT1) or (518_AT3 and 4905_AT1 and 9551_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 522_AT3 and 521_AT1 and 518_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT5 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT2 and 522_AT4 and 516_AT2 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT1 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT1 and 521_AT1 and 518_AT1) or (4905_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 9551_AT3) or (518_AT3 and 4905_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT2) or (517_AT1 and 4905_AT1 and 9551_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 9551_AT2 and 521_AT1 and 515_AT1) or (4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 522_AT4) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT5 and 516_AT2 and 521_AT1) or (517_AT1 and 4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT5 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT1 and 516_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 517_AT2 and 522_AT1 and 521_AT1 and 515_AT1) or (518_AT3 and 4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT4 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 517_AT2 and 522_AT3 and 521_AT1 and 515_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT4) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT3 and 521_AT1 and 518_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 517_AT2 and 515_AT2 and 522_AT3 and 521_AT1) or (4905_AT1 and 10476_AT2 and 522_AT1 and 521_AT1 and 515_AT1 and 10632_AT1 and 517_AT2 and 9551_AT3) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT1 and 9551_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT2 and 9551_AT3 and 521_AT1 and 518_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 518_AT2 and 522_AT3 and 521_AT1 and 515_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 515_AT2 and 9551_AT2 and 521_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT5 and 518_AT2 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 9551_AT3 and 515_AT2 and 521_AT1 and 518_AT1) or (4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 518_AT2 and 9551_AT2 and 522_AT3) or (4905_AT1 and 10476_AT2 and 516_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT4 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT2 and 9551_AT2 and 521_AT1 and 518_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 517_AT2 and 522_AT1 and 9551_AT2 and 521_AT1) or (518_AT3 and 4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5) or (10632_AT1 and 4905_AT1 and 516_AT1 and 515_AT2 and 10476_AT2 and 522_AT5 and 9551_AT2 and 521_AT1) or (517_AT1 and 4905_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 9551_AT3 and 518_AT2 and 521_AT1 and 515_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 522_AT4 and 9551_AT2) or (518_AT3 and 4905_AT1 and 9551_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT5 and 9551_AT2 and 518_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT3 and 522_AT1 and 521_AT1 and 515_AT1) or (4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 522_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 517_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT2 and 516_AT2 and 521_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT2 and 522_AT3 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT1 and 10476_AT2 and 522_AT5 and 521_AT1 and 515_AT1) or (4905_AT1 and 522_AT2 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 517_AT2 and 9551_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 517_AT2 and 515_AT2 and 522_AT1 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 522_AT5 and 9551_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 9551_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 516_AT2 and 522_AT3 and 521_AT1 and 515_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT5 and 521_AT1 and 515_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 9551_AT3 and 522_AT3) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 9551_AT3 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT2 and 518_AT2 and 522_AT3 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 9551_AT2 and 518_AT2 and 522_AT4 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT5 and 9551_AT2 and 521_AT1 and 518_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT5 and 521_AT1 and 518_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5 and 518_AT2) or (4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 517_AT2) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT1 and 522_AT1 and 521_AT1 and 515_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 516_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT3 and 9551_AT2 and 522_AT4 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT2 and 517_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT3 and 9551_AT2 and 522_AT3 and 521_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 521_AT1 and 518_AT1 and 10632_AT1 and 9551_AT2) or (4905_AT1 and 10476_AT2 and 521_AT1 and 518_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3 and 522_AT4) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT1 and 522_AT5 and 521_AT1 and 515_AT1) or (4905_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 518_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 517_AT2 and 515_AT2 and 9551_AT2 and 522_AT3 and 521_AT1) or (4905_AT1 and 10476_AT2 and 521_AT1 and 518_AT1 and 515_AT1 and 10632_AT1 and 522_AT4 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 518_AT2 and 522_AT3 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT1 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 518_AT2 and 522_AT4 and 521_AT1) or (517_AT1 and 4905_AT1 and 9551_AT1 and 10476_AT2 and 522_AT1 and 521_AT1 and 515_AT1 and 10632_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 518_AT2 and 522_AT4 and 521_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT1 and 516_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT5 and 516_AT2 and 521_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 522_AT5 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT1 and 516_AT2 and 521_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 522_AT4 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 518_AT2 and 522_AT3 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 517_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 517_AT2 and 522_AT3 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 522_AT5 and 9551_AT2 and 518_AT2 and 521_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 522_AT1 and 9551_AT2 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT3 and 521_AT1) or (518_AT3 and 4905_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3) or (4905_AT1 and 10476_AT2 and 521_AT1 and 518_AT1 and 515_AT1 and 10632_AT1 and 9551_AT2 and 522_AT3) or (517_AT1 and 4905_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT3 and 10476_AT2 and 522_AT3 and 521_AT1 and 515_AT1) or (518_AT3 and 4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT5) or (4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 522_AT5) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT3 and 515_AT2 and 10476_AT2 and 522_AT5 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT5 and 521_AT1) or (518_AT3 and 4905_AT1 and 