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},
{
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{
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"CHEBI:58418",
"CHEBI:12808",
"CHEBI:53043",
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"CHEBI:81671"
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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"CHEBI:23969",
"CHEBI:42467",
"CHEBI:27974"
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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},
{
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},
{
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{
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{
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},
{
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{
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{
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{
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{
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},
{
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{
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}
},
{
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},
{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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},
{
"id":"lpchol_hs_c",
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},
{
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{
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{
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{
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},
{
"id":"ksi_pre2_g",
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},
{
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},
{
"id":"ksi_pre30_g",
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},
{
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},
{
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},
{
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},
{
"id":"ksi_pre32_g",
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},
{
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{
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{
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{
"id":"ACGALFUCGALACGALFUCGALACGLCGAL14ACGLCGALGLUSIDEtg",
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{
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"R-GGA-74213",
"R-CFA-74213",
"R-OSA-74213",
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"R-SSC-74213",
"R-SPO-74213",
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"R-DRE-74213",
"R-DDI-74213",
"R-MMU-74213",
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"16612",
"16611",
"16609"
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{
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},
{
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{
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"pi_c":1.0
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{
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{
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},
{
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"gene_reaction_rule":"",
"subsystem":"Biotin Metabolism",
"notes":{
"original_bigg_ids":[
"APOC_LYS_BTNPm"
]
},
"annotation":{
"bigg.reaction":[
"APOC_LYS_BTNPm"
],
"metanetx.reaction":[
"MNXR95888"
],
"sbo":"SBO:0000176"
}
},
{
"id":"APPNNte",
"name":"Xenobiotic transport",
"metabolites":{
"appnn_c":1.0,
"appnn_e":-1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Extracellular",
"notes":{
"original_bigg_ids":[
"APPNNte"
]
},
"annotation":{
"bigg.reaction":[
"APPNNte"
],
"metanetx.reaction":[
"MNXR95896"
],
"sbo":"SBO:0000185"
}
},
{
"id":"ALDD21",
"name":"Aldehyde dehydrogenase (pristanal, NAD)",
"metabolites":{
"h2o_c":-1.0,
"h_c":2.0,
"nad_c":-1.0,
"nadh_c":1.0,
"prist_c":1.0,
"pristanal_c":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"224_AT1",
"subsystem":"Fatty Acid Metabolism",
"notes":{
"original_bigg_ids":[
"ALDD21"
]
},
"annotation":{
"bigg.reaction":[
"ALDD21"
],
"metanetx.reaction":[
"MNXR95747"
],
"sbo":"SBO:0000176"
}
},
{
"id":"APRGSTRNte",
"name":"Hydroxyprogesterone transport",
"metabolites":{
"aprgstrn_c":1.0,
"aprgstrn_e":-1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Extracellular",
"notes":{
"original_bigg_ids":[
"APRGSTRNte"
]
},
"annotation":{
"bigg.reaction":[
"APRGSTRNte"
],
"metanetx.reaction":[
"MNXR95899"
],
"sbo":"SBO:0000185"
}
},
{
"id":"ARGSS",
"name":"Argininosuccinate synthase",
"metabolites":{
"amp_c":1.0,
"argsuc_c":1.0,
"asp__L_c":-1.0,
"atp_c":-1.0,
"citr__L_c":-1.0,
"h_c":1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"445_AT2 or 445_AT1",
"subsystem":"Alanine and Aspartate Metabolism",
"notes":{
"original_bigg_ids":[
"ARGSS"
]
},
"annotation":{
"bigg.reaction":[
"ARGSS"
],
"biocyc":[
"META:ARGSUCCINSYN-RXN"
],
"ec-code":[
"6.3.4.5"
],
"kegg.reaction":[
"R01954"
],
"metanetx.reaction":[
"MNXR138060"
],
"reactome.reaction":[
"R-MMU-70577",
"R-RNO-70577",
"R-GGA-70577",
"R-BTA-70577",
"R-SSC-70577",
"R-CFA-70577",
"R-XTR-70577",
"R-TGU-70577",
"R-HSA-70577"
],
"rhea":[
"10933",
"10935",
"10934",
"10932"
],
"sabiork":[
"572"
],
"sbo":"SBO:0000176",
"seed.reaction":[
"rxn01434"
]
}
},
{
"id":"APRTO2",
"name":"N acetylputrescine oxygen oxireductase  deaminating ",
"metabolites":{
"aprut_c":-1.0,
"h2o2_c":1.0,
"h2o_c":-1.0,
"n4abutn_c":1.0,
"nh4_c":1.0,
"o2_c":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"4129_AT1 or 4128_AT1",
"subsystem":"Arginine and Proline Metabolism",
"notes":{
"original_bigg_ids":[
"APRTO2"
]
},
"annotation":{
"bigg.reaction":[
"APRTO2"
],
"biocyc":[
"META:RXN-1"
],
"ec-code":[
"1.4.3.4"
],
"kegg.reaction":[
"R04025"
],
"metanetx.reaction":[
"MNXR95900"
],
"sbo":"SBO:0000176",
"seed.reaction":[
"rxn02826"
]
}
},
{
"id":"AQCOBALt",
"name":"Aquacob(III)alamin uptake",
"metabolites":{
"aqcobal_c":1.0,
"aqcobal_e":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Extracellular",
"notes":{
"original_bigg_ids":[
"AQCOBALt"
]
},
"annotation":{
"bigg.reaction":[
"AQCOBALt"
],
"metanetx.reaction":[
"MNXR95905"
],
"sbo":"SBO:0000185"
}
},
{
"id":"ARABR",
"name":"Arabinose reductase",
"metabolites":{
"abt_c":1.0,
"arab__L_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"8574_AT1 or 231_AT1 or 10327_AT1 or 10327_AT2",
"subsystem":"Pentose and Glucuronate Interconversions",
"notes":{
"original_bigg_ids":[
"ARABR"
]
},
"annotation":{
"bigg.reaction":[
"ARABR"
],
"ec-code":[
"1.1.1.21",
"1.1.1.2"
],
"metanetx.reaction":[
"MNXR95911"
],
"sabiork":[
"1858"
],
"sbo":"SBO:0000176"
}
},
{
"id":"ARAB_Lt",
"name":"L arabinoase extracellular transport",
"metabolites":{
"arab__L_c":1.0,
"arab__L_e":-1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Extracellular",
"notes":{
"original_bigg_ids":[
"ARAB_Lt"
]
},
"annotation":{
"bigg.reaction":[
"ARAB_Lt"
],
"metanetx.reaction":[
"MNXR95913"
],
"sbo":"SBO:0000185"
}
},
{
"id":"ATPH1e",
"name":"ATP diphosphohydrolase",
"metabolites":{
"amp_e":1.0,
"atp_e":-1.0,
"h2o_e":-2.0,
"h_e":2.0,
"pi_e":2.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"957_AT1 or 954_AT2 or 956_AT1 or 954_AT1 or 953_AT1 or 955_AT1",
"subsystem":"Nucleotides",
"notes":{
"original_bigg_ids":[
"ATPH1e"
]
},
"annotation":{
"bigg.reaction":[
"ATPH1e"
],
"biocyc":[
"META:APYRASE-RXN"
],
"ec-code":[
"3.6.1.5"
],
"kegg.reaction":[
"R00085"
],
"metanetx.reaction":[
"MNXR96128"
],
"rhea":[
"20988",
"20990",
"20991",
"20989"
],
"sabiork":[
"670"
],
"sbo":"SBO:0000176",
"seed.reaction":[
"rxn00061"
]
}
},
{
"id":"ARACHCOAtx",
"name":"Fatty acid intracellular transport",
"metabolites":{
"arachcoa_c":-1.0,
"arachcoa_x":1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Peroxisomal",
"notes":{
"original_bigg_ids":[
"ARACHCOAtx"
]
},
"annotation":{
"bigg.reaction":[
"ARACHCOAtx"
],
"metanetx.reaction":[
"MNXR95914"
],
"sbo":"SBO:0000185"
}
},
{
"id":"ARGt4",
"name":"L-arginine transport in via sodium symport",
"metabolites":{
"arg__L_c":1.0,
"arg__L_e":-1.0,
"na1_c":1.0,
"na1_e":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"11254_AT1",
"subsystem":"Transport, Extracellular",
"notes":{
"original_bigg_ids":[
"ARGt4"
]
},
"annotation":{
"bigg.reaction":[
"ARGt4"
],
"metanetx.reaction":[
"MNXR95955"
],
"sbo":"SBO:0000185"
}
},
{
"id":"ARACHCPT1",
"name":"Carnitine transferase",
"metabolites":{
"arachcoa_c":-1.0,
"arachcrn_c":1.0,
"coa_c":1.0,
"crn_c":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"126129_AT1 or 1375_AT1 or 1375_AT3 or 1375_AT2 or 1374_AT1 or 1375_AT4",
"subsystem":"Carnitine shuttle",
"notes":{
"original_bigg_ids":[
"ARACHCPT1"
]
},
"annotation":{
"bigg.reaction":[
"ARACHCPT1"
],
"metanetx.reaction":[
"MNXR95915"
],
"sbo":"SBO:0000176"
}
},
{
"id":"ARACHCPT2",
"name":"Carnitine transferase",
"metabolites":{
"arachcoa_m":1.0,
"arachcrn_m":-1.0,
"coa_m":-1.0,
"crn_m":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"1376_AT1",
"subsystem":"Carnitine shuttle",
"notes":{
"original_bigg_ids":[
"ARACHCPT2"
]
},
"annotation":{
"bigg.reaction":[
"ARACHCPT2"
],
"metanetx.reaction":[
"MNXR95915"
],
"sbo":"SBO:0000176"
}
},
{
"id":"ATPH2e",
"name":"ATP diphosphohydrolase",
"metabolites":{
"adp_e":-1.0,
"amp_e":1.0,
"h2o_e":-1.0,
"h_e":1.0,
"pi_e":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"956_AT1 or 954_AT2 or 957_AT1 or 954_AT1 or 953_AT1 or 955_AT1",
"subsystem":"Nucleotides",
"notes":{
"original_bigg_ids":[
"ATPH2e"
]
},
"annotation":{
"bigg.reaction":[
"ATPH2e"
],
"biocyc":[
"META:RXN-10862"
],
"ec-code":[
"3.1.3",
"3.6.1.5",
"3.1.3.2",
"3.6.1.9",
"3.6.1.53",
"3.6.1.15"
],
"kegg.reaction":[
"R00122"
],
"metanetx.reaction":[
"MNXR96129"
],
"sabiork":[
"246"
],
"sbo":"SBO:0000176",
"seed.reaction":[
"rxn00092"
]
}
},
{
"id":"ATPS4m",
"name":"ATP synthase (four protons for one ATP)",
"metabolites":{
"adp_m":-1.0,
"atp_m":1.0,
"h2o_m":1.0,
"h_c":-4.0,
"h_m":3.0,
"pi_m":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"((522_AT2 and 9551_AT3 and 4905_AT1 and 10476_AT2 and 517_AT1 and 521_AT1 and 515_AT2 and 10632_AT1) or (515_AT3 and 10476_AT1 and 516_AT2 and 4905_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1 and 521_AT1) or (10476_AT1 and 518_AT2 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 522_AT3 and 515_AT2 and 521_AT1) or (522_AT5 and 4905_AT1 and 518_AT3 and 10476_AT1 and 515_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 522_AT1 and 515_AT3 and 10476_AT2 and 516_AT2 and 4905_AT1) or (522_AT1 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 10476_AT1 and 516_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 521_AT1 and 522_AT4 and 517_AT2) or (521_AT1 and 522_AT1 and 10632_AT1 and 516_AT2 and 4905_AT1 and 9551_AT3 and 515_AT3 and 10476_AT1) or (515_AT1 and 10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT1 and 10632_AT1 and 521_AT1 and 517_AT2) or (522_AT4 and 521_AT1 and 517_AT2 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 10476_AT1 and 515_AT1) or (522_AT1 and 517_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT2 and 515_AT3) or (521_AT1 and 522_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 518_AT3 and 515_AT1 and 10476_AT2) or (10632_AT1 and 515_AT2 and 521_AT1 and 517_AT2 and 10476_AT2 and 4905_AT1 and 9551_AT3 and 522_AT2) or (10476_AT1 and 515_AT1 and 522_AT2 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 517_AT1 and 521_AT1) or (4905_AT1 and 516_AT2 and 10476_AT2 and 521_AT1 and 515_AT2 and 9551_AT1 and 522_AT3 and 10632_AT1) or (10632_AT1 and 9551_AT1 and 518_AT1 and 521_AT1 and 10476_AT2 and 515_AT3 and 522_AT2 and 4905_AT1) or (9551_AT1 and 10632_AT1 and 522_AT3 and 521_AT1 and 517_AT2 and 10476_AT2 and 515_AT1 and 4905_AT1) or (10476_AT1 and 4905_AT1 and 516_AT2 and 10632_AT1 and 522_AT3 and 9551_AT1 and 521_AT1 and 515_AT2) or (10476_AT1 and 516_AT2 and 4905_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1 and 515_AT2 and 521_AT1) or (10632_AT1 and 522_AT4 and 515_AT2 and 521_AT1 and 518_AT3 and 10476_AT1 and 9551_AT3 and 4905_AT1) or (522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1 and 4905_AT1 and 10476_AT2 and 518_AT2 and 515_AT3) or (515_AT3 and 10476_AT1 and 516_AT2 and 4905_AT1 and 522_AT5 and 9551_AT2 and 10632_AT1 and 521_AT1) or (515_AT3 and 10476_AT2 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 521_AT1 and 522_AT1 and 517_AT2) or (521_AT1 and 515_AT2 and 518_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT5 and 10476_AT2) or (522_AT4 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT2 and 518_AT3 and 515_AT1) or (10476_AT2 and 516_AT1 and 515_AT3 and 4905_AT1 and 10632_AT1 and 9551_AT2 and 521_AT1 and 522_AT4) or (522_AT5 and 4905_AT1 and 10476_AT2 and 518_AT1 and 521_AT1 and 515_AT2 and 9551_AT2 and 10632_AT1) or (515_AT2 and 521_AT1 and 518_AT1 and 522_AT1 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 10476_AT2) or (521_AT1 and 10632_AT1 and 4905_AT1 and 522_AT5 and 9551_AT3 and 518_AT2 and 515_AT1 and 10476_AT2) or (9551_AT2 and 522_AT3 and 10632_AT1 and 521_AT1 and 10476_AT1 and 515_AT1 and 518_AT3 and 4905_AT1) or (9551_AT2 and 10632_AT1 and 518_AT1 and 521_AT1 and 10476_AT2 and 515_AT3 and 522_AT2 and 4905_AT1) or (521_AT1 and 522_AT4 and 517_AT2 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 515_AT3 and 10476_AT2) or (521_AT1 and 522_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 515_AT3 and 10476_AT2 and 518_AT3) or (4905_AT1 and 10476_AT2 and 518_AT2 and 515_AT3 and 521_AT1 and 10632_AT1 and 522_AT3 and 9551_AT1) or (9551_AT3 and 4905_AT1 and 10476_AT2 and 515_AT1 and 518_AT2 and 522_AT1 and 521_AT1 and 10632_AT1) or (10632_AT1 and 521_AT1 and 515_AT2 and 522_AT4 and 518_AT1 and 10476_AT1 and 4905_AT1 and 9551_AT3) or (515_AT2 and 521_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT5 and 516_AT1 and 10476_AT1) or (517_AT1 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT1 and 522_AT5 and 4905_AT1 and 10476_AT1) or (517_AT2 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5 and 4905_AT1 and 10476_AT1) or (518_AT3 and 10476_AT2 and 4905_AT1 and 522_AT3 and 10632_AT1 and 9551_AT1 and 515_AT2 and 521_AT1) or (521_AT1 and 10632_AT1 and 4905_AT1 and 522_AT5 and 516_AT2 and 9551_AT3 and 10476_AT2 and 515_AT1) or (522_AT3 and 10632_AT1 and 521_AT1 and 10476_AT1 and 515_AT1 and 516_AT2 and 4905_AT1 and 9551_AT3) or (522_AT5 and 4905_AT1 and 10476_AT1 and 515_AT1 and 518_AT3 and 521_AT1 and 9551_AT1 and 10632_AT1) or (9551_AT2 and 522_AT3 and 10632_AT1 and 521_AT1 and 517_AT2 and 515_AT1 and 10476_AT2 and 4905_AT1) or (10476_AT2 and 515_AT3 and 522_AT2 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 518_AT1 and 521_AT1) or (4905_AT1 and 9551_AT3 and 10476_AT1 and 515_AT2 and 521_AT1 and 517_AT2 and 522_AT3 and 10632_AT1) or (10476_AT2 and 9551_AT3 and 522_AT2 and 4905_AT1 and 10632_AT1 and 518_AT1 and 515_AT2 and 521_AT1) or (10476_AT1 and 515_AT3 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 517_AT1 and 521_AT1 and 522_AT4) or (10632_AT1 and 9551_AT1 and 518_AT1 and 521_AT1 and 515_AT1 and 10476_AT1 and 522_AT5 and 4905_AT1) or (4905_AT1 and 522_AT5 and 10476_AT1 and 516_AT1 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT2) or (9551_AT3 and 4905_AT1 and 10476_AT1 and 515_AT3 and 518_AT2 and 522_AT1 and 521_AT1 and 10632_AT1) or (9551_AT2 and 10632_AT1 and 517_AT1 and 515_AT2 and 521_AT1 and 10476_AT2 and 4905_AT1 and 522_AT5) or (10476_AT1 and 515_AT3 and 4905_AT1 and 522_AT3 and 10632_AT1 and 9551_AT1 and 517_AT2 and 521_AT1) or (4905_AT1 and 9551_AT3 and 515_AT3 and 10476_AT1 and 522_AT4 and 521_AT1 and 517_AT1 and 10632_AT1) or (10632_AT1 and 521_AT1 and 515_AT3 and 518_AT3 and 10476_AT1 and 4905_AT1 and 522_AT5 and 9551_AT3) or (515_AT1 and 10476_AT2 and 9551_AT3 and 522_AT2 and 4905_AT1 and 10632_AT1 and 518_AT1 and 521_AT1) or (4905_AT1 and 522_AT5 and 516_AT1 and 10476_AT2 and 515_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1) or (9551_AT3 and 4905_AT1 and 522_AT5 and 10476_AT1 and 515_AT3 and 518_AT1 and 521_AT1 and 10632_AT1) or (521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 522_AT2 and 518_AT2 and 515_AT1 and 10476_AT2) or (515_AT3 and 518_AT2 and 10476_AT2 and 522_AT5 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 521_AT1) or (515_AT1 and 10476_AT1 and 9551_AT3 and 522_AT2 and 4905_AT1 and 10632_AT1 and 517_AT1 and 521_AT1) or (4905_AT1 and 522_AT2 and 9551_AT3 and 10476_AT1 and 515_AT2 and 521_AT1 and 517_AT1 and 10632_AT1) or (521_AT1 and 9551_AT2 and 10632_AT1 and 522_AT5 and 4905_AT1 and 10476_AT2 and 515_AT1 and 516_AT1) or (9551_AT1 and 10632_AT1 and 522_AT3 and 521_AT1 and 518_AT1 and 515_AT1 and 10476_AT1 and 4905_AT1) or (515_AT1 and 10476_AT2 and 516_AT1 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 522_AT3 and 521_AT1) or (4905_AT1 and 10476_AT2 and 515_AT1 and 521_AT1 and 522_AT4 and 517_AT1 and 9551_AT1 and 10632_AT1) or (10476_AT1 and 516_AT1 and 4905_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1 and 521_AT1 and 515_AT2) or (521_AT1 and 9551_AT1 and 10632_AT1 and 522_AT5 and 4905_AT1 and 515_AT1 and 10476_AT2 and 516_AT1) or (521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 522_AT5 and 516_AT1 and 10476_AT2 and 515_AT3) or (521_AT1 and 10632_AT1 and 522_AT3 and 9551_AT3 and 4905_AT1 and 518_AT3 and 10476_AT2 and 515_AT3) or (9551_AT2 and 10632_AT1 and 521_AT1 and 516_AT1 and 10476_AT2 and 515_AT3 and 522_AT2 and 4905_AT1) or (515_AT1 and 10476_AT1 and 4905_AT1 and 522_AT5 and 9551_AT1 and 10632_AT1 and 521_AT1 and 517_AT1) or (521_AT1 and 9551_AT2 and 10632_AT1 and 522_AT2 and 516_AT2 and 4905_AT1 and 10476_AT1 and 515_AT3) or (4905_AT1 and 516_AT2 and 515_AT3 and 10476_AT1 and 521_AT1 and 522_AT4 and 9551_AT1 and 10632_AT1) or (10476_AT1 and 515_AT1 and 9551_AT3 and 4905_AT1 and 516_AT2 and 10632_AT1 and 521_AT1 and 522_AT4) or (521_AT1 and 522_AT4 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT2 and 516_AT1 and 515_AT3) or (4905_AT1 and 518_AT2 and 10476_AT1 and 515_AT2 and 521_AT1 and 522_AT1 and 9551_AT2 and 10632_AT1) or (10632_AT1 and 521_AT1 and 522_AT4 and 518_AT1 and 515_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT3) or (515_AT1 and 518_AT3 and 10476_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 521_AT1 and 522_AT4) or (522_AT4 and 521_AT1 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 10476_AT1 and 518_AT2 and 515_AT3) or (515_AT1 and 10476_AT2 and 4905_AT1 and 522_AT5 and 516_AT2 and 10632_AT1 and 9551_AT1 and 521_AT1) or (10632_AT1 and 9551_AT1 and 522_AT1 and 521_AT1 and 10476_AT2 and 515_AT1 and 516_AT1 and 4905_AT1) or (522_AT5 and 4905_AT1 and 9551_AT3 and 515_AT3 and 10476_AT2 and 521_AT1 and 517_AT2 and 10632_AT1) or (521_AT1 and 522_AT1 and 517_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 515_AT1 and 10476_AT2) or (9551_AT3 and 4905_AT1 and 10476_AT2 and 518_AT2 and 515_AT3 and 521_AT1 and 522_AT3 and 10632_AT1) or (515_AT3 and 518_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1 and 521_AT1) or (10476_AT2 and 518_AT2 and 515_AT3 and 9551_AT3 and 4905_AT1 and 522_AT5 and 10632_AT1 and 521_AT1) or (10632_AT1 and 521_AT1 and 517_AT2 and 515_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT3 and 522_AT2) or (4905_AT1 and 516_AT2 and 10476_AT1 and 515_AT1 and 521_AT1 and 522_AT4 and 10632_AT1 and 9551_AT1) or (10476_AT2 and 4905_AT1 and 516_AT2 and 522_AT2 and 10632_AT1 and 9551_AT2 and 521_AT1 and 515_AT2) or (521_AT1 and 517_AT2 and 522_AT3 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 515_AT3 and 10476_AT1) or (9551_AT2 and 10632_AT1 and 517_AT2 and 521_AT1 and 522_AT4 and 515_AT1 and 10476_AT2 and 4905_AT1) or (10476_AT2 and 522_AT5 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2 and 517_AT1) or (518_AT1 and 521_AT1 and 522_AT3 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT1 and 515_AT1) or (521_AT1 and 10632_AT1 and 4905_AT1 and 522_AT5 and 9551_AT3 and 515_AT1 and 518_AT3 and 10476_AT2) or (10476_AT2 and 515_AT1 and 4905_AT1 and 9551_AT3 and 522_AT3 and 10632_AT1 and 521_AT1 and 517_AT2) or (9551_AT2 and 10632_AT1 and 521_AT1 and 515_AT3 and 10476_AT1 and 518_AT3 and 4905_AT1 and 522_AT2) or (4905_AT1 and 515_AT1 and 10476_AT1 and 518_AT1 and 522_AT4 and 