9551_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT5) or (517_AT1 and 4905_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3) or (518_AT3 and 4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2 and 522_AT3) or (4905_AT1 and 10476_AT2 and 516_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5) or (10632_AT1 and 4905_AT1 and 516_AT1 and 515_AT2 and 10476_AT2 and 9551_AT2 and 522_AT4 and 521_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 522_AT4 and 9551_AT2) or (4905_AT1 and 10476_AT2 and 521_AT1 and 518_AT1 and 515_AT1 and 10632_AT1 and 522_AT5 and 9551_AT2) or (517_AT1 and 4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT3) or (4905_AT1 and 9551_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2) or (4905_AT1 and 515_AT3 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT3) or (4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5 and 518_AT2) or (4905_AT1 and 522_AT2 and 10476_AT2 and 516_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 522_AT2 and 9551_AT3 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 518_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 522_AT2 and 515_AT2 and 9551_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 517_AT2 and 522_AT5 and 521_AT1) or (517_AT1 and 4905_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT1 and 10476_AT2 and 522_AT4 and 521_AT1 and 515_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT5 and 9551_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 522_AT1 and 9551_AT2 and 516_AT2 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 9551_AT2 and 522_AT4 and 521_AT1) or (517_AT1 and 4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 9551_AT3 and 516_AT2 and 521_AT1 and 515_AT1) or (4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3 and 522_AT4 and 518_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 522_AT1 and 521_AT1 and 518_AT1 and 515_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT3 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 522_AT4 and 521_AT1 and 515_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 516_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT1 and 518_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT3 and 521_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT1 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 517_AT2 and 522_AT4 and 521_AT1) or (4905_AT1 and 9551_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 9551_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 9551_AT2 and 522_AT4 and 521_AT1 and 518_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT1 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 517_AT2 and 522_AT1 and 9551_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 522_AT5 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 522_AT4 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 517_AT2 and 522_AT1 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT1 and 521_AT1 and 518_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 522_AT3 and 521_AT1 and 515_AT1) or (517_AT1 and 4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT5 and 9551_AT2) or (4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 516_AT2 and 521_AT1 and 10632_AT1) or (4905_AT1 and 9551_AT1 and 10476_AT2 and 522_AT1 and 521_AT1 and 515_AT1 and 10632_AT1 and 518_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT4 and 521_AT1 and 518_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 517_AT2 and 522_AT5 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT5 and 516_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 518_AT2 and 522_AT3 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT1 and 9551_AT2 and 521_AT1 and 515_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT4 and 521_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT1 and 521_AT1 and 515_AT1) or (518_AT3 and 4905_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3) or (518_AT3 and 4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT4) or (4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 522_AT4) or (4905_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 521_AT1 and 518_AT1 and 10632_AT1 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT1 and 521_AT1 and 518_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 522_AT5 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT4 and 521_AT1 and 518_AT1) or (4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 516_AT2 and 521_AT1 and 10632_AT1) or (517_AT1 and 4905_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 517_AT2 and 522_AT5 and 9551_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT2 and 9551_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 9551_AT2 and 522_AT4 and 521_AT1) or (4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 522_AT4) or (518_AT3 and 4905_AT1 and 522_AT2 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3) or (10632_AT1 and 4905_AT1 and 516_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 9551_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT1 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 515_AT3 and 9551_AT3 and 10476_AT2 and 522_AT1 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT5 and 9551_AT2 and 516_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT4 and 521_AT1 and 518_AT1) or (517_AT1 and 4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1) or (4905_AT1 and 522_AT2 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 517_AT2 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT3 and 10476_AT2 and 522_AT4 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 517_AT2 and 9551_AT2 and 522_AT3 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT5 and 521_AT1) or (4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3 and 518_AT2 and 522_AT3) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT2 and 522_AT4 and 521_AT1 and 515_AT1) or (517_AT1 and 4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT3) or (4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 518_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 518_AT2 and 522_AT3 and 521_AT1) or (517_AT1 and 4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5) or (4905_AT1 and 522_AT2 and 10476_AT2 and 521_AT1 and 518_AT1 and 515_AT1 and 10632_AT1 and 9551_AT2) or (517_AT1 and 4905_AT1 and 9551_AT1 and 522_AT2 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 522_AT5 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT2 and 522_AT5 and 9551_AT2 and 521_AT1 and 515_AT1) or (517_AT1 and 4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3 and 522_AT4) or (4905_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 518_AT2 and 9551_AT2) or (4905_AT1 and 9551_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2) or (4905_AT1 and 9551_AT1 and 10476_AT2 and 522_AT1 and 521_AT1 and 515_AT1 and 10632_AT1 and 517_AT2) or (4905_AT1 and 10476_AT2 and 522_AT1 and 516_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT2) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 522_AT1 and 9551_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT1 and 10476_AT2 and 522_AT3 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 517_AT2 and 515_AT2 and 9551_AT2 and 521_AT1) or (4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 521_AT1 and 518_AT1 and 10632_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT4 and 521_AT1) or (4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 522_AT3) or (517_AT1 and 4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5) or (518_AT3 and 4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT4) or (4905_AT1 and 10476_AT2 and 522_AT1 and 521_AT1 and 518_AT1 and 515_AT1 and 10632_AT1 and 9551_AT2) or (4905_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 9551_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT4 and 516_AT2 and 521_AT1) or (4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 522_AT3) or (4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT5 and 518_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 517_AT2 and 9551_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT3 and 515_AT2 and 10476_AT2 and 522_AT4 and 521_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 522_AT5 and 9551_AT2 and 521_AT1 and 515_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 517_AT2 and 9551_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT2 and 517_AT2 and 515_AT2 and 521_AT1) or (518_AT3 and 4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3 and 522_AT4) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT2 and 515_AT2 and 521_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 518_AT2 and 522_AT3) or (517_AT1 and 4905_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT1 and 518_AT2 and 521_AT1 and 515_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT4 and 518_AT2 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT3 and 521_AT1 and 518_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT2 and 521_AT1 and 518_AT1) or (518_AT3 and 4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT5 and 9551_AT2) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT5 and 521_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2 and 522_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT2 and 518_AT2 and 522_AT4 and 521_AT1 and 515_AT1) or (4905_AT1 and 10476_AT2 and 522_AT1 and 521_AT1 and 518_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 518_AT2 and 522_AT4 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT1 and 9551_AT2 and 521_AT1 and 518_AT1 and 515_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 9551_AT3 and 522_AT3) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT2 and 9551_AT3 and 521_AT1) or (4905_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2) or (518_AT3 and 4905_AT1 and 10476_AT2 and 522_AT1 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 522_AT1 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT2 and 518_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT1 and 518_AT2 and 521_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 517_AT2 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 517_AT2 and 522_AT4 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT2 and 522_AT3 and 521_AT1 and 515_AT1) or (4905_AT1 and 9551_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 517_AT2 and 522_AT3) or (4905_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 516_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3) or (517_AT1 and 4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT5) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT2 and 9551_AT3 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 9551_AT2 and 516_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 517_AT2 and 515_AT2 and 522_AT5 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT1 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT5 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT5 and 516_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT2 and 522_AT4 and 521_AT1 and 518_AT1 and 515_AT1) or (517_AT1 and 4905_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT2 and 9551_AT2 and 522_AT4 and 521_AT1) or (4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 522_AT3) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 522_AT5 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 516_AT1 and 515_AT3 and 10476_AT2 and 522_AT5 and 9551_AT2 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT1 and 9551_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT2 and 522_AT4 and 516_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 515_AT3 and 9551_AT3 and 10476_AT2 and 522_AT5 and 521_AT1) or (518_AT3 and 4905_AT1 and 9551_AT1 and 10476_AT2 and 522_AT1 and 521_AT1 and 515_AT1 and 10632_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT2 and 9551_AT2 and 518_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 522_AT1 and 516_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 9551_AT2 and 522_AT3 and 521_AT1 and 518_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 517_AT2 and 522_AT5 and 521_AT1 and 515_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 9551_AT3 and 522_AT3) or (4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 518_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 517_AT2 and 522_AT1 and 521_AT1) or (517_AT1 and 4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1) or (4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 522_AT4) or (4905_AT1 and 9551_AT1 and 522_AT2 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 517_AT2) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT2 and 9551_AT2 and 522_AT4 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 522_AT5 and 9551_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT5 and 9551_AT2 and 516_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT2 and 516_AT2 and 522_AT3 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 522_AT2 and 9551_AT2 and 521_AT1 and 515_AT1) or (517_AT1 and 4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT4 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 516_AT2 and 522_AT3 and 521_AT1) or (4905_AT1 and 10476_AT2 and 521_AT1 and 518_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT5 and 518_AT2 and 521_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT1 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT5 and 518_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 9551_AT2 and 518_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT1 and 521_AT1) or (518_AT3 and 4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT5 and 9551_AT2 and 521_AT1 and 518_AT1) or (518_AT3 and 4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT3) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT4 and 521_AT1) or (517_AT1 and 4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3 and 522_AT3) or (4905_AT1 and 515_AT2 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 522_AT5 and 9551_AT2) or (4905_AT1 and 9551_AT1 and 10476_AT2 and 521_AT1 and 518_AT1 and 515_AT1 and 10632_AT1 and 522_AT5) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 517_AT2 and 9551_AT2 and 522_AT3 and 521_AT1 and 515_AT1) or (4905_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 518_AT2 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT2 and 517_AT2 and 9551_AT2 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT4 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT3 and 515_AT2 and 10476_AT2 and 522_AT3 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 522_AT1 and 521_AT1 and 515_AT1) or (518_AT3 and 