521_AT1 and 10632_AT1 and 9551_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 522_AT4 and 521_AT1 and 518_AT1) or (10632_AT1 and 518_AT1 and 521_AT1 and 10476_AT1 and 515_AT3 and 522_AT2 and 9551_AT3 and 4905_AT1) or (9551_AT2 and 10632_AT1 and 517_AT1 and 515_AT2 and 521_AT1 and 10476_AT1 and 522_AT2 and 4905_AT1) or (4905_AT1 and 522_AT5 and 518_AT2 and 10476_AT2 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT2) or (9551_AT2 and 522_AT3 and 10632_AT1 and 515_AT2 and 521_AT1 and 10476_AT2 and 516_AT2 and 4905_AT1) or (515_AT3 and 10476_AT1 and 516_AT1 and 4905_AT1 and 522_AT2 and 9551_AT1 and 10632_AT1 and 521_AT1) or (522_AT1 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 516_AT1 and 10476_AT2) or (10476_AT1 and 4905_AT1 and 9551_AT3 and 522_AT3 and 10632_AT1 and 515_AT2 and 521_AT1 and 517_AT1) or (516_AT1 and 10476_AT1 and 515_AT1 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 522_AT3 and 521_AT1) or (521_AT1 and 517_AT1 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 522_AT5 and 515_AT1 and 10476_AT1) or (10476_AT1 and 4905_AT1 and 522_AT5 and 9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2 and 518_AT1) or (10476_AT1 and 9551_AT3 and 4905_AT1 and 522_AT5 and 516_AT2 and 10632_AT1 and 521_AT1 and 515_AT2) or (521_AT1 and 10632_AT1 and 516_AT2 and 4905_AT1 and 522_AT2 and 9551_AT3 and 515_AT3 and 10476_AT1) or (9551_AT1 and 10632_AT1 and 522_AT3 and 515_AT2 and 521_AT1 and 518_AT2 and 10476_AT2 and 4905_AT1) or (10476_AT1 and 515_AT3 and 4905_AT1 and 522_AT5 and 10632_AT1 and 9551_AT1 and 517_AT1 and 521_AT1) or (522_AT4 and 521_AT1 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 518_AT2 and 515_AT3 and 10476_AT2) or (522_AT5 and 4905_AT1 and 518_AT3 and 10476_AT2 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT1) or (10476_AT2 and 516_AT2 and 4905_AT1 and 522_AT2 and 9551_AT3 and 10632_AT1 and 515_AT2 and 521_AT1) or (522_AT1 and 521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 516_AT2 and 515_AT1 and 10476_AT2) or (9551_AT2 and 10632_AT1 and 521_AT1 and 10476_AT1 and 515_AT3 and 518_AT2 and 522_AT5 and 4905_AT1) or (10632_AT1 and 521_AT1 and 516_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT2 and 4905_AT1) or (4905_AT1 and 10476_AT2 and 516_AT1 and 522_AT1 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT2) or (4905_AT1 and 515_AT1 and 10476_AT2 and 518_AT3 and 522_AT4 and 521_AT1 and 9551_AT2 and 10632_AT1) or (515_AT3 and 10476_AT2 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 522_AT3 and 521_AT1 and 517_AT2) or (521_AT1 and 9551_AT1 and 10632_AT1 and 522_AT3 and 4905_AT1 and 515_AT3 and 10476_AT2 and 518_AT3) or (10632_AT1 and 518_AT1 and 521_AT1 and 515_AT2 and 10476_AT1 and 9551_AT3 and 4905_AT1 and 522_AT5) or (9551_AT3 and 522_AT2 and 4905_AT1 and 10476_AT2 and 515_AT3 and 518_AT2 and 521_AT1 and 10632_AT1) or (10632_AT1 and 521_AT1 and 522_AT1 and 516_AT1 and 515_AT1 and 10476_AT1 and 4905_AT1 and 9551_AT3) or (517_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1 and 522_AT2 and 4905_AT1 and 515_AT1 and 10476_AT2) or (10632_AT1 and 9551_AT2 and 522_AT4 and 521_AT1 and 517_AT1 and 515_AT3 and 10476_AT2 and 4905_AT1) or (522_AT1 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT1 and 518_AT2) or (4905_AT1 and 522_AT2 and 518_AT2 and 515_AT3 and 10476_AT2 and 521_AT1 and 9551_AT1 and 10632_AT1) or (4905_AT1 and 522_AT2 and 9551_AT3 and 518_AT3 and 515_AT1 and 10476_AT2 and 521_AT1 and 10632_AT1) or (4905_AT1 and 515_AT3 and 10476_AT1 and 518_AT3 and 521_AT1 and 522_AT1 and 9551_AT1 and 10632_AT1) or (521_AT1 and 10632_AT1 and 522_AT2 and 9551_AT3 and 4905_AT1 and 516_AT2 and 10476_AT2 and 515_AT3) or (10632_AT1 and 9551_AT2 and 521_AT1 and 515_AT2 and 10476_AT1 and 516_AT1 and 4905_AT1 and 522_AT2) or (521_AT1 and 515_AT2 and 10632_AT1 and 522_AT2 and 9551_AT3 and 4905_AT1 and 10476_AT2 and 516_AT1) or (521_AT1 and 522_AT4 and 518_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 515_AT3 and 10476_AT2) or (515_AT2 and 521_AT1 and 522_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 518_AT3 and 10476_AT1) or (522_AT2 and 4905_AT1 and 10476_AT1 and 515_AT1 and 518_AT3 and 521_AT1 and 9551_AT2 and 10632_AT1) or (521_AT1 and 515_AT2 and 522_AT1 and 10632_AT1 and 4905_AT1 and 516_AT2 and 9551_AT3 and 10476_AT2) or (522_AT4 and 515_AT2 and 521_AT1 and 517_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 10476_AT2) or (10476_AT1 and 515_AT1 and 522_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 517_AT1 and 521_AT1) or (9551_AT3 and 4905_AT1 and 10476_AT2 and 515_AT3 and 518_AT1 and 521_AT1 and 522_AT4 and 10632_AT1) or (10476_AT2 and 515_AT3 and 4905_AT1 and 522_AT3 and 10632_AT1 and 9551_AT1 and 518_AT1 and 521_AT1) or (516_AT2 and 4905_AT1 and 10476_AT2 and 515_AT2 and 521_AT1 and 522_AT1 and 9551_AT1 and 10632_AT1) or (10476_AT2 and 518_AT2 and 4905_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1 and 515_AT2 and 521_AT1) or (10476_AT1 and 4905_AT1 and 522_AT5 and 10632_AT1 and 9551_AT2 and 517_AT2 and 515_AT2 and 521_AT1) or (4905_AT1 and 522_AT2 and 9551_AT3 and 515_AT3 and 10476_AT2 and 521_AT1 and 517_AT2 and 10632_AT1) or (518_AT1 and 521_AT1 and 515_AT2 and 9551_AT2 and 10632_AT1 and 522_AT2 and 4905_AT1 and 10476_AT1) or (516_AT1 and 10476_AT2 and 515_AT1 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 522_AT4 and 521_AT1) or (10476_AT1 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 517_AT1 and 521_AT1 and 522_AT4 and 515_AT2) or (521_AT1 and 522_AT3 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 515_AT3 and 518_AT2 and 10476_AT1) or (10476_AT1 and 9551_AT3 and 4905_AT1 and 516_AT2 and 522_AT3 and 10632_AT1 and 521_AT1 and 515_AT2) or (9551_AT3 and 4905_AT1 and 522_AT5 and 10476_AT2 and 515_AT3 and 517_AT1 and 521_AT1 and 10632_AT1) or (522_AT2 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1) or (518_AT1 and 521_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1 and 4905_AT1 and 515_AT1 and 10476_AT1) or (521_AT1 and 515_AT2 and 10632_AT1 and 4905_AT1 and 522_AT2 and 9551_AT3 and 518_AT3 and 10476_AT2) or (10476_AT1 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 515_AT2 and 521_AT1 and 518_AT1 and 522_AT1) or (4905_AT1 and 515_AT1 and 10476_AT1 and 518_AT3 and 522_AT4 and 521_AT1 and 9551_AT2 and 10632_AT1) or (10476_AT2 and 515_AT1 and 522_AT2 and 4905_AT1 and 516_AT2 and 10632_AT1 and 9551_AT1 and 521_AT1) or (9551_AT2 and 10632_AT1 and 517_AT2 and 522_AT4 and 515_AT2 and 521_AT1 and 10476_AT2 and 4905_AT1) or (522_AT5 and 4905_AT1 and 518_AT3 and 10476_AT2 and 515_AT1 and 521_AT1 and 9551_AT1 and 10632_AT1) or (4905_AT1 and 522_AT2 and 518_AT3 and 10476_AT2 and 515_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 10476_AT1 and 518_AT3 and 515_AT3 and 521_AT1 and 522_AT4 and 10632_AT1 and 9551_AT1) or (10632_AT1 and 9551_AT1 and 517_AT1 and 521_AT1 and 515_AT2 and 10476_AT1 and 522_AT2 and 4905_AT1) or (10632_AT1 and 9551_AT2 and 522_AT4 and 515_AT2 and 521_AT1 and 516_AT1 and 10476_AT2 and 4905_AT1) or (10476_AT1 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 522_AT3 and 518_AT1 and 515_AT2 and 521_AT1) or (521_AT1 and 517_AT2 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 522_AT2 and 515_AT1 and 10476_AT1) or (9551_AT2 and 522_AT3 and 10632_AT1 and 517_AT2 and 521_AT1 and 10476_AT2 and 515_AT3 and 4905_AT1) or (10476_AT2 and 515_AT1 and 518_AT3 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 522_AT1 and 521_AT1) or (521_AT1 and 515_AT2 and 10632_AT1 and 522_AT5 and 4905_AT1 and 516_AT2 and 9551_AT3 and 10476_AT2) or (521_AT1 and 518_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT2 and 515_AT3 and 10476_AT1) or (4905_AT1 and 518_AT2 and 515_AT1 and 10476_AT1 and 521_AT1 and 522_AT1 and 9551_AT1 and 10632_AT1) or (4905_AT1 and 522_AT2 and 515_AT3 and 10476_AT1 and 518_AT3 and 521_AT1 and 9551_AT1 and 10632_AT1) or (4905_AT1 and 522_AT2 and 515_AT3 and 10476_AT1 and 521_AT1 and 518_AT1 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 10476_AT2 and 515_AT1 and 517_AT1 and 522_AT1 and 521_AT1 and 9551_AT2 and 10632_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 522_AT5 and 9551_AT2 and 10632_AT1 and 521_AT1 and 518_AT1) or (10632_AT1 and 522_AT4 and 521_AT1 and 10476_AT1 and 518_AT3 and 515_AT3 and 9551_AT3 and 4905_AT1) or (522_AT5 and 4905_AT1 and 10476_AT2 and 517_AT2 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT1) or (4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT3 and 522_AT4 and 521_AT1 and 10632_AT1 and 9551_AT1) or (4905_AT1 and 10476_AT2 and 515_AT1 and 522_AT1 and 517_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2) or (10632_AT1 and 521_AT1 and 522_AT4 and 518_AT2 and 515_AT1 and 10476_AT1 and 4905_AT1 and 9551_AT3) or (10476_AT1 and 518_AT2 and 4905_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1 and 515_AT2 and 521_AT1) or (10632_AT1 and 521_AT1 and 10476_AT2 and 518_AT3 and 515_AT3 and 522_AT2 and 9551_AT3 and 4905_AT1) or (518_AT2 and 10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT2 and 10632_AT1 and 515_AT2 and 521_AT1) or (10632_AT1 and 521_AT1 and 10476_AT2 and 518_AT3 and 515_AT3 and 9551_AT3 and 4905_AT1 and 522_AT5) or (10476_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 522_AT1 and 518_AT1 and 521_AT1 and 515_AT2) or (4905_AT1 and 10476_AT1 and 518_AT3 and 515_AT3 and 522_AT4 and 521_AT1 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 522_AT1 and 517_AT2 and 9551_AT1 and 10632_AT1) or (522_AT5 and 4905_AT1 and 516_AT2 and 10476_AT2 and 521_AT1 and 515_AT2 and 9551_AT1 and 10632_AT1) or (4905_AT1 and 522_AT5 and 10476_AT1 and 515_AT3 and 518_AT2 and 521_AT1 and 10632_AT1 and 9551_AT1) or (10476_AT2 and 515_AT3 and 9551_AT3 and 522_AT2 and 4905_AT1 and 10632_AT1 and 517_AT1 and 521_AT1) or (4905_AT1 and 522_AT2 and 9551_AT3 and 10476_AT1 and 521_AT1 and 515_AT2 and 517_AT2 and 10632_AT1) or (522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 515_AT1 and 10476_AT1 and 518_AT3) or (4905_AT1 and 9551_AT3 and 515_AT1 and 10476_AT2 and 521_AT1 and 517_AT2 and 522_AT1 and 10632_AT1) or (522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 516_AT2 and 10476_AT2 and 515_AT1) or (4905_AT1 and 516_AT1 and 10476_AT2 and 522_AT4 and 515_AT2 and 521_AT1 and 9551_AT1 and 10632_AT1) or (515_AT2 and 522_AT4 and 521_AT1 and 9551_AT1 and 10632_AT1 and 516_AT2 and 4905_AT1 and 10476_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 517_AT1 and 515_AT3 and 10476_AT1 and 4905_AT1 and 522_AT2) or (517_AT1 and 521_AT1 and 9551_AT2 and 10632_AT1 and 522_AT2 and 4905_AT1 and 10476_AT2 and 515_AT1) or (521_AT1 and 515_AT2 and 522_AT1 and 517_AT2 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 10476_AT2) or (9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2 and 10476_AT1 and 4905_AT1 and 522_AT5 and 516_AT2) or (4905_AT1 and 518_AT3 and 10476_AT2 and 515_AT3 and 522_AT4 and 521_AT1 and 10632_AT1 and 9551_AT1) or (521_AT1 and 517_AT2 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 522_AT5 and 515_AT3 and 10476_AT2) or (521_AT1 and 522_AT4 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 515_AT3 and 10476_AT2 and 516_AT1) or (4905_AT1 and 10476_AT2 and 515_AT1 and 518_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1) or (4905_AT1 and 10476_AT1 and 518_AT2 and 521_AT1 and 522_AT4 and 515_AT2 and 9551_AT2 and 10632_AT1) or (521_AT1 and 515_AT2 and 10632_AT1 and 522_AT3 and 4905_AT1 and 9551_AT3 and 518_AT3 and 10476_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2 and 10476_AT2 and 4905_AT1 and 516_AT2 and 522_AT2) or (515_AT1 and 10476_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT2 and 522_AT1 and 517_AT1 and 521_AT1) or (10632_AT1 and 522_AT1 and 515_AT2 and 521_AT1 and 10476_AT2 and 518_AT2 and 9551_AT3 and 4905_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 521_AT1 and 522_AT1 and 517_AT1) or (4905_AT1 and 516_AT2 and 10476_AT1 and 521_AT1 and 515_AT2 and 522_AT1 and 9551_AT2 and 10632_AT1) or (518_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 522_AT4 and 515_AT2 and 521_AT1) or (521_AT1 and 522_AT4 and 515_AT2 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 516_AT2 and 10476_AT2) or (9551_AT3 and 4905_AT1 and 10476_AT1 and 516_AT1 and 521_AT1 and 515_AT2 and 10632_AT1 and 522_AT3) or (9551_AT3 and 4905_AT1 and 522_AT5 and 10476_AT2 and 518_AT1 and 521_AT1 and 515_AT2 and 10632_AT1) or (9551_AT3 and 4905_AT1 and 522_AT5 and 10476_AT1 and 517_AT1 and 515_AT2 and 521_AT1 and 10632_AT1) or (515_AT1 and 10476_AT1 and 522_AT5 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 517_AT2 and 521_AT1) or (516_AT1 and 10476_AT2 and 4905_AT1 and 522_AT3 and 10632_AT1 and 9551_AT1 and 515_AT2 and 521_AT1) or (4905_AT1 and 9551_AT3 and 10476_AT2 and 521_AT1 and 515_AT2 and 517_AT2 and 522_AT3 and 10632_AT1) or (521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT1 and 522_AT2 and 4905_AT1 and 10476_AT2 and 516_AT1) or (518_AT2 and 515_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 521_AT1 and 522_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 517_AT2 and 10476_AT2 and 515_AT1 and 4905_AT1 and 522_AT2) or (521_AT1 and 517_AT1 and 9551_AT1 and 522_AT3 and 10632_AT1 and 4905_AT1 and 515_AT3 and 10476_AT1) or (9551_AT3 and 4905_AT1 and 515_AT1 and 10476_AT2 and 518_AT2 and 522_AT4 and 521_AT1 and 10632_AT1) or (522_AT4 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT1 and 4905_AT1 and 518_AT3 and 10476_AT2) or (516_AT1 and 10476_AT2 and 4905_AT1 and 522_AT5 and 9551_AT1 and 10632_AT1 and 515_AT2 and 521_AT1) or (515_AT3 and 10476_AT2 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 522_AT3 and 521_AT1 and 517_AT1) or (515_AT3 and 518_AT2 and 10476_AT1 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 521_AT1 and 522_AT1) or (10476_AT1 and 515_AT1 and 4905_AT1 and 10632_AT1 and 522_AT3 and 9551_AT1 and 517_AT1 and 521_AT1) or (10632_AT1 and 515_AT2 and 521_AT1 and 516_AT1 and 10476_AT2 and 522_AT5 and 4905_AT1 and 9551_AT3) or (521_AT1 and 10632_AT1 and 522_AT2 and 9551_AT3 and 4905_AT1 and 516_AT1 and 515_AT1 and 10476_AT2) or (10632_AT1 and 521_AT1 and 517_AT1 and 515_AT3 and 10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT3) or (9551_AT2 and 10632_AT1 and 517_AT1 and 521_AT1 and 10476_AT2 and 515_AT1 and 4905_AT1 and 522_AT5) or (522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT1) or (10476_AT1 and 515_AT1 and 518_AT3 and 4905_AT1 and 522_AT5 and 9551_AT2 and 10632_AT1 and 521_AT1) or (515_AT3 and 516_AT1 and 10476_AT1 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 522_AT4 and 521_AT1) or (10632_AT1 and 522_AT1 and 521_AT1 and 10476_AT1 and 515_AT1 and 518_AT2 and 9551_AT3 and 4905_AT1) or (522_AT3 and 10632_AT1 and 521_AT1 and 515_AT2 and 10476_AT2 and 518_AT2 and 9551_AT3 and 4905_AT1) or (10632_AT1 and 9551_AT2 and 522_AT3 and 517_AT2 and 521_AT1 and 10476_AT1 and 515_AT3 and 4905_AT1) or (521_AT1 and 10632_AT1 and 9551_AT1 and 522_AT5 and 4905_AT1 and 10476_AT2 and 515_AT3 and 518_AT2) or (10632_AT1 and 9551_AT1 and 517_AT1 and 521_AT1 and 522_AT4 and 10476_AT1 and 515_AT1 and 4905_AT1) or (518_AT3 and 10476_AT2 and 515_AT3 and 4905_AT1 and 522_AT5 and 10632_AT1 and 9551_AT1 and 521_AT1) or (4905_AT1 and 10476_AT1 and 515_AT3 and 517_AT1 and 522_AT1 and 521_AT1 and 9551_AT2 and 10632_AT1) or (521_AT1 and 9551_AT1 and 522_AT3 and 10632_AT1 and 4905_AT1 and 515_AT3 and 516_AT1 and 10476_AT2) or (10476_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 522_AT1 and 518_AT1 and 521_AT1 and 515_AT2) or (4905_AT1 and 515_AT3 and 10476_AT1 and 521_AT1 and 517_AT2 and 522_AT1 and 9551_AT2 and 10632_AT1) or (9551_AT3 and 4905_AT1 and 516_AT1 and 515_AT1 and 10476_AT1 and 522_AT4 and 521_AT1 and 10632_AT1) or (521_AT1 and 517_AT1 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 522_AT2 and 515_AT3 and 10476_AT1) or (521_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1 and 516_AT2 and 4905_AT1 and 10476_AT2 and 515_AT3) or (10632_AT1 and 521_AT1 and 522_AT4 and 10476_AT1 and 518_AT3 and 515_AT1 and 4905_AT1 and 9551_AT3) or (10476_AT2 and 518_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 522_AT1 and 515_AT2 and 521_AT1) or (10632_AT1 and 522_AT3 and 9551_AT1 and 517_AT1 and 521_AT1 and 515_AT2 and 10476_AT2 and 4905_AT1) or (521_AT1 and 10632_AT1 and 522_AT3 and 9551_AT1 and 4905_AT1 and 10476_AT1 and 516_AT1 and 515_AT3) or (9551_AT2 and 522_AT3 and 10632_AT1 and 521_AT1 and 515_AT2 and 517_AT2 and 10476_AT2 and 4905_AT1) or (515_AT2 and 521_AT1 and 517_AT2 and 9551_AT1 and 522_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1) or (10476_AT2 and 515_AT3 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 517_AT1 and 522_AT4 and 521_AT1) or (515_AT3 and 10476_AT2 and 4905_AT1 and 516_AT2 and 9551_AT1 and 522_AT3 and 10632_AT1 and 521_AT1) or (521_AT1 and 10632_AT1 and 4905_AT1 and 522_AT2 and 9551_AT3 and 516_AT1 and 10476_AT1 and 515_AT1) or (9551_AT2 and 10632_AT1 and 521_AT1 and 522_AT1 and 515_AT3 and 518_AT3 and 10476_AT1 and 4905_AT1) or (515_AT3 and 10476_AT2 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 521_AT1 and 522_AT1 and 517_AT1) or (521_AT1 and 522_AT3 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 518_AT3 and 10476_AT2 and 515_AT1) or (10632_AT1 and 9551_AT1 and 521_AT1 and 522_AT4 and 10476_AT1 and 515_AT1 and 518_AT2 and 4905_AT1) or (515_AT3 and 10476_AT2 and 522_AT5 and 4905_AT1 and 516_AT2 and 9551_AT3 and 10632_AT1 and 521_AT1) or (9551_AT2 and 10632_AT1 and 522_AT1 and 517_AT2 and 521_AT1 and 10476_AT2 and 515_AT3 and 4905_AT1) or (9551_AT2 and 10632_AT1 and 521_AT1 and 522_AT4 and 515_AT1 and 10476_AT1 and 4905_AT1 and 516_AT2) or (521_AT1 and 517_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT5 and 515_AT3 and 10476_AT2) or (517_AT1 and 522_AT1 and 515_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 10476_AT1) or (521_AT1 and 10632_AT1 and 9551_AT1 and 522_AT2 and 4905_AT1 and 10476_AT1 and 515_AT1 and 518_AT2) or (10476_AT2 and 515_AT1 and 4905_AT1 and 10632_AT1 and 522_AT3 and 9551_AT1 and 517_AT1 and 521_AT1) or (521_AT1 and 522_AT1 and 518_AT1 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 515_AT3 and 10476_AT1) or (10476_AT2 and 515_AT1 and 9551_AT3 and 4905_AT1 and 522_AT3 and 10632_AT1 and 517_AT1 and 521_AT1) or (10632_AT1 and 9551_AT1 and 517_AT2 and 522_AT1 and 515_AT2 and 521_AT1 and 10476_AT2 and 4905_AT1) or (521_AT1 and 515_AT2 and 517_AT2 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT5 and 10476_AT1) or (4905_AT1 and 515_AT1 and 10476_AT1 and 517_AT1 and 521_AT1 and 10632_AT1 and 9551_AT2 and 522_AT3) or (4905_AT1 and 516_AT2 and 9551_AT3 and 522_AT2 and 10476_AT1 and 521_AT1 and 515_AT2 and 10632_AT1) or (522_AT5 and 4905_AT1 and 10476_AT1 and 518_AT1 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2) or (517_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5 and 4905_AT1 and 515_AT1 and 10476_AT2) or (4905_AT1 and 522_AT2 and 518_AT3 and 515_AT1 and 10476_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1) or (10476_AT2 and 4905_AT1 and 522_AT2 and 9551_AT1 and 10632_AT1 and 515_AT2 and 521_AT1 and 518_AT1) or (521_AT1 and 522_AT4 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 516_AT2 and 10476_AT2 and 515_AT1) or (4905_AT1 and 10476_AT1 and 517_AT1 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT2 and 522_AT3) or (522_AT3 and 10632_AT1 and 521_AT1 and 515_AT2 and 518_AT3 and 10476_AT2 and 9551_AT3 and 4905_AT1) or (516_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 4905_AT1 and 522_AT3 and 10632_AT1 and 521_AT1) or (4905_AT1 and 515_AT1 and 10476_AT1 and 518_AT3 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT2) or (10476_AT1 and 516_AT2 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 515_AT2 and 522_AT4 and 521_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 522_AT4 and 521_AT1 and 518_AT1) or (522_AT4 and 521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 515_AT3 and 518_AT3 and 10476_AT2) or (515_AT1 and 10476_AT1 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 522_AT1 and 518_AT1 and 521_AT1) or (4905_AT1 and 518_AT3 and 10476_AT1 and 521_AT1 and 515_AT2 and 9551_AT2 and 522_AT3 and 10632_AT1) or (10476_AT2 and 