4905_AT1 and 9551_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT3) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 9551_AT2 and 522_AT3 and 521_AT1) or (4905_AT1 and 9551_AT1 and 10476_AT2 and 521_AT1 and 518_AT1 and 515_AT1 and 10632_AT1 and 522_AT4) or (4905_AT1 and 9551_AT1 and 10476_AT2 and 516_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT5) or (4905_AT1 and 9551_AT1 and 10476_AT2 and 516_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT4) or (4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 518_AT2 and 522_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT2 and 515_AT2 and 521_AT1 and 518_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT3 and 521_AT1 and 518_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT3 and 521_AT1 and 518_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT2 and 522_AT5 and 9551_AT2 and 521_AT1) or (517_AT1 and 4905_AT1 and 9551_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT4) or (4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 9551_AT3 and 522_AT4) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 9551_AT3 and 515_AT2 and 516_AT2 and 521_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 521_AT1 and 518_AT1 and 10632_AT1 and 9551_AT3) or (4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 517_AT2 and 9551_AT3 and 522_AT4) or (4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT4 and 518_AT2) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 9551_AT3 and 517_AT2 and 521_AT1 and 515_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2 and 522_AT3) or (4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 517_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 518_AT2 and 522_AT4 and 521_AT1) or (518_AT3 and 4905_AT1 and 10476_AT2 and 522_AT1 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT2) or (4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 521_AT1 and 518_AT1 and 10632_AT1) or (4905_AT1 and 9551_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 517_AT2 and 522_AT4) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT3 and 10476_AT2 and 522_AT5 and 521_AT1 and 515_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT1 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT2 and 518_AT2 and 522_AT4 and 521_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT5 and 9551_AT2 and 521_AT1) or (518_AT3 and 4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2 and 522_AT3) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT4 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT5 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 515_AT3 and 9551_AT3 and 10476_AT2 and 522_AT4 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 517_AT2 and 522_AT5 and 9551_AT2 and 521_AT1) or (4905_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 9551_AT2) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT1 and 521_AT1 and 515_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT4 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 515_AT2 and 9551_AT2 and 521_AT1 and 518_AT1) or (517_AT1 and 4905_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3) or (4905_AT1 and 9551_AT1 and 10476_AT2 and 516_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT3) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 521_AT1) or (4905_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 9551_AT3) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT1 and 522_AT4 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 515_AT2 and 9551_AT2 and 516_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT4 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT2 and 522_AT4 and 521_AT1 and 515_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT3 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT1 and 9551_AT2 and 518_AT2 and 521_AT1 and 515_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 9551_AT3 and 522_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 517_AT2 and 522_AT4 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT3 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 515_AT2 and 10476_AT2 and 9551_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT2 and 522_AT3 and 521_AT1 and 518_AT1 and 515_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 522_AT5 and 521_AT1 and 515_AT1) or (517_AT1 and 4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT5) or (4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 517_AT2 and 522_AT5 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT2 and 516_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT2 and 9551_AT2 and 522_AT3 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT4 and 521_AT1 and 518_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 517_AT2 and 515_AT2 and 9551_AT2 and 522_AT4 and 521_AT1) or (518_AT3 and 4905_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT2 and 522_AT3 and 521_AT1 and 515_AT1) or (518_AT3 and 4905_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3) or (517_AT1 and 4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT5 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT5 and 521_AT1 and 518_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 517_AT2 and 522_AT5 and 521_AT1 and 515_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 522_AT3 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT4 and 516_AT2 and 521_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3 and 518_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT2 and 522_AT4 and 521_AT1 and 518_AT1) or (517_AT1 and 4905_AT1 and 522_AT2 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 522_AT4 and 9551_AT2) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT4 and 521_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 9551_AT2 and 516_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT3 and 522_AT5 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 522_AT4 and 521_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT4 and 518_AT2 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT1 and 521_AT1) or (4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 517_AT2 and 522_AT4 and 9551_AT2) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 515_AT2 and 9551_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 515_AT3 and 9551_AT3 and 10476_AT2 and 522_AT3 and 521_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 521_AT1 and 518_AT1 and 10632_AT1 and 9551_AT3) or (4905_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT2 and 517_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 9551_AT3 and 515_AT2 and 518_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT2 and 518_AT2 and 521_AT1) or (4905_AT1 and 10476_AT2 and 522_AT1 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3 and 518_AT2) or (4905_AT1 and 9551_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 517_AT2 and 522_AT5) or (4905_AT1 and 9551_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 518_AT2) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 522_AT5 and 9551_AT2) or (517_AT1 and 4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT3) or (518_AT3 and 4905_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2) or (4905_AT1 and 515_AT2 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT1 and 9551_AT2 and 