4905_AT1 and 522_AT5 and 10632_AT1 and 9551_AT2 and 517_AT2 and 515_AT2 and 521_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 516_AT2 and 10632_AT1 and 9551_AT2 and 521_AT1 and 522_AT4) or (4905_AT1 and 515_AT3 and 10476_AT2 and 518_AT3 and 521_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1) or (9551_AT2 and 10632_AT1 and 518_AT1 and 522_AT1 and 521_AT1 and 10476_AT2 and 515_AT3 and 4905_AT1) or (522_AT3 and 10632_AT1 and 515_AT2 and 521_AT1 and 518_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT3) or (521_AT1 and 9551_AT2 and 10632_AT1 and 522_AT3 and 516_AT2 and 4905_AT1 and 515_AT1 and 10476_AT2) or (515_AT3 and 10476_AT1 and 4905_AT1 and 516_AT2 and 9551_AT1 and 10632_AT1 and 521_AT1 and 522_AT1) or (518_AT2 and 10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2) or (10476_AT2 and 515_AT1 and 522_AT2 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 517_AT1 and 521_AT1) or (9551_AT2 and 10632_AT1 and 521_AT1 and 517_AT1 and 515_AT3 and 10476_AT2 and 522_AT5 and 4905_AT1) or (521_AT1 and 515_AT2 and 518_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT2 and 10476_AT1) or (9551_AT2 and 10632_AT1 and 522_AT3 and 518_AT1 and 521_AT1 and 515_AT2 and 10476_AT1 and 4905_AT1) or (521_AT1 and 9551_AT1 and 10632_AT1 and 522_AT3 and 516_AT2 and 4905_AT1 and 10476_AT1 and 515_AT1) or (10476_AT2 and 515_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT2 and 518_AT1 and 522_AT4 and 521_AT1) or (10476_AT1 and 515_AT3 and 522_AT2 and 516_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 521_AT1) or (521_AT1 and 522_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 515_AT3 and 10476_AT1 and 516_AT1) or (515_AT1 and 10476_AT1 and 518_AT2 and 9551_AT3 and 4905_AT1 and 522_AT3 and 10632_AT1 and 521_AT1) or (521_AT1 and 515_AT2 and 522_AT3 and 10632_AT1 and 9551_AT1 and 4905_AT1 and 10476_AT1 and 516_AT1) or (522_AT4 and 515_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1) or (521_AT1 and 522_AT3 and 10632_AT1 and 9551_AT1 and 4905_AT1 and 515_AT1 and 10476_AT2 and 518_AT3) or (521_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 518_AT2 and 515_AT1 and 10476_AT1) or (10476_AT1 and 515_AT1 and 518_AT2 and 4905_AT1 and 10632_AT1 and 522_AT3 and 9551_AT1 and 521_AT1) or (516_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 522_AT3 and 515_AT2 and 521_AT1) or (4905_AT1 and 522_AT2 and 516_AT1 and 515_AT1 and 10476_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1) or (521_AT1 and 515_AT2 and 10632_AT1 and 522_AT3 and 4905_AT1 and 516_AT2 and 9551_AT3 and 10476_AT2) or (522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT3) or (10632_AT1 and 9551_AT2 and 515_AT2 and 521_AT1 and 517_AT1 and 10476_AT2 and 4905_AT1 and 522_AT2) or (521_AT1 and 515_AT2 and 9551_AT1 and 522_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 518_AT3) or (4905_AT1 and 10476_AT1 and 521_AT1 and 515_AT2 and 517_AT1 and 9551_AT1 and 522_AT3 and 10632_AT1) or (10632_AT1 and 522_AT1 and 517_AT2 and 521_AT1 and 515_AT1 and 10476_AT1 and 9551_AT3 and 4905_AT1) or (521_AT1 and 9551_AT2 and 10632_AT1 and 522_AT2 and 4905_AT1 and 516_AT1 and 515_AT1 and 10476_AT1) or (9551_AT1 and 522_AT3 and 10632_AT1 and 521_AT1 and 515_AT3 and 10476_AT1 and 516_AT2 and 4905_AT1) or (10632_AT1 and 522_AT3 and 517_AT1 and 521_AT1 and 10476_AT2 and 515_AT3 and 9551_AT3 and 4905_AT1) or (515_AT1 and 10476_AT1 and 4905_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1 and 517_AT2 and 521_AT1) or (4905_AT1 and 10476_AT2 and 515_AT1 and 517_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1) or (4905_AT1 and 522_AT2 and 515_AT3 and 10476_AT2 and 521_AT1 and 517_AT1 and 9551_AT1 and 10632_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 522_AT4 and 515_AT2 and 517_AT2 and 10476_AT1 and 4905_AT1) or (10476_AT2 and 4905_AT1 and 522_AT2 and 10632_AT1 and 9551_AT2 and 521_AT1 and 515_AT2 and 518_AT1) or (517_AT1 and 521_AT1 and 515_AT2 and 522_AT3 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT2) or (515_AT1 and 10476_AT1 and 516_AT2 and 4905_AT1 and 522_AT5 and 9551_AT3 and 10632_AT1 and 521_AT1) or (515_AT2 and 521_AT1 and 517_AT1 and 522_AT1 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 10476_AT2) or (521_AT1 and 522_AT3 and 10632_AT1 and 9551_AT1 and 4905_AT1 and 518_AT3 and 10476_AT1 and 515_AT3) or (10476_AT1 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 517_AT2 and 521_AT1 and 515_AT2 and 522_AT4) or (522_AT3 and 10632_AT1 and 521_AT1 and 10476_AT2 and 515_AT3 and 9551_AT3 and 4905_AT1 and 516_AT2) or (521_AT1 and 515_AT2 and 522_AT1 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 10476_AT1 and 518_AT3) or (9551_AT1 and 522_AT3 and 10632_AT1 and 521_AT1 and 515_AT2 and 518_AT1 and 10476_AT1 and 4905_AT1) or (4905_AT1 and 518_AT3 and 10476_AT2 and 521_AT1 and 515_AT2 and 9551_AT2 and 10632_AT1 and 522_AT3) or (517_AT2 and 522_AT4 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT2) or (517_AT2 and 522_AT4 and 521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 515_AT1 and 10476_AT1) or (10476_AT2 and 515_AT1 and 516_AT2 and 4905_AT1 and 522_AT2 and 9551_AT2 and 10632_AT1 and 521_AT1) or (518_AT2 and 10476_AT1 and 515_AT1 and 4905_AT1 and 522_AT5 and 9551_AT3 and 10632_AT1 and 521_AT1) or (518_AT1 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 515_AT1 and 10476_AT2) or (521_AT1 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 522_AT2 and 515_AT3 and 518_AT2 and 10476_AT1) or (4905_AT1 and 10476_AT2 and 515_AT1 and 517_AT1 and 522_AT4 and 521_AT1 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 522_AT2 and 10476_AT2 and 515_AT2 and 521_AT1 and 517_AT2 and 9551_AT1 and 10632_AT1) or (515_AT3 and 10476_AT2 and 4905_AT1 and 522_AT5 and 9551_AT1 and 10632_AT1 and 521_AT1 and 517_AT2) or (521_AT1 and 515_AT2 and 522_AT4 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 10476_AT2 and 516_AT1) or (515_AT1 and 10476_AT1 and 522_AT5 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 518_AT1 and 521_AT1) or (521_AT1 and 10632_AT1 and 9551_AT2 and 522_AT5 and 4905_AT1 and 516_AT2 and 10476_AT1 and 515_AT1) or (522_AT1 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT1 and 4905_AT1 and 516_AT2 and 10476_AT1) or (10476_AT2 and 515_AT3 and 4905_AT1 and 522_AT3 and 10632_AT1 and 9551_AT1 and 517_AT2 and 521_AT1) or (521_AT1 and 522_AT4 and 517_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 515_AT3 and 10476_AT1) or (522_AT2 and 9551_AT3 and 4905_AT1 and 515_AT1 and 10476_AT2 and 518_AT2 and 521_AT1 and 10632_AT1) or (9551_AT3 and 4905_AT1 and 516_AT1 and 10476_AT2 and 515_AT1 and 522_AT1 and 521_AT1 and 10632_AT1) or (9551_AT3 and 4905_AT1 and 10476_AT1 and 518_AT2 and 521_AT1 and 522_AT4 and 515_AT2 and 10632_AT1) or (9551_AT3 and 516_AT2 and 4905_AT1 and 515_AT1 and 10476_AT1 and 522_AT1 and 521_AT1 and 10632_AT1) or (521_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1 and 4905_AT1 and 515_AT3 and 516_AT1 and 10476_AT1) or (522_AT5 and 4905_AT1 and 515_AT1 and 10476_AT2 and 521_AT1 and 518_AT1 and 9551_AT1 and 10632_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 522_AT4 and 521_AT1 and 517_AT2) or (4905_AT1 and 10476_AT2 and 518_AT3 and 521_AT1 and 515_AT2 and 522_AT1 and 9551_AT2 and 10632_AT1) or (521_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 516_AT2 and 522_AT2 and 10476_AT1 and 515_AT1) or (522_AT3 and 10632_AT1 and 9551_AT1 and 517_AT2 and 515_AT2 and 521_AT1 and 10476_AT2 and 4905_AT1) or (9551_AT3 and 4905_AT1 and 522_AT5 and 10476_AT2 and 515_AT1 and 516_AT1 and 521_AT1 and 10632_AT1) or (522_AT3 and 10632_AT1 and 521_AT1 and 518_AT1 and 515_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT3) or (517_AT1 and 521_AT1 and 10632_AT1 and 9551_AT2 and 522_AT2 and 4905_AT1 and 10476_AT2 and 515_AT3) or (10476_AT1 and 515_AT3 and 516_AT2 and 522_AT5 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 521_AT1) or (10632_AT1 and 522_AT3 and 521_AT1 and 518_AT1 and 515_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT3) or (10476_AT1 and 515_AT3 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 518_AT1 and 522_AT1 and 521_AT1) or (10632_AT1 and 515_AT2 and 521_AT1 and 518_AT1 and 10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT3) or (4905_AT1 and 518_AT2 and 10476_AT2 and 515_AT1 and 521_AT1 and 522_AT4 and 10632_AT1 and 9551_AT2) or (521_AT1 and 517_AT1 and 522_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 515_AT3 and 10476_AT1) or (515_AT3 and 518_AT2 and 10476_AT1 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 522_AT3 and 521_AT1) or (522_AT5 and 4905_AT1 and 516_AT2 and 10476_AT2 and 515_AT1 and 521_AT1 and 9551_AT2 and 10632_AT1) or (521_AT1 and 518_AT1 and 522_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 515_AT1 and 10476_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2 and 518_AT3 and 10476_AT1 and 4905_AT1 and 522_AT5) or (10476_AT2 and 515_AT3 and 516_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 522_AT4 and 521_AT1) or (515_AT3 and 518_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 521_AT1 and 522_AT1) or (10476_AT2 and 515_AT1 and 522_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 518_AT1 and 521_AT1) or (521_AT1 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 522_AT5 and 516_AT2 and 10476_AT2 and 515_AT3) or (522_AT5 and 4905_AT1 and 9551_AT3 and 10476_AT2 and 515_AT2 and 521_AT1 and 517_AT1 and 10632_AT1) or (4905_AT1 and 522_AT2 and 518_AT2 and 10476_AT2 and 521_AT1 and 515_AT2 and 9551_AT2 and 10632_AT1) or (515_AT3 and 10476_AT2 and 522_AT5 and 4905_AT1 and 10632_AT1 and 9551_AT2 and 521_AT1 and 518_AT1) or (518_AT3 and 10476_AT2 and 515_AT3 and 522_AT2 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 521_AT1) or (4905_AT1 and 10476_AT1 and 515_AT1 and 522_AT1 and 517_AT2 and 521_AT1 and 10632_AT1 and 9551_AT1) or (9551_AT1 and 10632_AT1 and 522_AT4 and 515_AT2 and 521_AT1 and 10476_AT2 and 516_AT2 and 4905_AT1) or (9551_AT2 and 10632_AT1 and 521_AT1 and 522_AT1 and 515_AT3 and 518_AT2 and 10476_AT2 and 4905_AT1) or (10476_AT2 and 518_AT3 and 4905_AT1 and 522_AT5 and 9551_AT2 and 10632_AT1 and 515_AT2 and 521_AT1) or (518_AT1 and 521_AT1 and 522_AT3 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT2 and 515_AT3) or (10476_AT1 and 515_AT3 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 522_AT1 and 517_AT2 and 521_AT1) or (4905_AT1 and 10476_AT1 and 515_AT1 and 521_AT1 and 522_AT4 and 518_AT1 and 9551_AT2 and 10632_AT1) or (522_AT3 and 10632_AT1 and 521_AT1 and 517_AT1 and 515_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT3) or (515_AT3 and 10476_AT1 and 4905_AT1 and 516_AT2 and 9551_AT2 and 10632_AT1 and 521_AT1 and 522_AT1) or (4905_AT1 and 10476_AT2 and 515_AT2 and 521_AT1 and 517_AT1 and 522_AT1 and 10632_AT1 and 9551_AT2) or (10476_AT2 and 518_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 521_AT1 and 522_AT4 and 515_AT2) or (10632_AT1 and 9551_AT2 and 522_AT4 and 521_AT1 and 518_AT1 and 515_AT3 and 10476_AT2 and 4905_AT1) or (4905_AT1 and 522_AT2 and 9551_AT3 and 518_AT2 and 10476_AT1 and 515_AT1 and 521_AT1 and 10632_AT1) or (515_AT2 and 522_AT4 and 521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 518_AT3 and 10476_AT2) or (4905_AT1 and 10476_AT1 and 515_AT1 and 517_AT1 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1) or (4905_AT1 and 10476_AT2 and 515_AT1 and 518_AT1 and 521_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1) or (522_AT2 and 9551_AT3 and 4905_AT1 and 518_AT3 and 10476_AT1 and 515_AT2 and 521_AT1 and 10632_AT1) or (518_AT1 and 521_AT1 and 515_AT2 and 522_AT4 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 10476_AT2) or (522_AT2 and 4905_AT1 and 515_AT1 and 10476_AT2 and 518_AT3 and 521_AT1 and 10632_AT1 and 9551_AT1) or (4905_AT1 and 522_AT5 and 10476_AT1 and 516_AT1 and 515_AT3 and 521_AT1 and 9551_AT2 and 10632_AT1) or (515_AT2 and 521_AT1 and 517_AT1 and 522_AT1 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 10476_AT1) or (9551_AT3 and 4905_AT1 and 518_AT3 and 10476_AT2 and 515_AT3 and 522_AT1 and 521_AT1 and 10632_AT1) or (10632_AT1 and 521_AT1 and 517_AT1 and 515_AT3 and 10476_AT1 and 4905_AT1 and 522_AT5 and 9551_AT3) or (521_AT1 and 522_AT3 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 518_AT3 and 10476_AT1 and 515_AT3) or (521_AT1 and 515_AT2 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 522_AT5 and 516_AT2 and 10476_AT2) or (10476_AT1 and 515_AT1 and 518_AT3 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 522_AT4 and 521_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT1 and 10632_AT1 and 521_AT1 and 517_AT2) or (4905_AT1 and 10476_AT1 and 517_AT1 and 522_AT1 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT1) or (10476_AT2 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2 and 522_AT1 and 517_AT1) or (4905_AT1 and 515_AT3 and 10476_AT1 and 521_AT1 and 518_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 9551_AT3 and 518_AT2 and 515_AT1 and 10476_AT2 and 521_AT1 and 522_AT3 and 10632_AT1) or (4905_AT1 and 10476_AT2 and 515_AT3 and 517_AT1 and 521_AT1 and 522_AT4 and 10632_AT1 and 9551_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 522_AT5 and 9551_AT1 and 10632_AT1 and 521_AT1 and 517_AT2) or (9551_AT2 and 10632_AT1 and 517_AT1 and 522_AT4 and 521_AT1 and 515_AT1 and 10476_AT1 and 4905_AT1) or (10632_AT1 and 521_AT1 and 518_AT1 and 515_AT3 and 10476_AT2 and 4905_AT1 and 522_AT5 and 9551_AT3) or (10632_AT1 and 521_AT1 and 10476_AT2 and 515_AT1 and 516_AT2 and 4905_AT1 and 522_AT2 and 9551_AT3) or (10476_AT2 and 518_AT3 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 521_AT1 and 515_AT2 and 522_AT1) or (10476_AT2 and 522_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT2 and 517_AT2 and 521_AT1 and 515_AT2) or (515_AT1 and 10476_AT1 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 517_AT2 and 522_AT1 and 521_AT1) or (10476_AT2 and 515_AT1 and 516_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 522_AT4 and 521_AT1 and 515_AT3 and 518_AT2 and 10476_AT1 and 4905_AT1 and 9551_AT3) or (518_AT2 and 10476_AT2 and 515_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT2 and 522_AT3 and 521_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 522_AT1 and 515_AT1 and 10476_AT2 and 4905_AT1 and 516_AT2) or (521_AT1 and 10632_AT1 and 522_AT3 and 4905_AT1 and 516_AT2 and 9551_AT3 and 515_AT3 and 10476_AT1) or (518_AT3 and 10476_AT1 and 522_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 521_AT1 and 515_AT2) or (522_AT5 and 4905_AT1 and 10476_AT1 and 515_AT3 and 517_AT1 and 521_AT1 and 10632_AT1 and 9551_AT2) or (518_AT1 and 522_AT4 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT2) or (522_AT1 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1) or (516_AT2 and 4905_AT1 and 9551_AT3 and 515_AT1 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT3) or (10476_AT2 and 518_AT2 and 9551_AT3 and 4905_AT1 and 522_AT5 and 10632_AT1 and 515_AT2 and 521_AT1) or (10476_AT1 and 516_AT2 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 515_AT2 and 521_AT1 and 522_AT1) or (10632_AT1 and 517_AT1 and 522_AT4 and 515_AT2 and 521_AT1 and 10476_AT1 and 9551_AT3 and 4905_AT1) or (522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT3) or (10632_AT1 and 521_AT1 and 515_AT2 and 522_AT4 and 10476_AT1 and 516_AT1 and 9551_AT3 and 4905_AT1) or (9551_AT2 and 10632_AT1 and 515_AT2 and 521_AT1 and 518_AT2 and 10476_AT1 and 4905_AT1 and 522_AT5) or (10476_AT1 and 515_AT3 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 517_AT2 and 522_AT4 and 521_AT1) or (4905_AT1 and 518_AT2 and 10476_AT2 and 515_AT1 and 521_AT1 and 9551_AT1 and 10632_AT1 and 522_AT3) or (516_AT2 and 4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 522_AT1 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 522_AT5 and 9551_AT3 and 518_AT2 and 10476_AT1 and 515_AT2 and 521_AT1 and 10632_AT1) or (516_AT2 and 4905_AT1 and 10476_AT2 and 522_AT4 and 515_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 522_AT5 and 10476_AT2 and 515_AT1 and 521_AT1 and 517_AT2 and 9551_AT1 and 10632_AT1) or (515_AT3 and 516_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1 and 521_AT1) or (9551_AT1 and 522_AT3 and 10632_AT1 and 521_AT1 and 515_AT1 and 10476_AT1 and 518_AT3 and 4905_AT1) or (522_AT1 and 518_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT2 and 515_AT3) or (521_AT1 and 515_AT2 and 518_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT2) or (521_AT1 and 10632_AT1 and 9551_AT1 and 4905_AT1 and 522_AT5 and 10476_AT2 and 515_AT1 and 518_AT2) or (10632_AT1 and 9551_AT1 and 517_AT2 and 522_AT4 and 521_AT1 and 10476_AT1 and 515_AT1 and 4905_AT1) or (521_AT1 and 10632_AT1 and 522_AT3 and 9551_AT1 and 516_AT2 and 4905_AT1 and 10476_AT2 and 515_AT1) or (517_AT1 and 522_AT4 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 515_AT1 and 10476_AT1) or (521_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT2 and 515_AT1 and 518_AT3 and 10476_AT1) or (10632_AT1 and 9551_AT1 and 518_AT1 and 521_AT1 and 10476_AT1 and 515_AT1 and 522_AT2 and 4905_AT1) or (10632_AT1 and 9551_AT1 and 522_AT4 and 521_AT1 and 515_AT1 and 10476_AT2 and 516_AT2 and 4905_AT1) or (522_AT3 and 10632_AT1 and 517_AT2 and 521_AT1 and 10476_AT1 and 515_AT1 and 9551_AT3 and 4905_AT1) or (10476_AT1 and 515_AT3 and 4905_AT1 and 522_AT3 and 10632_AT1 and 9551_AT1 and 518_AT1 and 521_AT1) or (4905_AT1 and 522_AT5 and 515_AT3 and 10476_AT2 and 521_AT1 and 518_AT1 and 9551_AT1 and 10632_AT1) or (10476_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 518_AT1 and 515_AT2 and 522_AT4 and 521_AT1) or (517_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 522_AT5 and 515_AT1 and 10476_AT1) or (515_AT1 and 10476_AT2 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 518_AT1 and 522_AT1 and 521_AT1) or (9551_AT3 and 4905_AT1 and 10476_AT2 and 517_AT1 and 521_AT1 and 522_AT4 and 515_AT2 and 10632_AT1) or (10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT2 and 10632_AT1 and 515_AT2 and 521_AT1 and 517_AT2) or (518_AT1 and 521_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT2 and 515_AT3) or (522_AT3 and 10632_AT1 and 9551_AT1 and 517_AT1 and 521_AT1 and 10476_AT2 and 515_AT3 and 4905_AT1) or (522_AT4 and 521_AT1 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 515_AT3 and 518_AT3 and 10476_AT2) or (10476_AT1 and 515_AT3 and 518_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 521_AT1 and 522_AT4) or (521_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT2 and 515_AT3 and 10476_AT2 and 516_AT1) or (10632_AT1 and 517_AT1 and 522_AT4 and 521_AT1 and 10476_AT2 and 515_AT1 and 9551_AT3 and 4905_AT1) or (10632_AT1 and 522_AT4 and 521_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 516_AT2 and 4905_AT1) or (9551_AT2 and 10632_AT1 and 515_AT2 and 521_AT1 and 518_AT3 and 10476_AT1 and 522_AT2 and 4905_AT1) or (9551_AT1 and 10632_AT1 and 515_AT2 and 521_AT1 and 522_AT1 and 518_AT2 and 10476_AT1 and 4905_AT1) or (9551_AT1 and 10632_AT1 and 515_AT2 and 522_AT4 and 521_AT1 and 517_AT1 and 10476_AT2 and 4905_AT1) or (10476_AT2 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 522_AT4 and 515_AT2 and 521_AT1 and 517_AT2) or (4905_AT1 and 522_AT5 and 10476_AT2 and 515_AT1 and 521_AT1 and 517_AT2 and 9551_AT2 and 10632_AT1) or (518_AT2 and 515_AT1 and 10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT2 and 10632_AT1 and 521_AT1) or (10632_AT1 and 9551_AT2 and 515_AT2 and 521_AT1 and 516_AT1 and 10476_AT2 and 522_AT2 and 4905_AT1) or (521_AT1 and 522_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 518_AT2 and 10476_AT1 and 515_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT3 and 518_AT2 and 10476_AT1 and 4905_AT1 and 522_AT2) or (515_AT1 and 10476_AT1 and 522_AT2 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 518_AT1 and 521_AT1) or (4905_AT1 and 10476_AT2 and 518_AT2 and 515_AT3 and 521_AT1 and 522_AT4 and 9551_AT2 and 10632_AT1) or (516_AT2 and 4905_AT1 and 522_AT2 and 515_AT3 and 10476_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1) or (9551_AT2 and 10632_AT1 and 522_AT1 and 521_AT1 and 516_AT1 and 10476_AT1 and 515_AT1 and 4905_AT1) or (515_AT2 and 522_AT4 and 521_AT1 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 