516_AT2 and 521_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 9551_AT3 and 522_AT5) or (4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 522_AT5) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT2 and 518_AT2 and 521_AT1 and 515_AT1) or (4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 517_AT2 and 9551_AT3 and 522_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 522_AT5 and 9551_AT2 and 516_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 522_AT3 and 521_AT1) or (4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT5 and 518_AT2) or (4905_AT1 and 515_AT3 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT4) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT1 and 522_AT2 and 10476_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 517_AT2 and 9551_AT2 and 522_AT4 and 521_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3 and 518_AT2) or (517_AT1 and 4905_AT1 and 522_AT2 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT3 and 515_AT2 and 10476_AT2 and 522_AT1 and 521_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5) or (4905_AT1 and 515_AT3 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 522_AT4 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT1 and 521_AT1 and 518_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 517_AT2 and 9551_AT2 and 522_AT4 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT1 and 522_AT2 and 521_AT1 and 515_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 9551_AT2 and 522_AT3) or (4905_AT1 and 9551_AT1 and 522_AT2 and 10476_AT2 and 521_AT1 and 518_AT1 and 515_AT1 and 10632_AT1) or (518_AT3 and 4905_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT5 and 518_AT2 and 9551_AT2) or (518_AT3 and 4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT4 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT1 and 521_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT2 and 522_AT4 and 521_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT3 and 521_AT1 and 515_AT1) or (517_AT1 and 4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT4 and 9551_AT2) or (4905_AT1 and 9551_AT1 and 522_AT2 and 10476_AT2 and 516_AT2 and 521_AT1 and 515_AT1 and 10632_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 522_AT5 and 518_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 522_AT5 and 9551_AT2 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT2 and 522_AT3 and 521_AT1) or (518_AT3 and 4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT3) or (4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 522_AT4 and 9551_AT2) or (4905_AT1 and 522_AT2 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 518_AT2 and 9551_AT2) or (517_AT1 and 4905_AT1 and 10476_AT2 and 522_AT1 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT1 and 518_AT2 and 521_AT1) or (4905_AT1 and 9551_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 518_AT2) or (4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT4 and 518_AT2 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 516_AT2 and 522_AT3 and 521_AT1) or (517_AT1 and 4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT4) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT2 and 522_AT3 and 521_AT1 and 518_AT1) or (4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 522_AT3) or (4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 518_AT2 and 9551_AT2 and 522_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 517_AT2 and 515_AT2 and 522_AT1 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT1 and 9551_AT2 and 516_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 522_AT2 and 9551_AT3 and 515_AT2 and 521_AT1) or (4905_AT1 and 9551_AT1 and 10476_AT2 and 522_AT1 and 521_AT1 and 518_AT1 and 515_AT1 and 10632_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT4 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT1 and 521_AT1 and 518_AT1) or (4905_AT1 and 10476_AT2 and 522_AT1 and 521_AT1 and 515_AT1 and 10632_AT1 and 517_AT2 and 9551_AT2) or (517_AT1 and 4905_AT1 and 9551_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT3) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 522_AT5 and 521_AT1) or (518_AT3 and 4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT4 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT5 and 521_AT1 and 518_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 516_AT2 and 522_AT3 and 521_AT1 and 515_AT1) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT4 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT3 and 521_AT1 and 518_AT1 and 515_AT1) or (517_AT1 and 4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT4) or (518_AT3 and 4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5) or (518_AT3 and 4905_AT1 and 9551_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 522_AT4) or (10632_AT1 and 4905_AT1 and 516_AT1 and 522_AT2 and 9551_AT3 and 515_AT2 and 10476_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT1 and 10476_AT2 and 522_AT1 and 521_AT1 and 515_AT1) or (4905_AT1 and 9551_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT2 and 522_AT1 and 9551_AT2 and 521_AT1) or (4905_AT1 and 522_AT2 and 515_AT2 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 9551_AT3) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 517_AT2 and 515_AT2 and 522_AT5 and 9551_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT5 and 521_AT1 and 518_AT1) or (518_AT3 and 4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1) or (4905_AT1 and 9551_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT2 and 522_AT1 and 518_AT2 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 9551_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT2 and 9551_AT2 and 516_AT2 and 521_AT1) or (4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT4 and 518_AT2) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT3 and 522_AT2 and 9551_AT3 and 521_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 517_AT2 and 9551_AT2) or (4905_AT1 and 10476_AT2 and 522_AT1 and 516_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3) or (4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 517_AT2 and 9551_AT3 and 522_AT5) or (517_AT1 and 4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2 and 522_AT3) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT3 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 515_AT3 and 522_AT2 and 9551_AT3 and 10476_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT5 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 522_AT1 and 9551_AT2 and 518_AT2 and 521_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 522_AT4 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 517_AT2 and 522_AT4 and 521_AT1 and 515_AT1) or (4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 522_AT5) or (4905_AT1 and 9551_AT1 and 10476_AT2 and 521_AT1 and 518_AT1 and 515_AT1 and 10632_AT1 and 522_AT3) or (4905_AT1 and 9551_AT1 and 522_AT2 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 518_AT2) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT2 and 9551_AT3 and 517_AT2 and 521_AT1) or (518_AT3 and 4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT3 and 522_AT3) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT3 and 515_AT2 and 522_AT3 and 521_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 