518_AT2 and 10476_AT2) or (4905_AT1 and 522_AT5 and 9551_AT3 and 10476_AT2 and 515_AT1 and 521_AT1 and 518_AT1 and 10632_AT1) or (4905_AT1 and 522_AT2 and 10476_AT2 and 518_AT3 and 515_AT2 and 521_AT1 and 9551_AT1 and 10632_AT1) or (522_AT1 and 521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 10476_AT2 and 518_AT3 and 515_AT1) or (4905_AT1 and 522_AT5 and 518_AT2 and 10476_AT1 and 515_AT1 and 521_AT1 and 9551_AT1 and 10632_AT1) or (518_AT1 and 522_AT1 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT1) or (4905_AT1 and 515_AT1 and 10476_AT1 and 516_AT1 and 521_AT1 and 522_AT4 and 10632_AT1 and 9551_AT1) or (9551_AT2 and 10632_AT1 and 521_AT1 and 522_AT1 and 518_AT2 and 515_AT3 and 10476_AT1 and 4905_AT1) or (4905_AT1 and 515_AT1 and 10476_AT1 and 521_AT1 and 517_AT2 and 9551_AT1 and 522_AT3 and 10632_AT1) or (10476_AT2 and 516_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 522_AT1 and 521_AT1 and 515_AT2) or (10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2 and 517_AT2) or (4905_AT1 and 516_AT2 and 9551_AT3 and 515_AT3 and 10476_AT2 and 521_AT1 and 522_AT4 and 10632_AT1) or (4905_AT1 and 522_AT5 and 516_AT1 and 515_AT1 and 10476_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1) or (10476_AT2 and 516_AT1 and 515_AT3 and 9551_AT3 and 522_AT2 and 4905_AT1 and 10632_AT1 and 521_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 522_AT4 and 518_AT1 and 10476_AT2 and 515_AT1 and 4905_AT1) or (521_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT5 and 516_AT2 and 10476_AT1 and 515_AT1) or (521_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT2 and 515_AT3 and 10476_AT2 and 518_AT3) or (4905_AT1 and 522_AT2 and 9551_AT3 and 516_AT1 and 10476_AT1 and 515_AT2 and 521_AT1 and 10632_AT1) or (515_AT3 and 516_AT1 and 10476_AT1 and 4905_AT1 and 522_AT2 and 10632_AT1 and 9551_AT2 and 521_AT1) or (516_AT1 and 10476_AT1 and 9551_AT3 and 522_AT5 and 4905_AT1 and 10632_AT1 and 515_AT2 and 521_AT1) or (10476_AT1 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 518_AT1 and 515_AT2 and 522_AT4 and 521_AT1) or (9551_AT3 and 4905_AT1 and 522_AT5 and 10476_AT1 and 518_AT3 and 521_AT1 and 515_AT2 and 10632_AT1) or (9551_AT2 and 10632_AT1 and 521_AT1 and 515_AT3 and 518_AT3 and 10476_AT2 and 522_AT5 and 4905_AT1) or (4905_AT1 and 515_AT3 and 10476_AT1 and 521_AT1 and 518_AT1 and 522_AT1 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 10476_AT1 and 517_AT2 and 515_AT2 and 521_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 10476_AT1 and 515_AT3 and 518_AT2 and 521_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1) or (517_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5 and 4905_AT1 and 10476_AT1 and 515_AT3) or (522_AT5 and 4905_AT1 and 10476_AT2 and 518_AT2 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT1) or (10632_AT1 and 9551_AT1 and 517_AT1 and 521_AT1 and 515_AT1 and 10476_AT2 and 4905_AT1 and 522_AT5) or (521_AT1 and 10632_AT1 and 9551_AT1 and 522_AT2 and 4905_AT1 and 515_AT1 and 10476_AT2 and 518_AT2) or (10476_AT1 and 515_AT1 and 4905_AT1 and 516_AT2 and 522_AT2 and 9551_AT2 and 10632_AT1 and 521_AT1) or (4905_AT1 and 10476_AT2 and 515_AT3 and 517_AT1 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1) or (516_AT2 and 522_AT5 and 4905_AT1 and 10476_AT2 and 515_AT3 and 521_AT1 and 10632_AT1 and 9551_AT1) or (518_AT3 and 10476_AT2 and 515_AT3 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 522_AT1 and 521_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT2 and 522_AT4 and 521_AT1 and 518_AT1) or (10476_AT1 and 518_AT3 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 522_AT1 and 515_AT2 and 521_AT1) or (4905_AT1 and 522_AT2 and 10476_AT2 and 521_AT1 and 515_AT2 and 517_AT1 and 9551_AT1 and 10632_AT1) or (10632_AT1 and 521_AT1 and 516_AT1 and 10476_AT1 and 515_AT1 and 4905_AT1 and 522_AT5 and 9551_AT3) or (10632_AT1 and 521_AT1 and 517_AT2 and 515_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT3 and 522_AT2) or (521_AT1 and 522_AT4 and 517_AT2 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 10476_AT2 and 515_AT1) or (10476_AT1 and 516_AT1 and 4905_AT1 and 522_AT2 and 9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2) or (10632_AT1 and 9551_AT1 and 521_AT1 and 515_AT2 and 10476_AT2 and 518_AT2 and 522_AT2 and 4905_AT1) or (521_AT1 and 10632_AT1 and 9551_AT1 and 522_AT2 and 4905_AT1 and 516_AT2 and 10476_AT2 and 515_AT3) or (516_AT1 and 10476_AT2 and 515_AT1 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 521_AT1 and 522_AT1) or (10632_AT1 and 521_AT1 and 517_AT1 and 522_AT1 and 10476_AT1 and 515_AT1 and 4905_AT1 and 9551_AT3) or (10476_AT1 and 522_AT2 and 4905_AT1 and 516_AT2 and 10632_AT1 and 9551_AT1 and 521_AT1 and 515_AT2) or (10632_AT1 and 521_AT1 and 522_AT1 and 517_AT2 and 515_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT3) or (516_AT2 and 4905_AT1 and 10476_AT1 and 515_AT1 and 521_AT1 and 522_AT1 and 9551_AT2 and 10632_AT1) or (10476_AT1 and 4905_AT1 and 522_AT5 and 9551_AT2 and 10632_AT1 and 517_AT1 and 515_AT2 and 521_AT1) or (10476_AT1 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2 and 522_AT4 and 517_AT1) or (521_AT1 and 522_AT3 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 518_AT3 and 10476_AT1 and 515_AT1) or (521_AT1 and 515_AT2 and 522_AT1 and 517_AT2 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 10476_AT1) or (4905_AT1 and 10476_AT2 and 516_AT1 and 515_AT3 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1) or (10476_AT1 and 518_AT2 and 522_AT2 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 515_AT2 and 521_AT1) or (10476_AT2 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 515_AT2 and 522_AT4 and 521_AT1 and 518_AT1) or (4905_AT1 and 9551_AT3 and 515_AT1 and 10476_AT1 and 521_AT1 and 522_AT4 and 518_AT1 and 10632_AT1) or (10476_AT2 and 515_AT3 and 4905_AT1 and 516_AT2 and 10632_AT1 and 9551_AT2 and 521_AT1 and 522_AT4) or (4905_AT1 and 516_AT1 and 515_AT1 and 10476_AT1 and 522_AT4 and 521_AT1 and 9551_AT2 and 10632_AT1) or (522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT2 and 515_AT3 and 518_AT2) or (10632_AT1 and 9551_AT2 and 521_AT1 and 518_AT2 and 515_AT3 and 10476_AT2 and 4905_AT1 and 522_AT2) or (4905_AT1 and 522_AT2 and 515_AT3 and 10476_AT1 and 521_AT1 and 517_AT2 and 9551_AT2 and 10632_AT1) or (515_AT3 and 10476_AT2 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 522_AT4 and 521_AT1 and 517_AT2) or (10476_AT2 and 518_AT3 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2 and 522_AT1) or (522_AT5 and 4905_AT1 and 9551_AT3 and 518_AT2 and 515_AT3 and 10476_AT1 and 521_AT1 and 10632_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 522_AT1 and 515_AT1 and 10476_AT1 and 518_AT3 and 4905_AT1) or (521_AT1 and 515_AT2 and 522_AT1 and 517_AT2 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 10476_AT1) or (9551_AT2 and 10632_AT1 and 517_AT2 and 521_AT1 and 10476_AT2 and 515_AT3 and 522_AT2 and 4905_AT1) or (515_AT3 and 518_AT2 and 10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT3 and 10632_AT1 and 521_AT1) or (515_AT3 and 10476_AT2 and 516_AT2 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 521_AT1 and 522_AT1) or (521_AT1 and 515_AT2 and 517_AT2 and 10632_AT1 and 522_AT5 and 4905_AT1 and 9551_AT3 and 10476_AT2) or (522_AT3 and 10632_AT1 and 9551_AT1 and 521_AT1 and 515_AT1 and 10476_AT2 and 516_AT1 and 4905_AT1) or (521_AT1 and 10632_AT1 and 4905_AT1 and 516_AT2 and 9551_AT3 and 522_AT2 and 10476_AT1 and 515_AT1) or (522_AT5 and 4905_AT1 and 10476_AT1 and 515_AT1 and 521_AT1 and 517_AT2 and 9551_AT1 and 10632_AT1) or (521_AT1 and 9551_AT2 and 10632_AT1 and 522_AT5 and 4905_AT1 and 516_AT1 and 10476_AT2 and 515_AT3) or (517_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1 and 522_AT2 and 4905_AT1 and 10476_AT1 and 515_AT1) or (515_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 521_AT1 and 517_AT1 and 522_AT1) or (10632_AT1 and 9551_AT1 and 521_AT1 and 515_AT2 and 10476_AT1 and 518_AT2 and 522_AT5 and 4905_AT1) or (521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 522_AT5 and 516_AT1 and 515_AT1 and 10476_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT3 and 10476_AT2 and 516_AT1 and 522_AT5 and 4905_AT1) or (516_AT1 and 10476_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 515_AT2 and 522_AT4 and 521_AT1) or (515_AT3 and 10476_AT1 and 516_AT1 and 522_AT5 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 521_AT1) or (521_AT1 and 522_AT4 and 515_AT2 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 516_AT2 and 10476_AT1) or (4905_AT1 and 522_AT5 and 515_AT3 and 10476_AT1 and 521_AT1 and 517_AT2 and 9551_AT2 and 10632_AT1) or (515_AT2 and 522_AT4 and 521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 518_AT3 and 10476_AT1) or (517_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 522_AT5 and 515_AT1 and 10476_AT2) or (515_AT3 and 516_AT1 and 10476_AT1 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 522_AT4 and 521_AT1) or (521_AT1 and 10632_AT1 and 9551_AT1 and 522_AT2 and 4905_AT1 and 515_AT1 and 10476_AT2 and 516_AT1) or (515_AT2 and 521_AT1 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 522_AT2 and 518_AT2 and 10476_AT2) or (521_AT1 and 10632_AT1 and 522_AT2 and 9551_AT3 and 4905_AT1 and 10476_AT1 and 518_AT3 and 515_AT1) or (515_AT3 and 518_AT2 and 10476_AT2 and 4905_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1 and 521_AT1) or (10476_AT2 and 515_AT3 and 522_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 517_AT2 and 521_AT1) or (515_AT3 and 518_AT3 and 10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT3 and 10632_AT1 and 521_AT1) or (521_AT1 and 515_AT2 and 522_AT1 and 517_AT2 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 10476_AT2) or (9551_AT3 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT1 and 521_AT1 and 522_AT3 and 10632_AT1) or (10632_AT1 and 9551_AT1 and 517_AT2 and 522_AT4 and 521_AT1 and 10476_AT2 and 515_AT1 and 4905_AT1) or (4905_AT1 and 10476_AT1 and 518_AT2 and 515_AT2 and 521_AT1 and 522_AT3 and 10632_AT1 and 9551_AT1) or (4905_AT1 and 9551_AT3 and 515_AT1 and 10476_AT1 and 521_AT1 and 517_AT1 and 522_AT3 and 10632_AT1) or (4905_AT1 and 10476_AT2 and 516_AT1 and 515_AT3 and 522_AT1 and 521_AT1 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 10476_AT2 and 515_AT2 and 521_AT1 and 518_AT1 and 9551_AT1 and 522_AT3 and 10632_AT1) or (10632_AT1 and 9551_AT1 and 522_AT1 and 521_AT1 and 515_AT1 and 10476_AT1 and 516_AT2 and 4905_AT1) or (522_AT3 and 9551_AT2 and 10632_AT1 and 517_AT1 and 515_AT2 and 521_AT1 and 10476_AT2 and 4905_AT1) or (10476_AT2 and 515_AT3 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 522_AT1 and 518_AT1 and 521_AT1) or (516_AT1 and 10476_AT2 and 515_AT3 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 522_AT1 and 521_AT1) or (4905_AT1 and 522_AT5 and 515_AT3 and 518_AT3 and 10476_AT1 and 521_AT1 and 9551_AT1 and 10632_AT1) or (515_AT1 and 10476_AT1 and 522_AT5 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 521_AT1 and 517_AT2) or (515_AT1 and 10476_AT1 and 518_AT2 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 522_AT4 and 521_AT1) or (9551_AT2 and 522_AT3 and 10632_AT1 and 521_AT1 and 515_AT1 and 10476_AT2 and 518_AT3 and 4905_AT1) or (515_AT1 and 10476_AT1 and 516_AT2 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 522_AT3 and 521_AT1) or (10476_AT2 and 515_AT1 and 516_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT2 and 521_AT1 and 522_AT4) or (9551_AT1 and 10632_AT1 and 521_AT1 and 522_AT4 and 518_AT2 and 10476_AT2 and 515_AT1 and 4905_AT1) or (515_AT1 and 10476_AT1 and 4905_AT1 and 522_AT5 and 9551_AT3 and 10632_AT1 and 521_AT1 and 518_AT1) or (10476_AT1 and 516_AT1 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 521_AT1 and 515_AT2 and 522_AT1) or (4905_AT1 and 522_AT2 and 515_AT1 and 10476_AT2 and 521_AT1 and 518_AT1 and 9551_AT2 and 10632_AT1) or (10476_AT2 and 515_AT1 and 4905_AT1 and 10632_AT1 and 522_AT3 and 9551_AT1 and 518_AT1 and 521_AT1) or (9551_AT2 and 522_AT3 and 10632_AT1 and 517_AT1 and 521_AT1 and 10476_AT1 and 515_AT3 and 4905_AT1) or (515_AT2 and 521_AT1 and 518_AT1 and 522_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 10476_AT2) or (521_AT1 and 522_AT1 and 518_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 515_AT1 and 10476_AT2) or (4905_AT1 and 10476_AT1 and 522_AT1 and 517_AT2 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT2) or (10476_AT2 and 515_AT1 and 9551_AT3 and 4905_AT1 and 516_AT2 and 10632_AT1 and 521_AT1 and 522_AT4) or (9551_AT2 and 10632_AT1 and 522_AT1 and 515_AT2 and 521_AT1 and 10476_AT2 and 516_AT2 and 4905_AT1) or (10476_AT1 and 522_AT5 and 4905_AT1 and 516_AT2 and 10632_AT1 and 9551_AT2 and 521_AT1 and 515_AT2) or (9551_AT3 and 522_AT5 and 4905_AT1 and 516_AT2 and 10476_AT1 and 515_AT3 and 521_AT1 and 10632_AT1) or (516_AT1 and 515_AT1 and 10476_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 522_AT4 and 521_AT1) or (522_AT4 and 521_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 518_AT2 and 515_AT3 and 10476_AT2) or (522_AT3 and 10632_AT1 and 9551_AT1 and 521_AT1 and 10476_AT1 and 515_AT1 and 516_AT1 and 4905_AT1) or (4905_AT1 and 10476_AT2 and 518_AT2 and 522_AT1 and 515_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 522_AT5 and 10476_AT2 and 515_AT1 and 518_AT1 and 521_AT1 and 10632_AT1 and 9551_AT2) or (9551_AT2 and 10632_AT1 and 521_AT1 and 518_AT2 and 10476_AT1 and 515_AT1 and 522_AT5 and 4905_AT1) or (518_AT3 and 10476_AT2 and 9551_AT3 and 522_AT5 and 4905_AT1 and 10632_AT1 and 515_AT2 and 521_AT1) or (4905_AT1 and 10476_AT1 and 515_AT1 and 518_AT1 and 522_AT1 and 521_AT1 and 9551_AT2 and 10632_AT1) or (522_AT4 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 518_AT3 and 10476_AT2) or (516_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1 and 515_AT2 and 521_AT1) or (515_AT3 and 10476_AT1 and 518_AT3 and 522_AT5 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 521_AT1) or (4905_AT1 and 522_AT2 and 9551_AT3 and 515_AT1 and 10476_AT1 and 521_AT1 and 518_AT1 and 10632_AT1) or (521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 522_AT5 and 10476_AT1 and 516_AT1 and 515_AT3) or (10476_AT1 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 517_AT2 and 515_AT2 and 522_AT4 and 521_AT1) or (515_AT3 and 516_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 522_AT3 and 521_AT1) or (9551_AT2 and 522_AT3 and 10632_AT1 and 521_AT1 and 517_AT1 and 10476_AT2 and 515_AT1 and 4905_AT1) or (517_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1 and 522_AT2 and 4905_AT1 and 515_AT1 and 10476_AT2) or (10632_AT1 and 521_AT1 and 10476_AT1 and 518_AT3 and 515_AT1 and 522_AT5 and 4905_AT1 and 9551_AT3) or (4905_AT1 and 522_AT5 and 515_AT1 and 10476_AT2 and 518_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1) or (522_AT4 and 515_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 10476_AT2 and 518_AT2) or (9551_AT1 and 10632_AT1 and 521_AT1 and 522_AT4 and 515_AT2 and 518_AT2 and 10476_AT1 and 4905_AT1) or (515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2 and 516_AT2 and 4905_AT1 and 522_AT2 and 10476_AT1) or (10476_AT2 and 518_AT3 and 515_AT1 and 4905_AT1 and 522_AT5 and 9551_AT2 and 10632_AT1 and 521_AT1) or (9551_AT2 and 10632_AT1 and 517_AT2 and 521_AT1 and 522_AT4 and 10476_AT2 and 515_AT3 and 4905_AT1) or (521_AT1 and 518_AT1 and 9551_AT1 and 10632_AT1 and 522_AT5 and 4905_AT1 and 515_AT3 and 10476_AT1)) and ((509_AT1 and 498_AT3 and 514_AT2 and 513_AT1 and 506_AT1) or (509_AT1 and 498_AT2 and 506_AT1 and 514_AT1 and 513_AT2) or (506_AT1 and 513_AT2 and 509_AT2 and 514_AT2 and 498_AT2) or (509_AT1 and 506_AT1 and 498_AT1 and 513_AT2 and 514_AT1) or (514_AT1 and 513_AT2 and 506_AT1 and 509_AT2 and 498_AT2) or (513_AT1 and 509_AT2 and 514_AT2 and 498_AT2 and 506_AT1) or (509_AT1 and 498_AT3 and 506_AT1 and 513_AT2 and 514_AT1) or (506_AT1 and 513_AT2 and 498_AT3 and 514_AT2 and 509_AT2) or (506_AT1 and 498_AT1 and 513_AT2 and 514_AT1 and 509_AT2) or (514_AT1 and 513_AT2 and 506_AT1 and 509_AT2 and 498_AT3) or (498_AT1 and 506_AT1 and 513_AT2 and 509_AT2 and 514_AT2) or (513_AT2 and 506_AT1 and 514_AT2 and 498_AT3 and 509_AT1) or (509_AT1 and 513_AT1 and 498_AT1 and 506_AT1 and 514_AT1) or (513_AT1 and 514_AT2 and 509_AT1 and 498_AT1 and 506_AT1) or (506_AT1 and 514_AT1 and 509_AT1 and 513_AT1 and 498_AT2) or (498_AT3 and 509_AT2 and 514_AT2 and 513_AT1 and 506_AT1) or (514_AT1 and 506_AT1 and 498_AT1 and 513_AT1 and 509_AT2) or (509_AT1 and 514_AT2 and 498_AT2 and 513_AT1 and 506_AT1) or (509_AT2 and 498_AT2 and 513_AT1 and 506_AT1 and 514_AT1) or (509_AT1 and 498_AT2 and 514_AT2 and 506_AT1 and 513_AT2) or (514_AT1 and 506_AT1 and 509_AT2 and 513_AT1 and 498_AT3) or (513_AT1 and 498_AT3 and 509_AT1 and 514_AT1 and 506_AT1) or (498_AT1 and 506_AT1 and 509_AT2 and 514_AT2 and 513_AT1) or (513_AT2 and 498_AT1 and 506_AT1 and 514_AT2 and 509_AT1))",
"subsystem":"Oxidative Phosphorylation",
"notes":{
"original_bigg_ids":[
"ATPS4m"
]
},
"annotation":{
"bigg.reaction":[
"ATPS4m"
],
"biocyc":[
"META:ATPSYN-RXN"
],
"ec-code":[
"3.6.3.14"
],
"metanetx.reaction":[
"MNXR96136"
],
"sbo":"SBO:0000185",
"seed.reaction":[
"rxn08173",
"rxn10042"
]
}
},
{
"id":"ATPasel",
"name":"V-type ATPase, H+ transporting, lysosomal",
"metabolites":{
"adp_c":1.0,
"atp_c":-1.0,
"h2o_c":-1.0,
"h_c":-3.0,
"h_l":4.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"((527_AT1 and 533_AT1 and 9114_AT1 and 535_AT1 and 8992_AT1) or (9114_AT1 and 533_AT1 and 8992_AT1 and 23545_AT1 and 527_AT1) or (527_AT1 and 533_AT1 and 9114_AT1 and 10312_AT2 and 8992_AT1) or (10312_AT2 and 8992_AT1 and 533_AT1 and 245972_AT1 and 527_AT1) or (245972_AT1 and 527_AT1 and 8992_AT1 and 23545_AT1 and 533_AT1) or (50617_AT3 and 527_AT1 and 245972_AT1 and 533_AT1 and 8992_AT1) or (8992_AT1 and 9114_AT1 and 533_AT1 and 50617_AT1 and 527_AT1) or (50617_AT3 and 527_AT1 and 8992_AT1 and 9114_AT1 and 533_AT1) or (50617_AT2 and 8992_AT1 and 9114_AT1 and 533_AT1 and 527_AT1) or (533_AT1 and 8992_AT1 and 245972_AT1 and 527_AT1 and 50617_AT1) or (527_AT1 and 245972_AT1 and 533_AT1 and 50617_AT2 and 8992_AT1) or (533_AT1 and 535_AT1 and 8992_AT1 and 527_AT1 and 245972_AT1) or (527_AT1 and 10312_AT1 and 8992_AT1 and 533_AT1 and 9114_AT1) or (533_AT1 and 8992_AT1 and 527_AT1 and 10312_AT1 and 245972_AT1)) and ((51606_AT2 and 90423_AT1 and 523_AT1 and 9296_AT1 and 526_AT1 and 127124_AT2 and 528_AT2 and 51382_AT1) or (51606_AT1 and 523_AT1 and 526_AT1 and 9296_AT1 and 529_AT1 and 534_AT2 and 528_AT2 and 51382_AT1) or (528_AT2 and 529_AT1 and 9296_AT1 and 51382_AT1 and 525_AT1 and 51606_AT3 and 523_AT1 and 9550_AT1) or (528_AT2 and 9296_AT1 and 526_AT1 and 51382_AT1 and 127124_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1) or (9550_AT1 and 245973_AT1 and 51606_AT3 and 523_AT1 and 525_AT1 and 51382_AT1 and 9296_AT1 and 529_AT1) or (9550_AT1 and 51606_AT1 and 523_AT1 and 525_AT1 and 51382_AT1 and 528_AT1 and 9296_AT1 and 529_AT1) or (51606_AT3 and 523_AT1 and 529_AT1 and 534_AT2 and 526_AT1 and 9296_AT1 and 528_AT1 and 51382_AT1) or (528_AT1 and 51382_AT1 and 529_AT1 and 526_AT1 and 9296_AT1 and 9550_AT1 and 523_AT1 and 51606_AT3) or (523_AT1 and 51606_AT2 and 529_AT1 and 534_AT2 and 9296_AT1 and 526_AT1 and 528_AT1 and 51382_AT1) or (523_AT1 and 51606_AT3 and 127124_AT1 and 90423_AT1 and 9296_AT1 and 51382_AT1 and 528_AT1 and 525_AT1) or (51382_AT1 and 534_AT2 and 529_AT1 and 526_AT1 and 9296_AT1 and 523_AT1 and 245973_AT1 and 51606_AT2) or (9296_AT1 and 529_AT1 and 534_AT2 and 525_AT1 and 51382_AT1 and 528_AT1 and 51606_AT2 and 523_AT1) or (90423_AT1 and 51606_AT1 and 245973_AT1 and 523_AT1 and 51382_AT1 and 526_AT1 and 9296_AT1 and 534_AT2) or (127124_AT1 and 523_AT1 and 51606_AT3 and 51382_AT1 and 9296_AT1 and 526_AT1 and 528_AT2 and 529_AT1) or (523_AT1 and 51606_AT1 and 245973_AT1 and 90423_AT1 and 127124_AT2 and 526_AT1 and 9296_AT1 and 51382_AT1) or (9550_AT1 and 523_AT1 and 51606_AT1 and 245973_AT1 and 51382_AT1 and 525_AT1 and 529_AT1 and 9296_AT1) or (525_AT1 and 51382_AT1 and 528_AT1 and 9296_AT1 and 534_AT2 and 51606_AT1 and 90423_AT1 and 523_AT1) or (51382_AT1 and 529_AT1 and 528_AT2 and 526_AT1 and 127124_AT2 and 9296_AT1 and 51606_AT3 and 523_AT1) or (90423_AT1 and 127124_AT1 and 523_AT1 and 51606_AT3 and 9296_AT1 and 526_AT1 and 51382_AT1 and 528_AT1) or (51382_AT1 and 127124_AT2 and 526_AT1 and 9296_AT1 and 528_AT2 and 90423_AT1 and 523_AT1 and 51606_AT3) or (90423_AT1 and 51606_AT1 and 523_AT1 and 526_AT1 and 9296_AT1 and 534_AT2 and 528_AT2 and 51382_AT1) or (245973_AT1 and 127124_AT1 and 523_AT1 and 51606_AT3 and 51382_AT1 and 9296_AT1 and 526_AT1 and 529_AT1) or (526_AT1 and 9296_AT1 and 51382_AT1 and 90423_AT1 and 245973_AT1 and 523_AT1 and 51606_AT3 and 127124_AT1) or (9296_AT1 and 534_AT2 and 525_AT1 and 51382_AT1 and 90423_AT1 and 245973_AT1 and 51606_AT3 and 523_AT1) or (525_AT1 and 51382_AT1 and 9296_AT1 and 528_AT2 and 51606_AT1 and 534_AT1 and 90423_AT1 and 523_AT1) or (525_AT1 and 528_AT1 and 51382_AT1 and 127124_AT2 and 9296_AT1 and 529_AT1 and 523_AT1 and 51606_AT3) or (51382_AT1 and 526_AT1 and 9296_AT1 and 529_AT1 and 534_AT1 and 245973_AT1 and 51606_AT2 and 523_AT1) or (529_AT1 and 528_AT2 and 526_AT1 and 9296_AT1 and 51382_AT1 and 523_AT1 and 51606_AT1 and 9550_AT1) or (523_AT1 and 51606_AT1 and 90423_AT1 and 9550_AT1 and 9296_AT1 and 528_AT1 and 51382_AT1 and 525_AT1) or (523_AT1 and 245973_AT1 and 51606_AT1 and 51382_AT1 and 529_AT1 and 127124_AT2 and 526_AT1 and 9296_AT1) or (90423_AT1 and 51606_AT1 and 523_AT1 and 9296_AT1 and 526_AT1 and 127124_AT2 and 528_AT2 and 51382_AT1) or (51382_AT1 and 528_AT1 and 526_AT1 and 9296_AT1 and 529_AT1 and 534_AT1 and 523_AT1 and 51606_AT3) or (523_AT1 and 51606_AT2 and 90423_AT1 and 534_AT2 and 9296_AT1 and 528_AT1 and 51382_AT1 and 525_AT1) or (245973_AT1 and 51606_AT2 and 523_AT1 and 9296_AT1 and 529_AT1 and 534_AT2 and 525_AT1 and 51382_AT1) or (523_AT1 and 51606_AT2 and 90423_AT1 and 528_AT2 and 9296_AT1 and 127124_AT2 and 51382_AT1 and 525_AT1) or (523_AT1 and 51606_AT1 and 245973_AT1 and 534_AT1 and 529_AT1 and 9296_AT1 and 51382_AT1 and 525_AT1) or (523_AT1 and 51606_AT2 and 534_AT1 and 90423_AT1 and 9296_AT1 and 51382_AT1 and 528_AT1 and 525_AT1) or (528_AT2 and 526_AT1 and 9296_AT1 and 51382_AT1 and 51606_AT3 and 523_AT1 and 534_AT1 and 90423_AT1) or (523_AT1 and 51606_AT3 and 245973_AT1 and 534_AT1 and 529_AT1 and 9296_AT1 and 526_AT1 and 51382_AT1) or (245973_AT1 and 51606_AT1 and 90423_AT1 and 523_AT1 and 127124_AT1 and 525_AT1 and 51382_AT1 and 9296_AT1) or (523_AT1 and 90423_AT1 and 51606_AT1 and 9296_AT1 and 127124_AT2 and 528_AT1 and 51382_AT1 and 525_AT1) or (523_AT1 and 127124_AT1 and 245973_AT1 and 90423_AT1 and 51606_AT2 and 51382_AT1 and 525_AT1 and 9296_AT1) or (534_AT2 and 9296_AT1 and 526_AT1 and 51382_AT1 and 523_AT1 and 51606_AT2 and 245973_AT1 and 90423_AT1) or (51382_AT1 and 528_AT1 and 526_AT1 and 9296_AT1 and 534_AT1 and 90423_AT1 and 51606_AT3 and 523_AT1) or (528_AT2 and 9296_AT1 and 526_AT1 and 51382_AT1 and 523_AT1 and 534_AT1 and 51606_AT1 and 90423_AT1) or (523_AT1 and 245973_AT1 and 90423_AT1 and 51606_AT2 and 51382_AT1 and 127124_AT2 and 526_AT1 and 9296_AT1) or (90423_AT1 and 51606_AT3 and 523_AT1 and 9550_AT1 and 526_AT1 and 9296_AT1 and 51382_AT1 and 528_AT1) or (529_AT1 and 9296_AT1 and 526_AT1 and 127124_AT2 and 51382_AT1 and 523_AT1 and 51606_AT3 and 245973_AT1) or (529_AT1 and 528_AT2 and 9296_AT1 and 51382_AT1 and 525_AT1 and 51606_AT3 and 523_AT1 and 534_AT1) or (127124_AT1 and 523_AT1 and 51606_AT1 and 529_AT1 and 9296_AT1 and 528_AT1 and 51382_AT1 and 525_AT1) or (523_AT1 and 51606_AT3 and 9550_AT1 and 528_AT2 and 529_AT1 and 9296_AT1 and 526_AT1 and 51382_AT1) or (51382_AT1 and 528_AT1 and 526_AT1 and 9296_AT1 and 534_AT2 and 90423_AT1 and 51606_AT3 and 523_AT1) or (529_AT1 and 528_AT2 and 526_AT1 and 9296_AT1 and 51382_AT1 and 523_AT1 and 534_AT1 and 51606_AT2) or (529_AT1 and 9296_AT1 and 526_AT1 and 528_AT1 and 51382_AT1 and 523_AT1 and 51606_AT2 and 9550_AT1) or (9296_AT1 and 526_AT1 and 127124_AT2 and 529_AT1 and 51382_AT1 and 528_AT1 and 51606_AT2 and 523_AT1) or (523_AT1 and 51606_AT1 and 51382_AT1 and 528_AT1 and 529_AT1 and 127124_AT2 and 526_AT1 and 9296_AT1) or (523_AT1 and 51606_AT3 and 525_AT1 and 51382_AT1 and 9296_AT1 and 534_AT2 and 529_AT1 and 528_AT2) or (523_AT1 and 245973_AT1 and 51606_AT2 and 51382_AT1 and 529_AT1 and 526_AT1 and 127124_AT2 and 9296_AT1) or (9296_AT1 and 528_AT2 and 525_AT1 and 51382_AT1 and 51606_AT1 and 90423_AT1 and 523_AT1 and 9550_AT1) or (528_AT2 and 534_AT2 and 9296_AT1 and 526_AT1 and 51382_AT1 and 51606_AT3 and 523_AT1 and 90423_AT1) or (51382_AT1 and 528_AT2 and 526_AT1 and 9296_AT1 and 9550_AT1 and 523_AT1 and 51606_AT3 and 90423_AT1) or (90423_AT1 and 127124_AT1 and 51606_AT3 and 523_AT1 and 9296_AT1 and 528_AT2 and 525_AT1 and 51382_AT1) or (534_AT1 and 90423_AT1 and 245973_AT1 and 51606_AT1 and 523_AT1 and 525_AT1 and 51382_AT1 and 9296_AT1) or (9296_AT1 and 534_AT2 and 529_AT1 and 528_AT2 and 525_AT1 and 51382_AT1 and 51606_AT2 and 523_AT1) or (127124_AT1 and 523_AT1 and 51606_AT3 and 529_AT1 and 9296_AT1 and 528_AT1 and 51382_AT1 and 525_AT1) or (528_AT1 and 51382_AT1 and 526_AT1 and 9296_AT1 and 90423_AT1 and 534_AT1 and 51606_AT2 and 523_AT1) or (51382_AT1 and 528_AT1 and 9296_AT1 and 526_AT1 and 51606_AT2 and 90423_AT1 and 127124_AT1 and 523_AT1) or (9296_AT1 and 526_AT1 and 528_AT2 and 529_AT1 and 51382_AT1 and 534_AT1 and 51606_AT1 and 523_AT1) or (9296_AT1 and 528_AT1 and 51382_AT1 and 525_AT1 and 523_AT1 and 127124_AT1 and 51606_AT1 and 90423_AT1) or (51606_AT1 and 245973_AT1 and 523_AT1 and 525_AT1 and 51382_AT1 and 9296_AT1 and 127124_AT2 and 529_AT1) or (526_AT1 and 9296_AT1 and 529_AT1 and 51382_AT1 and 245973_AT1 and 51606_AT3 and 523_AT1 and 9550_AT1) or (51382_AT1 and 9296_AT1 and 526_AT1 and 529_AT1 and 9550_AT1 and 51606_AT2 and 245973_AT1 and 523_AT1) or (51382_AT1 and 525_AT1 and 528_AT2 and 529_AT1 and 9296_AT1 and 127124_AT1 and 51606_AT3 and 523_AT1) or (51382_AT1 and 528_AT1 and 525_AT1 and 127124_AT2 and 9296_AT1 and 523_AT1 and 51606_AT3 and 90423_AT1) or (523_AT1 and 245973_AT1 and 51606_AT1 and 9550_AT1 and 529_AT1 and 9296_AT1 and 526_AT1 and 51382_AT1) or (9296_AT1 and 525_AT1 and 528_AT1 and 51382_AT1 and 90423_AT1 and 51606_AT2 and 523_AT1 and 9550_AT1) or (525_AT1 and 51382_AT1 and 9296_AT1 and 528_AT2 and 534_AT2 and 90423_AT1 and 523_AT1 and 51606_AT3) or (51382_AT1 and 526_AT1 and 9296_AT1 and 528_AT2 and 90423_AT1 and 51606_AT3 and 523_AT1 and 127124_AT1) or (523_AT1 and 127124_AT1 and 51606_AT2 and 51382_AT1 and 529_AT1 and 528_AT2 and 526_AT1 and 9296_AT1) or (523_AT1 and 51606_AT1 and 245973_AT1 and 534_AT2 and 529_AT1 and 9296_AT1 and 51382_AT1 and 525_AT1) or (51382_AT1 and 525_AT1 and 9296_AT1 and 127124_AT2 and 523_AT1 and 51606_AT1 and 245973_AT1 and 90423_AT1) or (9550_AT1 and 51606_AT1 and 523_AT1 and 51382_AT1 and 528_AT1 and 9296_AT1 and 526_AT1 and 529_AT1) or (9550_AT1 and 51606_AT2 and 523_AT1 and 525_AT1 and 51382_AT1 and 9296_AT1 and 529_AT1 and 528_AT2) or (51382_AT1 and 528_AT2 and 9296_AT1 and 526_AT1 and 127124_AT1 and 523_AT1 and 51606_AT2 and 90423_AT1) or (127124_AT2 and 9296_AT1 and 529_AT1 and 528_AT2 and 525_AT1 and 51382_AT1 and 51606_AT1 and 523_AT1) or (51606_AT1 and 523_AT1 and 9296_AT1 and 526_AT1 and 534_AT2 and 529_AT1 and 528_AT1 and 51382_AT1) or (529_AT1 and 9296_AT1 and 51382_AT1 and 525_AT1 and 127124_AT1 and 523_AT1 and 245973_AT1 and 51606_AT1) or (528_AT1 and 51382_AT1 and 525_AT1 and 9296_AT1 and 523_AT1 and 90423_AT1 and 534_AT1 and 51606_AT1) or (529_AT1 and 9296_AT1 and 51382_AT1 and 525_AT1 and 523_AT1 and 51606_AT2 and 534_AT1 and 245973_AT1) or (245973_AT1 and 51606_AT2 and 523_AT1 and 127124_AT1 and 9296_AT1 and 529_AT1 and 525_AT1 and 51382_AT1) or (9296_AT1 and 529_AT1 and 525_AT1 and 528_AT1 and 51382_AT1 and 51606_AT1 and 534_AT1 and 523_AT1) or (90423_AT1 and 523_AT1 and 51606_AT3 and 525_AT1 and 51382_AT1 and 127124_AT2 and 9296_AT1 and 528_AT2) or (9296_AT1 and 529_AT1 and 525_AT1 and 51382_AT1 and 528_AT1 and 51606_AT3 and 523_AT1 and 9550_AT1) or (525_AT1 and 51382_AT1 and 9296_AT1 and 528_AT2 and 529_AT1 and 51606_AT1 and 127124_AT1 and 523_AT1) or (529_AT1 and 526_AT1 and 9296_AT1 and 51382_AT1 and 528_AT1 and 523_AT1 and 534_AT1 and 51606_AT2) or (523_AT1 and 51606_AT1 and 534_AT1 and 528_AT1 and 51382_AT1 and 529_AT1 and 526_AT1 and 9296_AT1) or (528_AT2 and 526_AT1 and 9296_AT1 and 51382_AT1 and 523_AT1 and 51606_AT1 and 90423_AT1 and 9550_AT1) or (51606_AT1 and 523_AT1 and 51382_AT1 and 9296_AT1 and 127124_AT2 and 526_AT1 and 528_AT2 and 529_AT1) or (51382_AT1 and 529_AT1 and 9296_AT1 and 526_AT1 and 523_AT1 and 534_AT1 and 51606_AT1 and 245973_AT1) or (51606_AT1 and 523_AT1 and 127124_AT1 and 51382_AT1 and 526_AT1 and 9296_AT1 and 529_AT1 and 528_AT2) or (523_AT1 and 51606_AT3 and 245973_AT1 and 90423_AT1 and 9296_AT1 and 526_AT1 and 127124_AT2 and 51382_AT1) or (51606_AT3 and 523_AT1 and 245973_AT1 and 534_AT2 and 529_AT1 and 9296_AT1 and 51382_AT1 and 525_AT1) or (9550_AT1 and 90423_AT1 and 51606_AT2 and 523_AT1 and 525_AT1 and 51382_AT1 and 9296_AT1 and 528_AT2) or (51606_AT3 and 523_AT1 and 127124_AT1 and 90423_AT1 and 245973_AT1 and 9296_AT1 and 51382_AT1 and 525_AT1) or (525_AT1 and 51382_AT1 and 9296_AT1 and 534_AT2 and 245973_AT1 and 51606_AT1 and 90423_AT1 and 523_AT1) or (51606_AT2 and 523_AT1 and 127124_AT1 and 525_AT1 and 528_AT1 and 51382_AT1 and 9296_AT1 and 529_AT1) or (51606_AT2 and 245973_AT1 and 523_AT1 and 9296_AT1 and 127124_AT2 and 529_AT1 and 525_AT1 and 51382_AT1) or (51382_AT1 and 9296_AT1 and 526_AT1 and 90423_AT1 and 51606_AT1 and 245973_AT1 and 127124_AT1 and 523_AT1) or (529_AT1 and 9296_AT1 and 127124_AT2 and 528_AT1 and 51382_AT1 and 525_AT1 and 523_AT1 and 51606_AT1) or (51382_AT1 and 529_AT1 and 528_AT2 and 526_AT1 and 9296_AT1 and 523_AT1 and 51606_AT3 and 534_AT1) or (523_AT1 and 90423_AT1 and 51606_AT1 and 534_AT2 and 528_AT2 and 9296_AT1 and 51382_AT1 and 525_AT1) or (127124_AT2 and 9296_AT1 and 528_AT2 and 525_AT1 and 51382_AT1 and 51606_AT1 and 90423_AT1 and 523_AT1) or (523_AT1 and 51606_AT2 and 9550_AT1 and 529_AT1 and 528_AT2 and 526_AT1 and 9296_AT1 and 51382_AT1) or (90423_AT1 and 245973_AT1 and 523_AT1 and 51606_AT3 and 127124_AT2 and 9296_AT1 and 525_AT1 and 51382_AT1) or (523_AT1 and 51606_AT3 and 245973_AT1 and 51382_AT1 and 534_AT2 and 529_AT1 and 9296_AT1 and 526_AT1) or (523_AT1 and 534_AT1 and 90423_AT1 and 245973_AT1 and 51606_AT2 and 51382_AT1 and 526_AT1 and 9296_AT1) or (523_AT1 and 51606_AT2 and 534_AT1 and 529_AT1 and 9296_AT1 and 51382_AT1 and 528_AT1 and 525_AT1) or (523_AT1 and 127124_AT1 and 245973_AT1 and 51606_AT1 and 529_AT1 and 526_AT1 and 9296_AT1 and 51382_AT1) or (534_AT2 and 526_AT1 and 9296_AT1 and 528_AT1 and 51382_AT1 and 523_AT1 and 90423_AT1 and 51606_AT2) or (9550_AT1 and 523_AT1 and 51606_AT1 and 51382_AT1 and 525_AT1 and 529_AT1 and 528_AT2 and 9296_AT1) or (9296_AT1 and 528_AT2 and 529_AT1 and 534_AT2 and 525_AT1 and 51382_AT1 and 51606_AT1 and 523_AT1) or (523_AT1 and 127124_AT1 and 90423_AT1 and 51606_AT1 and 526_AT1 and 9296_AT1 and 51382_AT1 and 528_AT1) or (526_AT1 and 9296_AT1 and 528_AT1 and 51382_AT1 and 90423_AT1 and 51606_AT1 and 523_AT1 and 9550_AT1) or (523_AT1 and 534_AT1 and 51606_AT2 and 529_AT1 and 528_AT2 and 9296_AT1 and 51382_AT1 and 525_AT1) or (9550_AT1 and 523_AT1 and 51606_AT2 and 245973_AT1 and 90423_AT1 and 51382_AT1 and 9296_AT1 and 526_AT1) or (528_AT1 and 51382_AT1 and 525_AT1 and 9296_AT1 and 127124_AT2 and 523_AT1 and 51606_AT2 and 90423_AT1) or (525_AT1 and 51382_AT1 and 9296_AT1 and 529_AT1 and 245973_AT1 and 127124_AT1 and 51606_AT3 and 523_AT1) or (127124_AT1 and 523_AT1 and 51606_AT2 and 90423_AT1 and 528_AT1 and 51382_AT1 and 525_AT1 and 9296_AT1) or (51382_AT1 and 528_AT1 and 127124_AT2 and 526_AT1 and 9296_AT1 and 90423_AT1 and 51606_AT2 and 523_AT1) or (127124_AT2 and 526_AT1 and 9296_AT1 and 51382_AT1 and 528_AT1 and 523_AT1 and 51606_AT1 and 90423_AT1) or (51382_AT1 and 525_AT1 and 529_AT1 and 528_AT2 and 9296_AT1 and 523_AT1 and 127124_AT1 and 51606_AT2) or (529_AT1 and 9296_AT1 and 51382_AT1 and 525_AT1 and 51606_AT3 and 523_AT1 and 245973_AT1 and 534_AT1) or (51606_AT3 and 523_AT1 and 51382_AT1 and 9296_AT1 and 526_AT1 and 528_AT2 and 534_AT2 and 529_AT1) or (9296_AT1 and 526_AT1 and 51382_AT1 and 127124_AT1 and 523_AT1 and 51606_AT2 and 90423_AT1 and 245973_AT1) or (523_AT1 and 51606_AT2 and 90423_AT1 and 9550_AT1 and 9296_AT1 and 526_AT1 and 51382_AT1 and 528_AT1) or (9296_AT1 and 526_AT1 and 528_AT2 and 534_AT2 and 51382_AT1 and 51606_AT2 and 90423_AT1 and 523_AT1) or (9550_AT1 and 523_AT1 and 51606_AT3 and 245973_AT1 and 90423_AT1 and 51382_AT1 and 9296_AT1 and 526_AT1) or (9296_AT1 and 525_AT1 and 51382_AT1 and 245973_AT1 and 90423_AT1 and 51606_AT2 and 523_AT1 and 9550_AT1) or (534_AT2 and 9296_AT1 and 51382_AT1 and 525_AT1 and 523_AT1 and 51606_AT2 and 90423_AT1 and 245973_AT1) or (534_AT2 and 529_AT1 and 526_AT1 and 9296_AT1 and 51382_AT1 and 523_AT1 and 245973_AT1 and 51606_AT1) or (525_AT1 and 51382_AT1 and 9296_AT1 and 9550_AT1 and 90423_AT1 and 245973_AT1 and 523_AT1 and 51606_AT3) or (51606_AT2 and 90423_AT1 and 127124_AT1 and 523_AT1 and 525_AT1 and 51382_AT1 and 9296_AT1 and 528_AT2) or (9550_AT1 and 245973_AT1 and 51606_AT2 and 523_AT1 and 525_AT1 and 51382_AT1 and 9296_AT1 and 529_AT1) or (523_AT1 and 245973_AT1 and 90423_AT1 and 534_AT1 and 51606_AT2 and 51382_AT1 and 525_AT1 and 9296_AT1) or (9296_AT1 and 528_AT2 and 525_AT1 and 51382_AT1 and 90423_AT1 and 523_AT1 and 51606_AT3 and 9550_AT1) or (51606_AT2 and 523_AT1 and 526_AT1 and 127124_AT2 and 9296_AT1 and 529_AT1 and 528_AT2 and 51382_AT1) or (526_AT1 and 9296_AT1 and 51382_AT1 and 245973_AT1 and 534_AT1 and 90423_AT1 and 523_AT1 and 51606_AT3) or (51382_AT1 and 525_AT1 and 528_AT2 and 9296_AT1 and 51606_AT3 and 523_AT1 and 90423_AT1 and 534_AT1) or (9296_AT1 and 51382_AT1 and 525_AT1 and 523_AT1 and 245973_AT1 and 51606_AT1 and 90423_AT1 and 9550_AT1) or (523_AT1 and 534_AT1 and 90423_AT1 and 51606_AT2 and 51382_AT1 and 525_AT1 and 528_AT2 and 9296_AT1) or (51382_AT1 and 528_AT1 and 127124_AT2 and 526_AT1 and 9296_AT1 and 90423_AT1 and 523_AT1 and 51606_AT3) or (523_AT1 and 51606_AT2 and 534_AT1 and 90423_AT1 and 528_AT2 and 9296_AT1 and 526_AT1 and 51382_AT1) or (529_AT1 and 9296_AT1 and 526_AT1 and 51382_AT1 and 528_AT1 and 127124_AT1 and 523_AT1 and 51606_AT1) or (51606_AT2 and 127124_AT1 and 523_AT1 and 51382_AT1 and 528_AT1 and 9296_AT1 and 526_AT1 and 529_AT1) or (525_AT1 and 528_AT1 and 51382_AT1 and 9296_AT1 and 127124_AT2 and 529_AT1 and 51606_AT2 and 523_AT1) or (90423_AT1 and 245973_AT1 and 51606_AT3 and 523_AT1 and 51382_AT1 and 526_AT1 and 9296_AT1 and 534_AT2) or (51382_AT1 and 528_AT1 and 9296_AT1 and 526_AT1 and 523_AT1 and 51606_AT1 and 534_AT1 and 90423_AT1) or (51382_AT1 and 528_AT1 and 525_AT1 and 9296_AT1 and 9550_AT1 and 523_AT1 and 51606_AT3 and 90423_AT1) or (523_AT1 and 51606_AT1 and 534_AT1 and 528_AT2 and 529_AT1 and 9296_AT1 and 51382_AT1 and 525_AT1) or (528_AT1 and 51382_AT1 and 526_AT1 and 127124_AT2 and 9296_AT1 and 529_AT1 and 523_AT1 and 51606_AT3) or (90423_AT1 and 51606_AT1 and 523_AT1 and 528_AT1 and 51382_AT1 and 526_AT1 and 9296_AT1 and 534_AT2) or (51382_AT1 and 528_AT2 and 526_AT1 and 9296_AT1 and 9550_AT1 and 523_AT1 and 90423_AT1 and 51606_AT2) or (127124_AT1 and 523_AT1 and 51606_AT2 and 245973_AT1 and 51382_AT1 and 529_AT1 and 9296_AT1 and 526_AT1) or (525_AT1 and 51382_AT1 and 9296_AT1 and 528_AT2 and 534_AT2 and 51606_AT2 and 90423_AT1 and 523_AT1) or (51606_AT3 and 523_AT1 and 525_AT1 and 51382_AT1 and 127124_AT2 and 9296_AT1 and 529_AT1 and 528_AT2) or (51382_AT1 and 525_AT1 and 9296_AT1 and 523_AT1 and 51606_AT3 and 90423_AT1 and 245973_AT1 and 534_AT1) or (9296_AT1 and 526_AT1 and 51382_AT1 and 523_AT1 and 534_AT1 and 51606_AT1 and 90423_AT1 and 245973_AT1) or (51606_AT1 and 523_AT1 and 525_AT1 and 528_AT1 and 51382_AT1 and 9296_AT1 and 529_AT1 and 534_AT2) or (127124_AT2 and 9296_AT1 and 51382_AT1 and 525_AT1 and 523_AT1 and 245973_AT1 and 90423_AT1 and 51606_AT2) or (51606_AT3 and 523_AT1 and 534_AT1 and 90423_AT1 and 51382_AT1 and 528_AT1 and 525_AT1 and 9296_AT1) or (51606_AT2 and 523_AT1 and 9550_AT1 and 9296_AT1 and 529_AT1 and 525_AT1 and 51382_AT1 and 528_AT1) or (90423_AT1 and 51606_AT3 and 523_AT1 and 525_AT1 and 51382_AT1 and 528_AT1 and 9296_AT1 and 534_AT2) or (523_AT1 and 51606_AT3 and 245973_AT1 and 51382_AT1 and 525_AT1 and 529_AT1 and 9296_AT1 and 127124_AT2) or (51382_AT1 and 525_AT1 and 528_AT2 and 529_AT1 and 9296_AT1 and 127124_AT2 and 523_AT1 and 51606_AT2) or (90423_AT1 and 51606_AT1 and 127124_AT1 and 523_AT1 and 525_AT1 and 51382_AT1 and 9296_AT1 and 528_AT2) or (526_AT1 and 9296_AT1 and 51382_AT1 and 523_AT1 and 245973_AT1 and 51606_AT1 and 90423_AT1 and 9550_AT1) or (523_AT1 and 51606_AT3 and 534_AT1 and 529_AT1 and 9296_AT1 and 51382_AT1 and 528_AT1 and 525_AT1) or (525_AT1 and 51382_AT1 and 528_AT1 and 9296_AT1 and 534_AT2 and 529_AT1 and 51606_AT3 and 523_AT1) or (51606_AT2 and 523_AT1 and 51382_AT1 and 9296_AT1 and 526_AT1 and 528_AT2 and 529_AT1 and 534_AT2) or (9296_AT1 and 526_AT1 and 529_AT1 and 528_AT1 and 51382_AT1 and 127124_AT1 and 523_AT1 and 51606_AT3))",
"subsystem":"Transport, Lysosomal",
"notes":{
"original_bigg_ids":[
"ATPasel"
]
},
"annotation":{
"bigg.reaction":[
"ATPasel"
],
"biocyc":[
"META:ATPSYN-RXN"
],
"ec-code":[
"3.6.3.14"
],
"metanetx.reaction":[
"MNXR96136"
],
"sbo":"SBO:0000185",
"seed.reaction":[
"rxn08173",
"rxn10042"
]
}
},
{
"id":"ATPtm",
"name":"ADP/ATP transporter, mitochondrial",
"metabolites":{
"adp_c":-1.0,
"adp_m":1.0,
"atp_c":1.0,
"atp_m":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"293_AT1 or 292_AT1 or 291_AT1",
"subsystem":"Transport, Mitochondrial",
"notes":{
"original_bigg_ids":[
"ATPtm"
]
},
"annotation":{
"bigg.reaction":[
"ATPtm"
],
"ec-code":[
"2.7.4.6"
],
"kegg.reaction":[
"R00124#2"
],
"metanetx.reaction":[
"MNXR96123"
],
"reactome.reaction":[
"R-TGU-163215",
"R-CEL-163215",
"R-ATH-163215",
"R-BTA-5672027",
"R-BTA-163215",
"R-RNO-163215",
"R-MMU-5672027",
"R-GGA-163215",
"R-DRE-5672027",
"R-HSA-5672027",
"R-RNO-5672027",
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"R-DDI-163215",
"R-SSC-163215",
"R-SCE-163215",
"R-XTR-163215",
"R-XTR-5672027",
"R-SSC-5672027",
"R-DME-163215"
],
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"35000",
"35002",
"35001"
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}
},
{
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}
},
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}
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}
},
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}
},
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}
},
{
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}
},
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}
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},
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}
},
{
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},
{
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}
},
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},
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},
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}
},
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},
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}
},
{
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},
{
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},
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},
{
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},
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},
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}
},
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}
},
{
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}
},
{
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},
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}
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},
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},
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},
{
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"fucacngalacglcgalgluside_hs_c":1.0,