518_AT1 and 10632_AT1 and 9551_AT3 and 522_AT4) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 517_AT2 and 515_AT2 and 522_AT4 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 522_AT1 and 9551_AT2 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT5 and 9551_AT2 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT2 and 9551_AT2 and 522_AT4 and 516_AT2 and 521_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 522_AT1 and 516_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2) or (517_AT1 and 4905_AT1 and 10476_AT2 and 521_AT1 and 515_AT1 and 10632_AT1 and 9551_AT2 and 522_AT3) or (517_AT1 and 4905_AT1 and 9551_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT4) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 516_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 4905_AT1 and 516_AT1 and 9551_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 521_AT1) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 522_AT2 and 9551_AT3 and 515_AT2 and 521_AT1) or (4905_AT1 and 515_AT2 and 10476_AT2 and 521_AT1 and 10632_AT1 and 517_AT2 and 9551_AT3 and 522_AT4) or (518_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 522_AT2 and 9551_AT2 and 521_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 522_AT5 and 521_AT1 and 518_AT1 and 515_AT1) or (4905_AT1 and 515_AT3 and 522_AT2 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2) or (10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 9551_AT3 and 522_AT4 and 521_AT1 and 515_AT1) or (10632_AT1 and 4905_AT1 and 10476_AT1 and 9551_AT1 and 515_AT3 and 522_AT5 and 516_AT2 and 521_AT1) or (4905_AT1 and 9551_AT1 and 515_AT2 and 10476_AT2 and 516_AT2 and 521_AT1 and 10632_AT1 and 522_AT5) or (10632_AT1 and 517_AT1 and 4905_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT3 and 521_AT1)) and (539_AT1 and 267020_AT1 and 27109_AT1)", "subsystem":"Oxidative phosphorylation", "notes":{ "original_bigg_ids":[ "ATPS4mi" ] }, "annotation":{ "bigg.reaction":[ "ATPS4mi" ], "sbo":"SBO:0000185" } }, { "id":"CYOR_u10mi", "name":"CYOR u10mi", "metabolites":{ "ficytC_m":-2.0, "focytC_m":2.0, "h_i":4.0, "h_m":-2.0, "q10_m":1.0, "q10h2_m":-1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"(7384_AT1 and 7388_AT1 and 4519_AT1 and 29796_AT2 and 10975_AT1 and 7385_AT1 and 7386_AT1 and 1537_AT1 and 27089_AT1 and 7381_AT1) or (7384_AT1 and 7388_AT1 and 4519_AT1 and 29796_AT1 and 10975_AT1 and 7385_AT1 and 1537_AT1 and 7386_AT1 and 27089_AT1 and 7381_AT1)", "subsystem":"Oxidative phosphorylation", "notes":{ "original_bigg_ids":[ "CYOR_u10mi" ] }, "annotation":{ "bigg.reaction":[ "CYOR_u10mi" ], "sbo":"SBO:0000185" } }, { "id":"Htmi", "name":"Htmi", "metabolites":{ "h_i":-1.0, "h_m":1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"9016_AT1 or 7352_AT2 or 7352_AT1 or 7351_AT1 or 9016_AT2 or 7350_AT1 or 9481_AT1", "subsystem":"Transport, mitochondrial", "notes":{ "original_bigg_ids":[ "Htmi" ] }, "annotation":{ "bigg.reaction":[ "Htmi" ], "sbo":"SBO:0000185" } }, { "id":"NADH2_u10mi", "name":"NADH2 u10mi", "metabolites":{ "h_i":4.0, "h_m":-5.0, "nad_m":1.0, "nadh_m":-1.0, "q10_m":-1.0, "q10h2_m":1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"(4715_AT1 and 4720_AT1 and 4719_AT1 and 4700_AT1 and 55967_AT1 and 4709_AT1 and 4710_AT1 and 4726_AT1 and 4718_AT1 and 4696_AT1 and 4694_AT1 and 374291_AT1 and 4728_AT1 and 4712_AT2 and 4717_AT1 and 4705_AT1 and 4725_AT1 and 4716_AT1 and 4537_AT1 and 7991_AT1 and 4722_AT1 and 4541_AT1 and 4539_AT1 and 4707_AT1 and 4701_AT1 and 4723_AT1 and 4698_AT1 and 4538_AT1 and 4697_AT1 and 51079_AT1 and 4714_AT1 and 4704_AT1 and 126328_AT1 and 4711_AT1 and 4724_AT1 and 4713_AT1 and 4536_AT1 and 4695_AT1 and 4702_AT1 and 4708_AT1 and 4535_AT1 and 4731_AT2 and 4706_AT1 and 4729_AT1 and 4540_AT1) or (4715_AT1 and 4720_AT1 and 4719_AT1 and 55967_AT1 and 4700_AT1 and 4709_AT1 and 4710_AT1 and 4726_AT1 and 4696_AT1 and 4718_AT1 and 4694_AT1 and 374291_AT1 and 4728_AT1 and 7991_AT2 and 4717_AT1 and 4731_AT1 and 4705_AT1 and 4725_AT1 and 4716_AT1 and 4537_AT1 and 4722_AT1 and 4541_AT1 and 4712_AT1 and 4539_AT1 and 4707_AT1 and 4701_AT1 and 4698_AT1 and 4723_AT1 and 4538_AT1 and 4697_AT1 and 51079_AT1 and 4714_AT1 and 4704_AT1 and 126328_AT1 and 4711_AT1 and 4724_AT1 and 4536_AT1 and 4713_AT1 and 4695_AT1 and 4702_AT1 and 4708_AT1 and 4706_AT1 and 4535_AT1 and 4540_AT1 and 4729_AT1) or (4715_AT1 and 4720_AT1 and 4719_AT1 and 55967_AT1 and 4700_AT1 and 4709_AT1 and 4710_AT1 and 4726_AT1 and 4718_AT1 and 4696_AT1 and 374291_AT1 and 4694_AT1 and 4728_AT1 and 7991_AT2 and 4712_AT2 and 4717_AT1 and 4705_AT1 and 4725_AT1 and 4716_AT1 and 4537_AT1 and 4722_AT1 and 4541_AT1 and 4539_AT1 and 4707_AT1 and 4701_AT1 and 4698_AT1 and 4723_AT1 and 4538_AT1 and 4697_AT1 and 51079_AT1 and 4714_AT1 and 4704_AT1 and 4711_AT1 and 126328_AT1 and 4724_AT1 and 4536_AT1 and 4713_AT1 and 4695_AT1 and 4702_AT1 and 4708_AT1 and 4731_AT2 and 4706_AT1 and 4535_AT1 and 4540_AT1 and 4729_AT1) or (4715_AT1 and 4720_AT1 and 4719_AT1 and 4700_AT1 and 55967_AT1 and 4709_AT1 and 4710_AT1 and 4726_AT1 and 4718_AT1 and 4696_AT1 and 374291_AT1 and 4694_AT1 and 4728_AT1 and 4717_AT1 and 4705_AT1 and 4725_AT1 and 4537_AT1 and 4716_AT1 and 4722_AT1 and 7991_AT1 and 4541_AT1 and 4712_AT1 and 4539_AT1 and 4707_AT1 and 4701_AT1 and 4723_AT1 and 4698_AT1 and 4538_AT1 and 4697_AT1 and 51079_AT1 and 4714_AT1 and 4704_AT1 and 4711_AT1 and 126328_AT1 and 4724_AT1 and 4713_AT1 and 4536_AT1 and 4695_AT1 and 4702_AT1 and 4708_AT1 and 4706_AT1 and 4535_AT1 and 4731_AT2 and 4729_AT1 and 4540_AT1) or (4715_AT1 and 4720_AT1 and 4719_AT1 and 55967_AT1 and 4700_AT1 and 4709_AT1 and 4710_AT1 and 4726_AT1 and 4696_AT1 and 4718_AT1 and 4694_AT1 and 374291_AT1 and 4728_AT1 and 4717_AT1 and 4731_AT1 and 4705_AT1 and 4725_AT1 and 4716_AT1 and 4537_AT1 and 4722_AT1 and 7991_AT1 and 4541_AT1 and 4539_AT1 and 4712_AT1 and 4707_AT1 and 4701_AT1 and 4723_AT1 and 4698_AT1 and 4538_AT1 and 4697_AT1 and 51079_AT1 and 4714_AT1 and 4704_AT1 and 126328_AT1 and 4711_AT1 and 4724_AT1 and 4713_AT1 and 4536_AT1 and 4695_AT1 and 4702_AT1 and 4708_AT1 and 4706_AT1 and 4535_AT1 and 4540_AT1 and 4729_AT1) or (4715_AT1 and 4720_AT1 and 4719_AT1 and 55967_AT1 and 4700_AT1 and 4709_AT1 and 4710_AT1 and 4726_AT1 and 4696_AT1 and 4718_AT1 and 374291_AT1 and 4694_AT1 and 4728_AT1 and 4712_AT2 and 4717_AT1 and 4731_AT1 and 4705_AT1 and 4725_AT1 and 4537_AT1 and 4716_AT1 and 4722_AT1 and 7991_AT1 and 4541_AT1 and 4539_AT1 and 4707_AT1 and 4701_AT1 and 4723_AT1 and 4698_AT1 and 4538_AT1 and 4697_AT1 and 51079_AT1 and 4714_AT1 and 4704_AT1 and 126328_AT1 and 4711_AT1 and 4724_AT1 and 4713_AT1 and 4536_AT1 and 4695_AT1 and 4702_AT1 and 4708_AT1 and 4535_AT1 and 4706_AT1 and 4729_AT1 and 4540_AT1) or (4715_AT1 and 4720_AT1 and 4719_AT1 and 4700_AT1 and 55967_AT1 and 4709_AT1 and 4710_AT1 and 4726_AT1 and 4718_AT1 and 4696_AT1 and 4694_AT1 and 374291_AT1 and 4728_AT1 and 7991_AT2 and 4717_AT1 and 4705_AT1 and 4725_AT1 and 4537_AT1 and 4716_AT1 and 4722_AT1 and 4541_AT1 and 4712_AT1 and 4539_AT1 and 4707_AT1 and 4701_AT1 and 4723_AT1 and 4698_AT1 and 4538_AT1 and 4697_AT1 and 51079_AT1 and 4714_AT1 and 4704_AT1 and 4711_AT1 and 126328_AT1 and 4724_AT1 and 4713_AT1 and 4536_AT1 and 4695_AT1 and 4702_AT1 and 4708_AT1 