"fucacngalacglcgalgluside_hs_e":-1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Extracellular",
"notes":{
"original_bigg_ids":[
"FUCACNGALACGLCGALGLUSIDEte"
]
},
"annotation":{
"bigg.reaction":[
"FUCACNGALACGLCGALGLUSIDEte"
],
"metanetx.reaction":[
"MNXR99682"
],
"sbo":"SBO:0000185"
}
},
{
"id":"FUCACNGALACGLCGALGLUSIDEtg",
"name":"Blood group intracellular transport",
"metabolites":{
"fucacngalacglcgalgluside_hs_c":1.0,
"fucacngalacglcgalgluside_hs_g":-1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Golgi Apparatus",
"notes":{
"original_bigg_ids":[
"FUCACNGALACGLCGALGLUSIDEtg"
]
},
"annotation":{
"bigg.reaction":[
"FUCACNGALACGLCGALGLUSIDEtg"
],
"metanetx.reaction":[
"MNXR99682"
],
"sbo":"SBO:0000185"
}
},
{
"id":"GALASE19ly",
"name":"Beta-galactosidase, lysosomal",
"metabolites":{
"core6_l":1.0,
"f1a_l":-1.0,
"gal_l":1.0,
"h2o_l":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"(2720_AT1 and 5476_AT1) or (2720_AT1 and 5476_AT1 and 4758_AT1 and 2588_AT1)",
"subsystem":"Keratan sulfate degradation",
"notes":{
"original_bigg_ids":[
"GALASE19ly"
]
},
"annotation":{
"bigg.reaction":[
"GALASE19ly"
],
"metanetx.reaction":[
"MNXR99943"
],
"sbo":"SBO:0000176"
}
},
{
"id":"GALASE1ly",
"name":"Beta-galactosidase, lysosomal",
"metabolites":{
"gal_l":2.0,
"h2o_l":-2.0,
"l2n2m2mn_l":-1.0,
"n2m2mn_l":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"(2720_AT1 and 5476_AT1 and 4758_AT1 and 2588_AT1) or (5476_AT1 and 2720_AT1)",
"subsystem":"N-Glycan Degradation",
"notes":{
"original_bigg_ids":[
"GALASE1ly"
]
},
"annotation":{
"bigg.reaction":[
"GALASE1ly"
],
"metanetx.reaction":[
"MNXR99944"
],
"sbo":"SBO:0000176"
}
},
{
"id":"FUCASE2e",
"name":"Alpha-fucosidase, extracellular",
"metabolites":{
"fuc__L_e":1.0,
"h2o_e":-1.0,
"ksi_deg1_e":1.0,
"ksi_e":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"2519_AT1",
"subsystem":"Keratan sulfate degradation",
"notes":{
"original_bigg_ids":[
"FUCASE2e"
]
},
"annotation":{
"bigg.reaction":[
"FUCASE2e"
],
"metanetx.reaction":[
"MNXR99685"
],
"sbo":"SBO:0000176"
}
},
{
"id":"G14T2g",
"name":"Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, Golgi",
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"ksii_core2_pre1_g":-1.0,
"ksii_core2_pre2_g":1.0,
"udp_g":1.0,
"udpgal_g":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"9334_AT1 or 8703_AT1 or 8704_AT2 or 2683_AT1 or 8704_AT1",
"subsystem":"Keratan sulfate biosynthesis",
"notes":{
"original_bigg_ids":[
"G14T2g"
]
},
"annotation":{
"bigg.reaction":[
"G14T2g"
],
"metanetx.reaction":[
"MNXR99814"
],
"sbo":"SBO:0000176"
}
},
{
"id":"GALASE20ly",
"name":"Beta-galactosidase, lysosomal",
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"h2o_l":-2.0,
"ksii_core4_deg2_l":-1.0,
"ksii_core4_deg3_l":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"(2720_AT1 and 5476_AT1) or (2588_AT1 and 5476_AT1 and 2720_AT1 and 4758_AT1)",
"subsystem":"Keratan sulfate degradation",
"notes":{
"original_bigg_ids":[
"GALASE20ly"
]
},
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],
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"MNXR99945"
],
"sbo":"SBO:0000176"
}
},
{
"id":"G14T3g",
"name":"Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, Golgi",
"metabolites":{
"h_g":1.0,
"ksii_core2_pre3_g":-1.0,
"ksii_core2_pre4_g":1.0,
"udp_g":1.0,
"udpgal_g":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"8704_AT2 or 9334_AT1 or 8703_AT1 or 8704_AT1 or 2683_AT1",
"subsystem":"Keratan sulfate biosynthesis",
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"original_bigg_ids":[
"G14T3g"
]
},
"annotation":{
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],
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GALASE3ly",
"name":"Beta-galactosidase, lysosomal",
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"h2o_l":-2.0,
"ksi_deg5_l":-1.0,
"ksi_deg6_l":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"(5476_AT1 and 2720_AT1 and 4758_AT1 and 2588_AT1) or (5476_AT1 and 2720_AT1)",
"subsystem":"Keratan sulfate degradation",
"notes":{
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]
},
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],
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GALASE4ly",
"name":"Beta-galactosidase, lysosomal",
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"h2o_l":-1.0,
"ksi_deg8_l":-1.0,
"ksi_deg9_l":1.0
},
"lower_bound":0.0,
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"subsystem":"Keratan sulfate degradation",
"notes":{
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]
},
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],
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"MNXR99947"
],
"sbo":"SBO:0000176"
}
},
{
"id":"GARFT",
"name":"Phosphoribosylglycinamide formyltransferase",
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"fgam_c":1.0,
"gar_c":-1.0,
"h_c":1.0,
"thf_c":1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"2618_AT1 or 2618_AT2",
"subsystem":"IMP Biosynthesis",
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]
},
"annotation":{
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],
"ec-code":[
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],
"kegg.reaction":[
"R04325"
],
"metanetx.reaction":[
"MNXR99623"
],
"rhea":[
"15053",
"15054",
"15055",
"15056"
],
"sbo":"SBO:0000176"
}
},
{
"id":"G14T4g",
"name":"Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, Golgi",
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"h_g":1.0,
"ksii_core2_pre6_g":-1.0,
"ksii_core2_pre7_g":1.0,
"udp_g":1.0,
"udpgal_g":-1.0
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"notes":{
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]
},
"annotation":{
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],
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GASNASE2ly",
"name":"Glycosylasparaginase, lysosomal",
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"h2o_l":-1.0,
"n2m2nm_l":1.0,
"n2m2nmasn_l":-1.0
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"lower_bound":0.0,
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]
},
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GASNASE3ly",
"name":"Glycosylasparaginase, lysosomal",
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"ksi_deg2_l":1.0
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"lower_bound":0.0,
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"subsystem":"Keratan sulfate degradation",
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},
"annotation":{
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],
"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GALASE5ly",
"name":"Beta-galactosidase, lysosomal",
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"h2o_l":-1.0,
"ksi_deg11_l":-1.0,
"ksi_deg12_l":1.0
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"lower_bound":0.0,
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"notes":{
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]
},
"annotation":{
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],
"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GALASE6ly",
"name":"Beta-galactosidase, lysosomal",
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"h2o_l":-1.0,
"ksi_deg14_l":-1.0,
"ksi_deg15_l":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"(5476_AT1 and 2720_AT1) or (2720_AT1 and 5476_AT1 and 4758_AT1 and 2588_AT1)",
"subsystem":"Keratan sulfate degradation",
"notes":{
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"GALASE6ly"
]
},
"annotation":{
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"GALASE6ly"
],
"metanetx.reaction":[
"MNXR99949"
],
"sbo":"SBO:0000176"
}
},
{
"id":"GALASE7ly",
"name":"Beta-galactosidase, lysosomal",
"metabolites":{
"gal_l":1.0,
"h2o_l":-1.0,
"ksi_deg17_l":-1.0,
"ksi_deg18_l":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"(5476_AT1 and 2720_AT1) or (2588_AT1 and 2720_AT1 and 5476_AT1 and 4758_AT1)",
"subsystem":"Keratan sulfate degradation",
"notes":{
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]
},
"annotation":{
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],
"metanetx.reaction":[
"MNXR99950"
],
"sbo":"SBO:0000176"
}
},
{
"id":"GALASE8ly",
"name":"Beta-galactosidase, lysosomal",
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"h2o_l":-1.0,
"ksi_deg20_l":-1.0,
"ksi_deg21_l":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"(5476_AT1 and 2720_AT1) or (2588_AT1 and 4758_AT1 and 5476_AT1 and 2720_AT1)",
"subsystem":"Keratan sulfate degradation",
"notes":{
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"GALASE8ly"
]
},
"annotation":{
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"GALASE8ly"
],
"metanetx.reaction":[
"MNXR99951"
],
"sbo":"SBO:0000176"
}
},
{
"id":"GALASE9ly",
"name":"Beta-galactosidase, lysosomal",
"metabolites":{
"gal_l":1.0,
"h2o_l":-1.0,
"ksi_deg23_l":-1.0,
"ksi_deg24_l":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"(5476_AT1 and 2720_AT1 and 4758_AT1 and 2588_AT1) or (2720_AT1 and 5476_AT1)",
"subsystem":"Keratan sulfate degradation",
"notes":{
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"GALASE9ly"
]
},
"annotation":{
"bigg.reaction":[
"GALASE9ly"
],
"metanetx.reaction":[
"MNXR99952"
],
"sbo":"SBO:0000176"
}
},
{
"id":"GALC",
"name":"Galactocerebrosidase",
"metabolites":{
"crm_hs_l":1.0,
"gal_l":1.0,
"galside_hs_l":-1.0,
"h2o_l":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"2581_AT1",
"subsystem":"Sphingolipid Metabolism",
"notes":{
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"GALC"
]
},
"annotation":{
"bigg.reaction":[
"GALC"
],
"metanetx.reaction":[
"MNXR99954"
],
"sbo":"SBO:0000176"
}
},
{
"id":"GASNASEly",
"name":"Glycosylasparaginase, lysosomal",
"metabolites":{
"Asn_X_Ser_Thr_l":1.0,
"h2o_l":-1.0,
"s2l2n2m2m_l":1.0,
"s2l2n2m2masn_l":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"175_AT1",
"subsystem":"N-Glycan Degradation",
"notes":{
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"GASNASEly"
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},
"annotation":{
"bigg.reaction":[
"GASNASEly"
],
"metanetx.reaction":[
"MNXR100045"
],
"sbo":"SBO:0000176"
}
},
{
"id":"GBA",
"name":"Glucosylceramidase",
"metabolites":{
"crm_hs_c":1.0,
"glc__D_c":1.0,
"gluside_hs_c":-1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"2629_AT4 or 2629_AT2 or 2629_AT1 or 2629_AT3 or 2629_AT5",
"subsystem":"Sphingolipid Metabolism",
"notes":{
"original_bigg_ids":[
"GBA"
]
},
"annotation":{
"bigg.reaction":[
"GBA"
],
"metanetx.reaction":[
"MNXR100050"
],
"sbo":"SBO:0000176"
}
},
{
"id":"GBAl",
"name":"Glucosylceramidase",
"metabolites":{
"crm_hs_l":1.0,
"glc__D_l":1.0,
"gluside_hs_l":-1.0,
"h2o_l":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"2629_AT2 or 2629_AT1 or 2629_AT3 or 2629_AT5 or 2629_AT4",
"subsystem":"Sphingolipid Metabolism",
"notes":{
"original_bigg_ids":[
"GBAl"
]
},
"annotation":{
"bigg.reaction":[
"GBAl"
],
"metanetx.reaction":[
"MNXR100050"
],
"sbo":"SBO:0000176"
}
},
{
"id":"GALFUC12GAL14ACGLCGALGLUSIDEte",
"name":"Blood group intracellular transport",
"metabolites":{
"galfuc12gal14acglcgalgluside_hs_c":1.0,
"galfuc12gal14acglcgalgluside_hs_e":-1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Extracellular",
"notes":{
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"GALFUC12GAL14ACGLCGALGLUSIDEte"
]
},
"annotation":{
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"GALFUC12GAL14ACGLCGALGLUSIDEte"
],
"metanetx.reaction":[
"MNXR99966"
],
"sbo":"SBO:0000185"
}
},
{
"id":"GALFUC12GAL14ACGLCGALGLUSIDEtg",
"name":"Blood group intracellular transport",
"metabolites":{
"galfuc12gal14acglcgalgluside_hs_c":1.0,
"galfuc12gal14acglcgalgluside_hs_g":-1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Golgi Apparatus",
"notes":{
"original_bigg_ids":[
"GALFUC12GAL14ACGLCGALGLUSIDEtg"
]
},
"annotation":{
"bigg.reaction":[
"GALFUC12GAL14ACGLCGALGLUSIDEtg"
],
"metanetx.reaction":[
"MNXR99966"
],
"sbo":"SBO:0000185"
}
},
{
"id":"GBGT1",
"name":"Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1",
"metabolites":{
"acgagbside_hs_g":1.0,
"gbside_hs_g":-1.0,
"h_g":1.0,
"udp_g":1.0,
"udpacgal_g":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"26301_AT1",
"subsystem":"Sphingolipid Metabolism",
"notes":{
"original_bigg_ids":[
"GBGT1"
]
},
"annotation":{
"bigg.reaction":[
"GBGT1"
],
"metanetx.reaction":[
"MNXR100055"
],
"sbo":"SBO:0000176"
}
},
{
"id":"GALFUCGALACGLCGAL14ACGLCGALGLUSIDEte",
"name":"Blood group intracellular transport",
"metabolites":{
"galfucgalacglcgal14acglcgalgluside_hs_c":1.0,
"galfucgalacglcgal14acglcgalgluside_hs_e":-1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Extracellular",
"notes":{
"original_bigg_ids":[
"GALFUCGALACGLCGAL14ACGLCGALGLUSIDEte"
]
},
"annotation":{
"bigg.reaction":[
"GALFUCGALACGLCGAL14ACGLCGALGLUSIDEte"
],
"metanetx.reaction":[
"MNXR99968"
],
"sbo":"SBO:0000185"
}
},
{
"id":"GBSIDEte",
"name":"Globoside transport",
"metabolites":{
"gbside_hs_c":-1.0,
"gbside_hs_e":1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Extracellular",
"notes":{
"original_bigg_ids":[
"GBSIDEte"
]
},
"annotation":{
"bigg.reaction":[
"GBSIDEte"
],
"metanetx.reaction":[
"MNXR100058"
],
"sbo":"SBO:0000185"
}
},
{
"id":"G14T5g",
"name":"Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, Golgi",
"metabolites":{
"h_g":1.0,
"ksii_core2_pre10_g":1.0,
"ksii_core2_pre9_g":-1.0,
"udp_g":1.0,
"udpgal_g":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"8703_AT1 or 9334_AT1 or 8704_AT2 or 2683_AT1 or 8704_AT1",
"subsystem":"Keratan sulfate biosynthesis",
"notes":{
"original_bigg_ids":[
"G14T5g"
]
},
"annotation":{
"bigg.reaction":[
"G14T5g"
],
"metanetx.reaction":[
"MNXR99817"
],
"sbo":"SBO:0000176"
}
},
{
"id":"GBSIDEtl",
"name":"Globoside intracellular transport",
"metabolites":{
"gbside_hs_c":-1.0,
"gbside_hs_l":1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Lysosomal",
"notes":{
"original_bigg_ids":[
"GBSIDEtl"
]
},
"annotation":{
"bigg.reaction":[
"GBSIDEtl"
],
"metanetx.reaction":[
"MNXR100058"
],
"sbo":"SBO:0000185"
}
},
{
"id":"GALFUCGALACGLCGAL14ACGLCGALGLUSIDEtg",
"name":"Blood group intracellular transport",
"metabolites":{
"galfucgalacglcgal14acglcgalgluside_hs_c":1.0,
"galfucgalacglcgal14acglcgalgluside_hs_g":-1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Golgi Apparatus",
"notes":{
"original_bigg_ids":[
"GALFUCGALACGLCGAL14ACGLCGALGLUSIDEtg"
]
},
"annotation":{
"bigg.reaction":[
"GALFUCGALACGLCGAL14ACGLCGALGLUSIDEtg"
],
"metanetx.reaction":[
"MNXR99968"
],
"sbo":"SBO:0000185"
}
},
{
"id":"GALGALFUCFUCGALACGLCGALACGLCGAL14ACGLCGALGLUSIDEte",
"name":"Blood group intracellular transport",
"metabolites":{
"galgalfucfucgalacglcgalacglcgal14acglcgalgluside_hs_c":1.0,
"galgalfucfucgalacglcgalacglcgal14acglcgalgluside_hs_e":-1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Extracellular",
"notes":{
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"GALGALFUCFUCGALACGLCGALACGLCGAL14ACGLCGALGLUSIDEte"
]
},
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"GALGALFUCFUCGALACGLCGALACGLCGAL14ACGLCGALGLUSIDEte"
],
"metanetx.reaction":[
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],
"sbo":"SBO:0000185"
}
},
{
"id":"GALGALFUCFUCGALACGLCGALACGLCGAL14ACGLCGALGLUSIDEtg",
"name":"Blood group intracellular transport",
"metabolites":{
"galgalfucfucgalacglcgalacglcgal14acglcgalgluside_hs_c":1.0,
"galgalfucfucgalacglcgalacglcgal14acglcgalgluside_hs_g":-1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
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"subsystem":"Transport, Golgi Apparatus",
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},
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"MNXR99970"
],
"sbo":"SBO:0000185"
}
},
{
"id":"GALGALGALTHCRMte",
"name":"Transport of Gal-Gal-Gal-Gal-Gal-Glc-Cer ",
"metabolites":{
"galgalgalthcrm_hs_c":-1.0,
"galgalgalthcrm_hs_e":1.0
},
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"sbo":"SBO:0000185"
}
},
{
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"name":"Glycolaldehyde dehydrogenase",
"metabolites":{
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"glyclt_c":1.0,
"h2o_c":-1.0,
"h_c":2.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"218_AT1 or 220_AT1 or 223_AT1 or 222_AT1 or 224_AT1 or 501_AT1 or 8854_AT2 or 8854_AT3 or 8854_AT1 or 221_AT1 or 216_AT1",
"subsystem":"Glyoxylate and Dicarboxylate Metabolism",
"notes":{
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]
},
"annotation":{
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"META:GLYCOLALD-DEHYDROG-RXN"
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"kegg.reaction":[
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],
"metanetx.reaction":[
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],
"rhea":[
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"20002",
"20001",
"20003"
],
"sabiork":[
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],
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"seed.reaction":[
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}
},
{
"id":"GCALDDm",
"name":"Glycolaldehyde dehydrogenase, mitochondrial",
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"glyclt_m":1.0,
"h2o_m":-1.0,
"h_m":2.0,
"nad_m":-1.0,
"nadh_m":1.0
},
"lower_bound":0.0,
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"gene_reaction_rule":"7915_AT1 or 8659_AT2 or 7915_AT2 or 217_AT1 or 8659_AT1 or 219_AT1 or 4329_AT1 or 5832_AT1",
"subsystem":"Glyoxylate and Dicarboxylate Metabolism",
"notes":{
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},
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"20003"
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"sbo":"SBO:0000176",
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]
}
},
{
"id":"GALGALGALTHCRMtg",
"name":"Galgalgalthcrm hs intracellular transport",
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"galgalgalthcrm_hs_g":1.0
},
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],
"sbo":"SBO:0000185"
}
},
{
"id":"G14T6g",
"name":"Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, Golgi",
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"ksi_pre3_g":1.0,
"udp_g":1.0,
"udpgal_g":-1.0
},
"lower_bound":0.0,
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"gene_reaction_rule":"2683_AT1 or 8704_AT1 or 8704_AT2 or 8703_AT1 or 9334_AT1",
"subsystem":"Keratan sulfate biosynthesis",
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]
},
"annotation":{
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],
"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GALGLUSIDEtg",
"name":"Galgluside hs intracellular transport",
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"galgluside_hs_g":1.0
},
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"upper_bound":999999.0,
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]
},
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],
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}
},
{
"id":"GCC2am",
"name":"Glycine cleavage complex  lipoamide   mitochondrial",
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"co2_m":1.0,
"gly_m":-1.0,
"h_m":-1.0,
"lpam_m":-1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"1738_AT1 and 2653_AT1 and 2731_AT1 and 275_AT1",
"subsystem":"Glycine, Serine, and Threonine Metabolism",
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]
},
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],
"sbo":"SBO:0000176",
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]
}
},
{
"id":"GCC2bim",
"name":"Glycine cleavage system  lipoamide  irreversible  mitochondrial",
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"dhlam_m":1.0,
"mlthf_m":1.0,
"nh4_m":1.0,
"thf_m":-1.0
},
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],
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}
},
{
"id":"GCC2cm",
"name":"Glycine cleavage complex  lipoamide   mitochondrial",
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"1.8.1"
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"33060",
"33062",
"33061"
],
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},
{
"id":"GALGLUSIDEtl",
"name":"Galgluside hs intracellular transport",
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"sbo":"SBO:0000185"
}
},
{
"id":"GALGT1",
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}
},
{
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"gm3_hs_g":-1.0,
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},
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GALGT3",
"name":"Beta-1,4 N-acetylgalactosaminyltransferase",
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"gd3_hs_g":-1.0,
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"metanetx.reaction":[
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"sbo":"SBO:0000176"
}
},
{
"id":"GALGT4",
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"sbo":"SBO:0000176"
}
},
{
"id":"GCCam",
"name":"Glycine cleavage complex  lipoylprotein   mitochondrial",
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},
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"kegg.reaction":[
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],
"metanetx.reaction":[
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],
"sabiork":[
"3223"
],
"sbo":"SBO:0000176",
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}
},
{
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"name":"Glycine cleavage complex  lipoylprotein  irreversible  mitochondrial",
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"dhlpro_m":1.0,
"mlthf_m":1.0,
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"thf_m":-1.0
},
"lower_bound":0.0,
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"subsystem":"Glycine, Serine, and Threonine Metabolism",
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},
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],
"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"G14T7g",
"name":"Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, Golgi",
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"ksi_pre6_g":1.0,
"udp_g":1.0,
"udpgal_g":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"8704_AT1 or 2683_AT1 or 8704_AT2 or 8703_AT1 or 9334_AT1",
"subsystem":"Keratan sulfate biosynthesis",
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},
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"sbo":"SBO:0000176"
}
},
{
"id":"GCCcm",
"name":"Glycine cleavage complex  lipoylprotein   mitochondrial",
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"h_m":1.0,
"lpro_m":1.0,
"nad_m":-1.0,
"nadh_m":1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"1738_AT1 and 2653_AT1 and 2731_AT1 and 275_AT1",
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],
"sbo":"SBO:0000176",
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}
},
{
"id":"GCHOLAt",
"name":"Glycocholate transport via bicarbonate countertransport",
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"gchola_e":-1.0,
"hco3_c":-1.0,
"hco3_e":1.0
},
"lower_bound":-999999.0,
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"gene_reaction_rule":"28234_AT1 or 10599_AT1 or 6579_AT1",
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},
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}
},
{
"id":"GCHOLAt2",
"name":"Glycocholate transport via sodium cotransport",
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"gchola_e":-1.0,
"na1_c":2.0,
"na1_e":-2.0
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"subsystem":"Transport, Extracellular",
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"metanetx.reaction":[
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],
"sbo":"SBO:0000185"
}
},
{
"id":"GALKr",
"name":"Galactokinase",
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"atp_c":-1.0,
"gal1p_c":1.0,
"gal_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"2585_AT2 or 2584_AT1 or 2585_AT1",
"subsystem":"Galactose metabolism",
"notes":{
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},
"annotation":{
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"biocyc":[
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"metanetx.reaction":[
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],
"rhea":[
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"13554",
"13555",
"13553"
],
"sabiork":[
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],
"sbo":"SBO:0000176",
"seed.reaction":[
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}
},
{
"id":"GALNACT1g",
"name":"UDPGal-chondroitin acetylgalactosaminyltransferase I, Golgi",
"metabolites":{
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"cs_pre_g":1.0,
"h_g":1.0,
"udp_g":1.0,
"udpacgal_g":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"55790_AT1 or 55454_AT1",
"subsystem":"Chondroitin / heparan sulfate biosynthesis",
"notes":{
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]
},
"annotation":{
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"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GALNACT2g",
"name":"Uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase II, Golgi",
"metabolites":{
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"cs_a_b_pre3_g":1.0,
"h_g":1.0,
"uacgam_g":-1.0,
"udp_g":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"55454_AT1 or 55790_AT1 or 337876_AT1 or (22856_AT1 and 79586_AT1)",
"subsystem":"Chondroitin / heparan sulfate biosynthesis",
"notes":{
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]
},
"annotation":{
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"GALNACT2g"
],
"metanetx.reaction":[
"MNXR99997"
],
"sbo":"SBO:0000176"
}
},
{
"id":"GALNACT3g",
"name":"Uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase II, Golgi",
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"cs_c_pre3_g":1.0,
"h_g":1.0,
"uacgam_g":-1.0,
"udp_g":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"(79586_AT1 and 22856_AT1) or 337876_AT1 or 55454_AT1 or 55790_AT1",
"subsystem":"Chondroitin / heparan sulfate biosynthesis",
"notes":{
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"GALNACT3g"
]
},
"annotation":{
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"GALNACT3g"
],
"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GALNACT4g",
"name":"Uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase II, Golgi",
"metabolites":{
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"cs_d_pre4_g":1.0,
"h_g":1.0,
"uacgam_g":-1.0,
"udp_g":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"55454_AT1 or 55790_AT1 or (22856_AT1 and 79586_AT1) or 337876_AT1",
"subsystem":"Chondroitin / heparan sulfate biosynthesis",
"notes":{
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]
},
"annotation":{
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],
"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GCHOLAt3",
"name":"ABC bile acid transporter",
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"atp_c":-1.0,
"gchola_c":-1.0,
"gchola_e":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"8647_AT1 or 8714_AT1 or 8714_AT3 or 8714_AT2",
"subsystem":"Transport, Extracellular",
"notes":{
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]
},
"annotation":{
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],
"sbo":"SBO:0000185"
}
},
{
"id":"G14T8g",
"name":"Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, Golgi",
"metabolites":{
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"ksi_pre8_g":-1.0,
"ksi_pre9_g":1.0,
"udp_g":1.0,
"udpgal_g":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"8704_AT1 or 2683_AT1 or 8704_AT2 or 8703_AT1 or 9334_AT1",
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"6dhf_e":1.0,
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"glu__L_e":1.0,
"h2o_e":-1.0
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"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"8836_AT1",
"subsystem":"Folate Metabolism",
"notes":{
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"GGH_7DHFe"
]
},
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],
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"MNXR100124"
],
"sbo":"SBO:0000176"
}
},
{
"id":"GGH_7DHFl",
"name":"Gamma-glutamyl hydrolase (7DHF), lysosomal",
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],
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}
},
{
"id":"GLCAASE4ly",
"name":"Beta-glucuronidase, lysosomal",
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"subsystem":"Chondroitin sulfate degradation",
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],
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}
},
{
"id":"GLCAASE5ly",
"name":"Beta-glucuronidase, lysosomal",
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}
},
{
"id":"GGH_7THFe",
"name":"Gamma-glutamyl hydrolase (7THF), extracellular",
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},
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],
"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"G1M7MASNCterg",
"name":"G1m7masnC endoplasmic reticulum to Golgi transport",
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],
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}
},
{
"id":"GGH_7THFl",
"name":"Gamma-glutamyl hydrolase (7THF), lysosomal",
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"metanetx.reaction":[
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"sbo":"SBO:0000176"
}
},
{
"id":"GGLUCT",
"name":"Gamma-glutamylcyclotransferase",
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"ala__L_c":1.0,
"gluala_e":-1.0
},
"lower_bound":0.0,
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"gene_reaction_rule":"2655_AT1",
"subsystem":"Glutathione Metabolism",
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],
"sbo":"SBO:0000185"
}
},
{
"id":"GGNG",
"name":"Glycogenin self-glucosylation",
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"ggn_c":1.0,
"h_c":8.0,
"udp_c":8.0,
"udpg_c":-8.0
},
"lower_bound":0.0,
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"gene_reaction_rule":"(2992_AT1 and 2998_AT1) or (2997_AT1 and 8908_AT1) or (8908_AT1 and 2998_AT1) or (2992_AT1 and 2997_AT1)",
"subsystem":"Starch and Sucrose Metabolism",
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"sbo":"SBO:0000176"
}
},
{
"id":"GGT5r",
"name":"Gamma-glutamyltransferase 5",
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"h2o_r":-1.0,
"leuktrC4_r":-1.0,
"leuktrD4_r":1.0
},
"lower_bound":-999999.0,
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"gene_reaction_rule":"2687_AT1",
"subsystem":"Eicosanoid Metabolism",
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]
},
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],
"metanetx.reaction":[
"MNXR100134"
],
"sbo":"SBO:0000176"
}
},
{
"id":"GGT6",
"name":"Gamma-glutamyltransferase",
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"h2o_c":1.0,
"leuktrE4_c":-1.0,
"leuktrF4_c":1.0
},
"lower_bound":-999999.0,
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"gene_reaction_rule":"",
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]
},
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],
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"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GGT_L",
"name":"Geranylgeranyltransferase (liver)",
"metabolites":{
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"ipdp_c":-17.6,
"ppi_c":17.6,
"ttc_ggdp_c":-1.0
},
"lower_bound":0.0,
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]
},
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],
"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GLCAASE6ly",
"name":"Beta-glucuronidase, lysosomal",
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"h2o_l":-1.0
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"subsystem":"Chondroitin sulfate degradation",
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]
},
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],
"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GLCAASE7ly",
"name":"Beta-glucuronidase, lysosomal",
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]
},
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"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GLCAASE8ly",
"name":"Beta-glucuronidase, lysosomal",
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"h2o_l":-1.0,
"ha_deg1_l":1.0,
"ha_l":-1.0
},
"lower_bound":0.0,
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"subsystem":"Hyaluronan Metabolism",
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"GLCAASE8ly"
]
},
"annotation":{
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],
"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GLCAASE9ly",
"name":"Beta-glucuronidase, lysosomal",
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"glcur_l":1.0,
"h2o_l":-2.0,
"ha_pre1_l":-1.0
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]
},
"annotation":{
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],
"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GLCAE1g",
"name":"Chondroitin-glucuronate 5-epimerase",
"metabolites":{
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"cs_b_pre4_g":1.0
},
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"subsystem":"Chondroitin / heparan sulfate biosynthesis",
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]
},
"annotation":{
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],
"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GLCAE2g",
"name":"Heparosan-N-sulfate-glucuronate 5-epimerase",
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"hs_pre11_g":1.0
},
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"subsystem":"Chondroitin / heparan sulfate biosynthesis",
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]
},
"annotation":{
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GLCAT2g",
"name":"Chondroitin glucuronyltransferase II, Golgi apparatus",
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"h_g":1.0,
"udp_g":1.0,
"udpglcur_g":-1.0
},
"lower_bound":0.0,
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"metanetx.reaction":[
"MNXR100166"
],
"sbo":"SBO:0000176"
}
},
{
"id":"GLCAT3g",
"name":"Chondroitin glucuronyltransferase II, Golgi apparatus",
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"h_g":1.0,
"udp_g":1.0,
"udpglcur_g":-1.0
},
"lower_bound":0.0,
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]
},
"annotation":{
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],
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GLCAT4g",
"name":"Chondroitin glucuronyltransferase II, Golgi apparatus",
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"cs_d_pre3_g":1.0,
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"udp_g":1.0,
"udpglcur_g":-1.0
},
"lower_bound":0.0,
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},
"annotation":{
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],
"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GGT_U",
"name":"Geranylgeranyltransferase (uterus)",
"metabolites":{
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"ipdp_c":-16.5,
"ppi_c":16.5,
"ttc_ggdp_c":-1.0
},
"lower_bound":0.0,
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"gene_reaction_rule":"",
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]
},
"annotation":{
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],
"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GHMT2r",
"name":"Glycine hydroxymethyltransferase, reversible",
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"h2o_c":1.0,
"mlthf_c":1.0,
"ser__L_c":-1.0,
"thf_c":-1.0
},
"lower_bound":-999999.0,
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"gene_reaction_rule":"6470_AT2 or 6470_AT1",
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},
"annotation":{
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],
"ec-code":[
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"kegg.reaction":[
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],
"metanetx.reaction":[
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],
"rhea":[
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"15483",
"15484",
"15482"
],
"sbo":"SBO:0000176"
}
},
{
"id":"GHMT2rm",
"name":"Glycine hydroxymethyltransferase  reversible  mitochondrial",
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"h2o_m":1.0,
"mlthf_m":1.0,
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"thf_m":-1.0
},
"lower_bound":-999999.0,
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],
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"15483",
"15484",
"15482"
],
"sbo":"SBO:0000176"
}
},
{
"id":"G1M8MASNterg",
"name":"G1m8masn transport from endoplasmic reticulum to Golgi apparatus",
"metabolites":{
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"g1m8masn_r":-1.0
},
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},
"annotation":{
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"metanetx.reaction":[
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],
"sbo":"SBO:0000185"
}
},
{
"id":"GHMT3",
"name":"Glycine hydroxymethyltransferase",
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"4tmeabut_c":1.0,
"gly_c":1.0,
"h_c":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
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"subsystem":"Lysine Metabolism",
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},
"annotation":{
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"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GLCAT5g",
"name":"Chondroitin glucuronyltransferase II, Golgi apparatus",
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"udp_g":1.0,
"udpglcur_g":-1.0
},
"lower_bound":0.0,
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},
"annotation":{
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"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GLCAT6g",
"name":"Heparan glucuronyltransferase II",
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"hs_pre1_g":-1.0,
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"udp_g":1.0,
"udpglcur_g":-1.0
},
"lower_bound":0.0,
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},
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"metanetx.reaction":[
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],
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}
},
{
"id":"GLCAT7g",
"name":"Heparan glucuronyltransferase II",
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"hs_pre4_g":1.0,
"udp_g":1.0,
"udpglcur_g":-1.0
},
"lower_bound":0.0,
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]
},
"annotation":{
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"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"G1PTT",
"name":"Glucose-1-phosphate thymidylyltransferase",
"metabolites":{
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"dttp_c":-1.0,
"g1p_c":-1.0,
"h_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Nucleotide Sugar Metabolism",
"notes":{
"original_bigg_ids":[
"G1PTT"
]
},
"annotation":{
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],
"biocyc":[
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],
"ec-code":[
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],
"kegg.reaction":[
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],
"metanetx.reaction":[
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],
"rhea":[
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"15227",
"15225",
"15228"
],
"sabiork":[
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],
"sbo":"SBO:0000176",
"seed.reaction":[
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]
}
},
{
"id":"GLCAT8g",
"name":"Heparan glucuronyltransferase II",
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},
"lower_bound":0.0,
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"subsystem":"Chondroitin / heparan sulfate biosynthesis",
"notes":{
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},
"annotation":{
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"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"GLCAT9g",
"name":"Heparan glucuronyltransferase II",
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"hs_pre8_g":1.0,
"udp_g":1.0,
"udpglcur_g":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"(2132_AT1 and 2131_AT1) or (2131_AT1 and 2132_AT2)",
"subsystem":"Chondroitin / heparan sulfate biosynthesis",
"notes":{
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},
"annotation":{
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"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