and 4535_AT1 and 4731_AT2 and 4706_AT1 and 4540_AT1 and 4729_AT1) or (4715_AT1 and 4720_AT1 and 4719_AT1 and 4700_AT1 and 55967_AT1 and 4709_AT1 and 4710_AT1 and 4726_AT1 and 4718_AT1 and 4696_AT1 and 374291_AT1 and 4694_AT1 and 4728_AT1 and 7991_AT2 and 4712_AT2 and 4717_AT1 and 4731_AT1 and 4705_AT1 and 4725_AT1 and 4537_AT1 and 4716_AT1 and 4722_AT1 and 4541_AT1 and 4539_AT1 and 4707_AT1 and 4701_AT1 and 4698_AT1 and 4723_AT1 and 4538_AT1 and 4697_AT1 and 51079_AT1 and 4714_AT1 and 4704_AT1 and 4711_AT1 and 126328_AT1 and 4724_AT1 and 4713_AT1 and 4536_AT1 and 4695_AT1 and 4702_AT1 and 4708_AT1 and 4706_AT1 and 4535_AT1 and 4540_AT1 and 4729_AT1 and 54539_AT1)", "subsystem":"Oxidative phosphorylation", "notes":{ "original_bigg_ids":[ "NADH2_u10mi" ] }, "annotation":{ "bigg.reaction":[ "NADH2_u10mi" ], "sbo":"SBO:0000185" } }, { "id":"CYOOm3i", "name":"CYOOm3i", "metabolites":{ "ficytC_m":4.0, "focytC_m":-4.0, "h2o_m":1.96, "h_i":4.0, "h_m":-7.92, "o2_m":-1.0, "o2s_m":0.02 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"1351_AT1 and 1347_AT1 and 1329_AT1 and 1327_AT1 and 341947_AT1 and 9167_AT1 and 1350_AT1 and 4512_AT1 and 1349_AT1 and 1339_AT1 and 1345_AT1 and 4513_AT1 and 9377_AT1 and 125965_AT1 and 4514_AT1 and 170712_AT1 and 1346_AT1 and 1340_AT1 and 84701_AT1 and 1337_AT1", "subsystem":"Oxidative phosphorylation", "notes":{ "original_bigg_ids":[ "CYOOm3i" ] }, "annotation":{ "bigg.reaction":[ "CYOOm3i" ], "sbo":"SBO:0000185" } }, { "id":"ALLOP1tu", "name":"Uptake of allopurinol by the enterocytes", "metabolites":{ "allop_c":1.0, "allop_e":-1.0, "na1_c":1.0, "na1_e":-1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"9154_AT1 or 9153_AT1 or 64078_AT1", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "ALLOP1tu" ] }, "annotation":{ "bigg.reaction":[ "ALLOP1tu" ], "sbo":"SBO:0000185" } }, { "id":"ALLOPOXDhep", "name":"Oxidation of allopurinol to oxypurinol in hepatocytes", "metabolites":{ "allop_c":-1.0, "h2o2_c":1.0, "h2o_c":-1.0, "o2_c":-1.0, "oxyp_c":1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"7498_AT1 or 316_AT1", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "ALLOPOXDhep" ] }, "annotation":{ "bigg.reaction":[ "ALLOPOXDhep" ], "sbo":"SBO:0000176" } }, { "id":"ALLOPtepvb", "name":"Uptake of allopurinol by the hepatocytes", "metabolites":{ "allop_c":1.0, "allop_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"10864_AT1", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "ALLOPtepvb" ] }, "annotation":{ "bigg.reaction":[ "ALLOPtepvb" ], "sbo":"SBO:0000185" } }, { "id":"AM19CSALThr", "name":"Alternative pathway for formation of AM19 from AM1 in hepatocytes", "metabolites":{ "am19cs_r":1.0, "am1csa_r":-1.0, "h2o_r":1.0, "h_r":-1.0, "nadp_r":1.0, "nadph_r":-1.0, "o2_r":-1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"1576_AT1 or 1577_AT1", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "AM19CSALThr" ] }, "annotation":{ "bigg.reaction":[ "AM19CSALThr" ], "sbo":"SBO:0000176" } }, { "id":"AM1A4NCShc", "name":"Demethylation of AM1A to AM1A4N in hepatocytes", "metabolites":{ "ahcys_c":-1.0, "am1a4ncs_c":1.0, "am1acs_c":-1.0, "amet_c":1.0, "h_c":-1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "AM1A4NCShc" ] }, "annotation":{ "bigg.reaction":[ "AM1A4NCShc" ], "sbo":"SBO:0000176" } }, { "id":"AM1ACCShr", "name":"Oxidation of AM1c to AM1Ac in hepatocytes (alternative mechanism)", "metabolites":{ "am1accs_r":1.0, "am1ccs_r":-1.0, "h2o_r":1.0, "h_r":1.0, "o2_r":-1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "AM1ACCShr" ] }, "annotation":{ "bigg.reaction":[ "AM1ACCShr" ], "sbo":"SBO:0000176" } }, { "id":"AM1ACStep", "name":"Efflux of AM1A (cyclosporine) into portal blood", "metabolites":{ "am1acs_c":-1.0, "am1acs_e":1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "AM1ACStep" ] }, "annotation":{ "bigg.reaction":[ "AM1ACStep" ], "sbo":"SBO:0000185" } }, { "id":"AM1CCStev", "name":"Efflux of AM1c-cyclosporine into hepatic vein", "metabolites":{ "am1ccs_c":-1.0, "am1ccs_e":1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "AM1CCStev" ] }, "annotation":{ "bigg.reaction":[ "AM1CCStev" ], "sbo":"SBO:0000185" } }, { "id":"AM1CGLCteb", "name":"Efflux of AM1c-glucuronide into bile", "metabolites":{ "adp_c":1.0, "am1cglc_c":-1.0, "am1cglc_e":1.0, "atp_c":-1.0, "h2o_c":-1.0, "h_c":1.0, "pi_c":1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "AM1CGLCteb" ] }, "annotation":{ "bigg.reaction":[ "AM1CGLCteb" ], "sbo":"SBO:0000185" } }, { "id":"AM1CSAhr", "name":"Oxidation of cyclosporine to AM1 in hepatocytes", "metabolites":{ "am1csa_r":1.0, "csa_r":-1.0, "h2o_r":1.0, "h_r":-1.0, "nadp_r":1.0, "nadph_r":-1.0, "o2_r":-1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"1576_AT1 or 1577_AT1", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "AM1CSAhr" ] }, "annotation":{ "bigg.reaction":[ "AM1CSAhr" ], "sbo":"SBO:0000176" } }, { "id":"AM4N9CShr", "name":"Oxidation of AM4N to AM4N9 in hepatocytes", "metabolites":{ "am4n9cs_r":1.0, "am4ncs_r":-1.0, "h2o_r":1.0, "h_r":-1.0, "nadp_r":1.0, "nadph_r":-1.0, "o2_r":-1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "AM4N9CShr" ] }, "annotation":{ "bigg.reaction":[ "AM4N9CShr" ], "sbo":"SBO:0000176" } }, { "id":"AM9CSAhr", "name":"Oxidation of cyclosporine to AM9 in hepatocytes", "metabolites":{ "am9csa_r":1.0, "csa_r":-1.0, "h2o_r":1.0, "h_r":-1.0, "nadp_r":1.0, "nadph_r":-1.0, "o2_r":-1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"1576_AT1 or 1577_AT1", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "AM9CSAhr" ] }, "annotation":{ "bigg.reaction":[ "AM9CSAhr" ], "sbo":"SBO:0000176" } }, { "id":"AM9CSAteb", "name":"Efflux of AM9-cyclosporine into bile", "metabolites":{ "adp_c":1.0, "am9csa_c":-1.0, "am9csa_e":1.0, "atp_c":-1.0, "h2o_c":-1.0, "h_c":1.0, "pi_c":1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "AM9CSAteb" ] }, "annotation":{ "bigg.reaction":[ "AM9CSAteb" ], "sbo":"SBO:0000185" } }, { "id":"AM9CSAtep", "name":"Efflux of AM9 (cyclosporine) into portal blood", "metabolites":{ "am9csa_c":-1.0, "am9csa_e":1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "AM9CSAtep" ] }, "annotation":{ "bigg.reaction":[ "AM9CSAtep" ], "sbo":"SBO:0000185" } }, { "id":"ATVACIDMCTtu", "name":"Uptake of atorvastatin by enterocytes by MCT1", "metabolites":{ "atvacid_c":1.0, "atvacid_e":-1.0, "h_c":1.0, "h_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"6566_AT1", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "ATVACIDMCTtu" ] }, "annotation":{ "bigg.reaction":[ "ATVACIDMCTtu" ], "sbo":"SBO:0000185" } }, { "id":"ATVACIDhc", "name":"Conversion of lactone to acid form of atorvastatin in hepatocytes", "metabolites":{ "atvacid_c":1.0, "atvlac_c":-1.0, "h2o_c":-1.0, "h_c":1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"5446_AT1", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "ATVACIDhc" ] }, "annotation":{ "bigg.reaction":[ "ATVACIDhc" ], "sbo":"SBO:0000176" } }, { "id":"ATVACIDhr", "name":"Spontaneous conversion of atorvastatin ether glucuronide (G1) to atorvastatin-acid", "metabolites":{ "atvacid_r":1.0, "atvethgluc_r":-1.0, "glcur_r":2.0, "h2o_r":-2.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "ATVACIDhr" ] }, "annotation":{ "bigg.reaction":[ "ATVACIDhr" ], "sbo":"SBO:0000176" } }, { "id":"ATVACYLGLUChc", "name":"Glucuronidation of atorvastatin to atorvastatin acyl glucuronide (G2) in hepatocytes", "metabolites":{ "atvacid_r":-1.0, "atvacylgluc_r":1.0, "udp_r":1.0, "udpglcur_r":-1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"54659_AT1 or 54657_AT1 or 54658_AT1 or 54576_AT1 or 7364_AT1", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "ATVACYLGLUChc" ] }, "annotation":{ "bigg.reaction":[ "ATVACYLGLUChc" ], "sbo":"SBO:0000176" } }, { "id":"ATVETHGLUChc", "name":"Glucuronidation of atorvastatin to atorvastatin ether glucuronide (G1) in hepatocytes", "metabolites":{ "atvacid_r":-1.0, "atvethgluc_r":1.0, "h_r":2.0, "udp_r":2.0, "udpglcur_r":-2.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"54659_AT1 or 54657_AT1 or 54600_AT1", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "ATVETHGLUChc" ] }, "annotation":{ "bigg.reaction":[ "ATVETHGLUChc" ], "sbo":"SBO:0000176" } }, { "id":"ATVLACThc", "name":"Uptake of atorvastatin-lactone into hepatocytes", "metabolites":{ "atvlac_c":1.0, "atvlac_e":-1.0, "hco3_c":-1.0, "hco3_e":1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"10599_AT1 or 11309_AT1", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "ATVLACThc" ] }, "annotation":{ "bigg.reaction":[ "ATVLACThc" ], "sbo":"SBO:0000185" } }, { "id":"ATVLACh2r", "name":"Spontaneous conversion of glucuronide (G2) to lactone form of atorvastatin", "metabolites":{ "atvacylgluc_r":-1.0, "atvlac_r":1.0, "glcur_r":1.0 }, "lower_bound":0.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Drug metabolism", "notes":{ "original_bigg_ids":[ "ATVLACh2r" ] }, "annotation":{ "bigg.reaction":[ "ATVLACh2r" ], "sbo":"SBO:0000176" } }, { "id":"EX_3hpvstet_e", "name":"Exchange reaction of 3-S-hydroxy-pravastatin-tetranor in hepatic vein", "metabolites":{ "3hpvstet_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_3hpvstet[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_3hpvstet_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_3hsmvacid_e", "name":"Exchange reaction for 3-hydroxy-simvastatin-acid form form in bile", "metabolites":{ "3hsmvacid_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_3hsmvacid[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_3hsmvacid_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_3ispvs_e", "name":"Exchange reaction for 3-alpha-iso-pravastatin in portal blood", "metabolites":{ "3ispvs_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_3ispvs[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_3ispvs_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_4bhglz_e", "name":"Exchange reaction for 4-beta-OH-gliclazide in hepatic vein", "metabolites":{ "4bhglz_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_4bhglz[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_4bhglz_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_4hatvlac_e", "name":"Exchange reaction for 4-hydroxy-atorvastatin-lactone in portal blood", "metabolites":{ "4hatvlac_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_4hatvlac[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_4hatvlac_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_4ohmdz_e", "name":"Exchange reaction for 4-OH-midazolam in hepatic vein", "metabolites":{ "4ohmdz_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_4ohmdz[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_4ohmdz_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_56eppvs_e", "name":"Exchange reaction of 5,6-epoxy-3-alpha-iso-pravastatin in hepatic vein", "metabolites":{ "56eppvs_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_56eppvs[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_56eppvs_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_5ohfvsglu_e", "name":"Exchnage reaction for 5-hydroxy-fluvastatin-glucuronide in hepatic vein", "metabolites":{ "5ohfvsglu_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_5ohfvsglu[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_5ohfvsglu_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_6ahglz_e", "name":"Exchange reaction for 6-alpha-OH-gliclazide in hepatic vein", "metabolites":{ "6ahglz_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_6ahglz[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_6ahglz_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_6bhglz_e", "name":"Exchange reaction for 6-beta-OH-gliclazide in hepatic vein", "metabolites":{ "6bhglz_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_6bhglz[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_6bhglz_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_6bhglzglc_e", "name":"Exchange reaction for 6-beta-OH-gliclazide-glucuronide in hepatic vein", "metabolites":{ "6bhglzglc_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_6bhglzglc[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_6bhglzglc_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_6csmvacid_e", "name":"Exchange reaction for 6-beta-carboxy-simvastatin-acid form in bile", "metabolites":{ "6csmvacid_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_6csmvacid[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_6csmvacid_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_6hlvst_e", "name":"Exchange reaction for 6-beta-hydroxy-lovastatin in portal blood", "metabolites":{ "6hlvst_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_6hlvst[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_6hlvst_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_6hsmvacid_e", "name":"Exchange reaction for 6-beta-hydroxy simvastatin acid in bile", "metabolites":{ "6hsmvacid_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_6hsmvacid[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_6hsmvacid_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_6melvacid_e", "name":"Exchange reaction for 6-exomethylene-lovastatin-acid form in bile", "metabolites":{ "6melvacid_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_6melvacid[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_6melvacid_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_6melvst_e", "name":"Exchange reaction for 6-exomethylene-lovastatin in portal blood", "metabolites":{ "6melvst_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_6melvst[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_6melvst_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_6ohfvsglu_e", "name":"Exchange reaction for 6-hydroxy-fluvastatin-glucuronide in hepatic vein", "metabolites":{ "6ohfvsglu_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_6ohfvsglu[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_6ohfvsglu_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_7bhglzglc_e", "name":"Exchange reaction for 7-beta-OH-gliclazide-glucuronide in hepatic vein", "metabolites":{ "7bhglzglc_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, "gene_reaction_rule":"", "subsystem":"Extracellular exchange", "notes":{ "original_bigg_ids":[ "EX_7bhglzglc[e]" ] }, "annotation":{ "bigg.reaction":[ "EX_7bhglzglc_e" ], "sbo":"SBO:0000627" } }, { "id":"EX_acmp_e", "name":"Exchange reaction for acetaminophen in small intestinal lumen", "metabolites":{ "acmp_e":-1.0 }, "lower_bound":-1000.0, "upper_bound":1000.0, 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