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],
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"META:TRANS-RXN0-562"
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],
"sbo":"SBO:0000185",
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"rxn08737",
"rxn08738"
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},
{
"id":"Htm",
"name":"Uncoupling protein",
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"upper_bound":999999.0,
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"R-DRE-74723",
"R-HSA-170026",
"R-TGU-2534378",
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"R-TGU-74723",
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"R-GGA-2534378",
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"R-BTA-2534378",
"R-SSC-2534378",
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"R-TGU-170026",
"R-GGA-170026",
"R-SCE-170026",
"R-DRE-2534378",
"R-BTA-74723",
"R-SPO-74723",
"R-XTR-74723",
"R-RNO-74723",
"R-XTR-2534378",
"R-MMU-74723",
"R-CFA-74723",
"R-GGA-74723",
"R-CEL-170026",
"R-MMU-170026",
"R-ATH-74723",
"R-DME-74723",
"R-PFA-74723",
"R-SSC-74723",
"R-XTR-170026",
"R-SSC-170026",
"R-CEL-74723",
"R-ATH-170026",
"R-RNO-170026",
"R-DME-170026"
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"34981",
"34982",
"34979"
],
"sbo":"SBO:0000185",
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"rxn08730"
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}
},
{
"id":"LNELDCCPT2",
"name":"Carnitine transferase",
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"crn_m":1.0,
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"lneldccrn_m":-1.0
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]
},
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],
"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"Htr",
"name":"H transporter, endoplasmic reticulum",
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"h_c":-1.0,
"h_r":1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
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"subsystem":"Transport, Endoplasmic Reticular",
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},
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],
"biocyc":[
"META:RXN-14452"
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"R-DDI-74723",
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"R-HSA-170026",
"R-TGU-2534378",
"R-HSA-74723",
"R-CFA-2534378",
"R-TGU-74723",
"R-OSA-170026",
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"R-GGA-2534378",
"R-MMU-2534378",
"R-BTA-2534378",
"R-SSC-2534378",
"R-DRE-170026",
"R-TGU-170026",
"R-GGA-170026",
"R-SCE-170026",
"R-DRE-2534378",
"R-BTA-74723",
"R-SPO-74723",
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"R-MMU-74723",
"R-CFA-74723",
"R-GGA-74723",
"R-CEL-170026",
"R-MMU-170026",
"R-ATH-74723",
"R-DME-74723",
"R-PFA-74723",
"R-SSC-74723",
"R-XTR-170026",
"R-SSC-170026",
"R-CEL-74723",
"R-ATH-170026",
"R-RNO-170026",
"R-DME-170026"
],
"rhea":[
"34980",
"34981",
"34982",
"34979"
],
"sbo":"SBO:0000185",
"seed.reaction":[
"rxn11009",
"rxn08730"
]
}
},
{
"id":"LNELDCCRNt",
"name":"Transport into the mitochondria (carnitine)",
"metabolites":{
"lneldccrn_c":-1.0,
"lneldccrn_m":1.0
},
"lower_bound":0.0,
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"gene_reaction_rule":"788_AT1",
"subsystem":"Carnitine shuttle",
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]
},
"annotation":{
"bigg.reaction":[
"LNELDCCRNt"
],
"metanetx.reaction":[
"MNXR101102"
],
"sbo":"SBO:0000185"
}
},
{
"id":"KAS8",
"name":"B-ketoacyl synthetase (palmitate, n-C16:0)",
"metabolites":{
"accoa_c":-1.0,
"co2_c":7.0,
"coa_c":8.0,
"h2o_c":6.0,
"h_c":-20.0,
"hdca_c":1.0,
"malcoa_c":-7.0,
"nadp_c":14.0,
"nadph_c":-14.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"2194_AT1",
"subsystem":"Fatty acid elongation",
"notes":{
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"KAS8"
]
},
"annotation":{
"bigg.reaction":[
"KAS8"
],
"ec-code":[
"2.3.1.85",
"2.3.1.41"
],
"metanetx.reaction":[
"MNXR100924"
],
"reactome.reaction":[
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"R-CEL-75872",
"R-HSA-75872",
"R-BTA-75872",
"R-SCE-75872",
"R-DRE-75872",
"R-TGU-75872",
"R-DME-75872",
"R-XTR-75872",
"R-SSC-75872",
"R-GGA-75872",
"R-CFA-75872",
"R-MMU-75872"
],
"sabiork":[
"6701"
],
"sbo":"SBO:0000176",
"seed.reaction":[
"rxn05291"
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}
},
{
"id":"LNELDCt",
"name":"Fatty acid transport via diffusion",
"metabolites":{
"lneldc_c":1.0,
"lneldc_e":-1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Extracellular",
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},
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],
"metanetx.reaction":[
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],
"sbo":"SBO:0000185"
}
},
{
"id":"LNLCCPT1",
"name":"Carnitine O-palmitoyltransferase",
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"lnlccoa_c":-1.0,
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"lower_bound":0.0,
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"gene_reaction_rule":"1375_AT4 or 1374_AT1 or 126129_AT1 or 1375_AT1 or 1375_AT3 or 1375_AT2",
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"sbo":"SBO:0000176"
}
},
{
"id":"Htx",
"name":"H transporter, peroxisome",
"metabolites":{
"h_c":-1.0,
"h_x":1.0
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"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Peroxisomal",
"notes":{
"original_bigg_ids":[
"Htx"
]
},
"annotation":{
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"biocyc":[
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"R-DDI-74723",
"R-BTA-170026",
"R-CFA-170026",
"R-SCE-74723",
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"R-HSA-170026",
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"R-TGU-74723",
"R-OSA-170026",
"R-RNO-2534378",
"R-GGA-2534378",
"R-MMU-2534378",
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"R-SSC-2534378",
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"R-XTR-2534378",
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"R-CFA-74723",
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"R-MMU-170026",
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"R-DME-74723",
"R-PFA-74723",
"R-SSC-74723",
"R-XTR-170026",
"R-SSC-170026",
"R-CEL-74723",
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"R-RNO-170026",
"R-DME-170026"
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"34980",
"34981",
"34982",
"34979"
],
"sbo":"SBO:0000185",
"seed.reaction":[
"rxn11009",
"rxn08730"
]
}
},
{
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"co2_m":1.0,
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"nad_m":-1.0,
"nadh_m":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
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},
"annotation":{
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"1.1.1.41"
],
"kegg.reaction":[
"R00709"
],
"metanetx.reaction":[
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],
"sabiork":[
"270"
],
"sbo":"SBO:0000176",
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]
}
},
{
"id":"LNLCCPT2",
"name":"Carnitine transferase",
"metabolites":{
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"crn_m":1.0,
"lnlccoa_m":1.0,
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"lower_bound":0.0,
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"subsystem":"Carnitine shuttle",
"notes":{
"original_bigg_ids":[
"LNLCCPT2"
]
},
"annotation":{
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"LNLCCPT2"
],
"metanetx.reaction":[
"MNXR101105"
],
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}
},
{
"id":"ICDHyr",
"name":"Isocitrate dehydrogenase (NADP)",
"metabolites":{
"akg_c":1.0,
"co2_c":1.0,
"icit_c":-1.0,
"nadp_c":-1.0,
"nadph_c":1.0
},
"lower_bound":0.0,
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"ICDHy"
]
},
"annotation":{
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],
"ec-code":[
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],
"kegg.reaction":[
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"19630",
"19631",
"19632"
],
"sabiork":[
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],
"sbo":"SBO:0000176",
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"rxn00198"
]
}
},
{
"id":"LNLCCRNt",
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"lnlccrn_m":1.0
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"subsystem":"Carnitine shuttle",
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],
"metanetx.reaction":[
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},
{
"id":"KCC2t",
"name":"K+-Cl- cotransporter (NH4+)",
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"nh4_c":1.0,
"nh4_e":-1.0
},
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},
{
"id":"LNLCt",
"name":"Linoleic acid (n-C18:2) transport in via diffusion",
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"lnlc_e":-1.0
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"lower_bound":-999999.0,
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]
},
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"45266",
"45265",
"45264"
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}
},
{
"id":"LNLNCACPT1",
"name":"Carnitine O-palmitoyltransferase",
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"crn_c":-1.0,
"lnlncacoa_c":-1.0,
"lnlncacrn_c":1.0
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"lower_bound":0.0,
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"subsystem":"Carnitine shuttle",
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},
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},
{
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"crn_m":1.0,
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}
},
{
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"co2_x":1.0,
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},
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}
},
{
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"sabiork":[
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],
"sbo":"SBO:0000176",
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}
},
{
"id":"IDHPOXOX2b",
"name":"Iodide:hydrogen-peroxide oxidoreductase 2",
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"3ityr__L_c":-1.0,
"h_c":1.0,
"i_c":1.0,
"iodine_c":-1.0
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},
"annotation":{
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},
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"triodthy_c":1.0
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"lower_bound":0.0,
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}
},
{
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"tyr__L_c":-1.0
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"lower_bound":0.0,
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},
{
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"name":"Alpha-L-iduronidase, lysosomal",
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"hs_deg4_l":-1.0,
"hs_deg5_l":1.0,
"idour_l":1.0
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"lower_bound":0.0,
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]
},
"annotation":{
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],
"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"N2M2NMASNt",
"name":"N2m2nmasn transport, Golgi to extracellular",
"metabolites":{
"n2m2nmasn_e":1.0,
"n2m2nmasn_g":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Extracellular",
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]
},
"annotation":{
"bigg.reaction":[
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],
"metanetx.reaction":[
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],
"sbo":"SBO:0000185"
}
},
{
"id":"N2M2NMASNtly",
"name":"N2m2nmasn transport, extracellular to lysosome",
"metabolites":{
"n2m2nmasn_e":-1.0,
"n2m2nmasn_l":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Lysosomal",
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]
},
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"bigg.reaction":[
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],
"metanetx.reaction":[
"MNXR101795"
],
"sbo":"SBO:0000185"
}
},
{
"id":"NACHEXA9ly",
"name":"Beta-N-acetylhexosaminidase A, lysosomal",
"metabolites":{
"acgam_l":2.0,
"h2o_l":-3.0,
"h_l":1.0,
"ksi_deg6_l":-1.0,
"ksi_deg8_l":1.0,
"so4_l":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"(3073_AT1 and 3074_AT1) or 3073_AT1",
"subsystem":"Keratan sulfate degradation",
"notes":{
"original_bigg_ids":[
"NACHEXA9ly"
]
},
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],
"metanetx.reaction":[
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],
"sbo":"SBO:0000176"
}
},
{
"id":"N3Tg",
"name":"N-acetylgalactosamine 3-beta-galactosyltransferase, Golgi apparatus",
"metabolites":{
"T_antigen_g":1.0,
"Tn_antigen_g":-1.0,
"h_g":1.0,
"udp_g":1.0,
"udpgal_g":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"56913_AT1",
"subsystem":"O-Glycan Biosynthesis",
"notes":{
"original_bigg_ids":[
"N3Tg"
]
},
"annotation":{
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],
"ec-code":[
"2.4.1.122"
],
"kegg.reaction":[
"R05908"
],
"metanetx.reaction":[
"MNXR101800"
],
"sbo":"SBO:0000176"
}
},
{
"id":"LCYSTATm",
"name":"Aspartate aminotransferase, cysteate forming, mitochondria",
"metabolites":{
"3spyr_m":1.0,
"Lcyst_m":-1.0,
"akg_m":-1.0,
"glu__L_m":1.0
},
"lower_bound":-999999.0,
"upper_bound":999999.0,
"gene_reaction_rule":"2806_AT1",
"subsystem":"Cysteine Metabolism",
"notes":{
"original_bigg_ids":[
"LCYSTATm"
]
},
"annotation":{
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],
"biocyc":[
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],
"ec-code":[
"2.6.1.1"
],
"kegg.reaction":[
"R02433"
],
"metanetx.reaction":[
"MNXR95161"
],
"sbo":"SBO:0000176",
"seed.reaction":[
"rxn01757"
]
}
},
{
"id":"N4Tg",
"name":"N-acetylgalactosamine 4-beta-galactosyltransferase, Golgi apparatus",
"metabolites":{
"core6_g":-1.0,
"f1a_g":1.0,
"h_g":1.0,
"udp_g":1.0,
"udpgal_g":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"O-Glycan Biosynthesis",
"notes":{
"original_bigg_ids":[
"N4Tg"
]
},
"annotation":{
"bigg.reaction":[
"N4Tg"
],
"metanetx.reaction":[
"MNXR101801"
],
"sbo":"SBO:0000176"
}
},
{
"id":"NABTNO",
"name":"N4 AcetylaminobutanalNAD oxidoreductase",
"metabolites":{
"4aabutn_c":1.0,
"h2o_c":-1.0,
"h_c":2.0,
"n4abutn_c":-1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"8854_AT3 or 223_AT1 or 216_AT1 or 8854_AT1 or 501_AT1 or 224_AT1 or 8854_AT2",
"subsystem":"Arginine and Proline Metabolism",
"notes":{
"original_bigg_ids":[
"NABTNO"
]
},
"annotation":{
"bigg.reaction":[
"NABTNO"
],
"biocyc":[
"META:RXN-37"
],
"ec-code":[
"1.2.1.3"
],
"kegg.reaction":[
"R05050"
],
"metanetx.reaction":[
"MNXR101805"
],
"rhea":[
"31233",
"31234",
"31231",
"31232"
],
"sabiork":[
"4679"
],
"sbo":"SBO:0000176",
"seed.reaction":[
"rxn03423"
]
}
},
{
"id":"LCYSTCBOXL",
"name":"3-Sulfoalanine carboxy-lyase",
"metabolites":{
"Lcyst_c":-1.0,
"co2_c":1.0,
"h_c":-1.0,
"taur_c":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"2571_AT1 or 2571_AT2 or 2572_AT1 or 51380_AT1",
"subsystem":"Taurine and hypotaurine metabolism",
"notes":{
"original_bigg_ids":[
"LCYSTCBOXL"
]
},
"annotation":{
"bigg.reaction":[
"LCYSTCBOXL"
],
"biocyc":[
"META:CYSTAUR-RXN"
],
"ec-code":[
"4.1.1.15",
"4.1.1.29"
],
"kegg.reaction":[
"R01682"
],
"metanetx.reaction":[
"MNXR101032"
],
"rhea":[
"25222",
"25221",
"25224",
"25223"
],
"sbo":"SBO:0000176",
"seed.reaction":[
"rxn01231"
]
}
},
{
"id":"NABTNOm",
"name":"N4-Acetylaminobutanal:NAD+ oxidoreductase (m)",
"metabolites":{
"4aabutn_m":1.0,
"h2o_m":-1.0,
"h_m":2.0,
"n4abutn_m":-1.0,
"nad_m":-1.0,
"nadh_m":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"8659_AT1 or 219_AT1 or 217_AT1",
"subsystem":"Arginine and Proline Metabolism",
"notes":{
"original_bigg_ids":[
"NABTNOm"
]
},
"annotation":{
"bigg.reaction":[
"NABTNOm"
],
"biocyc":[
"META:RXN-37"
],
"ec-code":[
"1.2.1.3"
],
"kegg.reaction":[
"R05050"
],
"metanetx.reaction":[
"MNXR101805"
],
"rhea":[
"31233",
"31234",
"31231",
"31232"
],
"sabiork":[
"4679"
],
"sbo":"SBO:0000176",
"seed.reaction":[
"rxn03423"
]
}
},
{
"id":"NACASPAH",
"name":"N-Acetyl-L-aspartate amidohydrolase",
"metabolites":{
"Nacasp_c":-1.0,
"ac_c":1.0,
"asp__L_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"443_AT1 or 91703_AT1",
"subsystem":"Alanine and Aspartate Metabolism",
"notes":{
"original_bigg_ids":[
"NACASPAH"
]
},
"annotation":{
"bigg.reaction":[
"NACASPAH"
],
"biocyc":[
"META:RXN-13680"
],
"ec-code":[
"3.5.1.15",
"3.5.1.14"
],
"kegg.reaction":[
"R00488"
],
"metanetx.reaction":[
"MNXR106555"
],
"reactome.reaction":[
"R-RNO-5691507",
"R-BTA-5691507",
"R-CFA-5691507",
"R-TGU-5691507",
"R-SSC-5691507",
"R-GGA-5691507",
"R-XTR-5691507",
"R-DRE-5691507",
"R-HSA-5691507",
"R-MMU-5691507"
],
"sabiork":[
"920"
],
"sbo":"SBO:0000176",
"seed.reaction":[
"rxn00345"
]
}
},
{
"id":"NACt",
"name":"Nicotinic acid transport",
"metabolites":{
"nac_c":1.0,
"nac_e":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Extracellular",
"notes":{
"original_bigg_ids":[
"NACUP"
]
},
"annotation":{
"bigg.reaction":[
"NACt"
],
"metanetx.reaction":[
"MNXR101808"
],
"reactome.reaction":[
"R-TGU-8869603",
"R-BTA-8869603",
"R-XTR-8869603",
"R-CFA-8869603",
"R-GGA-8869603",
"R-RNO-8869603",
"R-HSA-8869603",
"R-DME-8869603",
"R-SSC-8869603",
"R-MMU-8869603",
"R-DRE-8869603"
],
"sbo":"SBO:0000185",
"seed.reaction":[
"rxn08970",
"rxn05310",
"rxn08969"
]
}
},
{
"id":"NADH2_u10m",
"name":"NADH dehydrogenase, mitochondrial",
"metabolites":{
"h_c":4.0,
"h_m":-5.0,
"nad_m":1.0,
"nadh_m":-1.0,
"q10_m":-1.0,
"q10h2_m":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"(4698_AT1 and 4701_AT1 and 4724_AT1 and 4538_AT1 and 4540_AT1 and 4717_AT1 and 126328_AT1 and 4719_AT1 and 4714_AT1 and 4713_AT1 and 4723_AT1 and 4715_AT1 and 4710_AT1 and 4700_AT1 and 4535_AT1 and 4539_AT1 and 4702_AT1 and 4731_AT1 and 4711_AT1 and 4706_AT1 and 4541_AT1 and 7991_AT2 and 4537_AT1 and 4705_AT1 and 4704_AT1 and 51079_AT1 and 374291_AT1 and 4722_AT1 and 4536_AT1 and 4712_AT2 and 4716_AT1 and 4725_AT1 and 4707_AT1 and 4694_AT1 and 4718_AT1 and 4726_AT1 and 4696_AT1 and 4708_AT1 and 4720_AT1 and 4728_AT1 and 4709_AT1 and 4697_AT1 and 4695_AT1 and 55967_AT1 and 4729_AT1) or (4728_AT1 and 4708_AT1 and 4720_AT1 and 55967_AT1 and 4695_AT1 and 4729_AT1 and 4709_AT1 and 4697_AT1 and 51079_AT1 and 7991_AT1 and 374291_AT1 and 4536_AT1 and 4722_AT1 and 4731_AT2 and 4537_AT1 and 4705_AT1 and 4704_AT1 and 4707_AT1 and 4694_AT1 and 4718_AT1 and 4726_AT1 and 4696_AT1 and 4712_AT2 and 4716_AT1 and 4725_AT1 and 4713_AT1 and 4723_AT1 and 4714_AT1 and 4535_AT1 and 4539_AT1 and 4702_AT1 and 4711_AT1 and 4541_AT1 and 4706_AT1 and 4715_AT1 and 4710_AT1 and 4700_AT1 and 4538_AT1 and 4540_AT1 and 126328_AT1 and 4717_AT1 and 4698_AT1 and 4724_AT1 and 4701_AT1 and 4719_AT1) or (4715_AT1 and 4710_AT1 and 4700_AT1 and 4535_AT1 and 4539_AT1 and 4702_AT1 and 4706_AT1 and 4711_AT1 and 4541_AT1 and 4714_AT1 and 4713_AT1 and 4723_AT1 and 4719_AT1 and 4698_AT1 and 4724_AT1 and 4701_AT1 and 4538_AT1 and 4540_AT1 and 4717_AT1 and 126328_AT1 and 4709_AT1 and 4697_AT1 and 4695_AT1 and 55967_AT1 and 4729_AT1 and 4720_AT1 and 4708_AT1 and 4728_AT1 and 4712_AT2 and 4716_AT1 and 4725_AT1 and 4694_AT1 and 4718_AT1 and 4707_AT1 and 4726_AT1 and 4696_AT1 and 7991_AT2 and 4731_AT2 and 4537_AT1 and 4704_AT1 and 4705_AT1 and 51079_AT1 and 374291_AT1 and 4722_AT1 and 4536_AT1) or (4719_AT1 and 4538_AT1 and 126328_AT1 and 4717_AT1 and 4540_AT1 and 4698_AT1 and 4701_AT1 and 4724_AT1 and 4702_AT1 and 4535_AT1 and 4539_AT1 and 4541_AT1 and 4711_AT1 and 4706_AT1 and 4712_AT1 and 4710_AT1 and 4715_AT1 and 4700_AT1 and 4713_AT1 and 4723_AT1 and 4714_AT1 and 4707_AT1 and 4718_AT1 and 4694_AT1 and 4696_AT1 and 4726_AT1 and 4725_AT1 and 4716_AT1 and 374291_AT1 and 51079_AT1 and 4722_AT1 and 4536_AT1 and 7991_AT2 and 4704_AT1 and 4705_AT1 and 4537_AT1 and 4731_AT2 and 4695_AT1 and 55967_AT1 and 4729_AT1 and 4709_AT1 and 4697_AT1 and 4728_AT1 and 4708_AT1 and 4720_AT1) or (4725_AT1 and 4716_AT1 and 4694_AT1 and 4707_AT1 and 4718_AT1 and 4696_AT1 and 4726_AT1 and 7991_AT2 and 4704_AT1 and 4705_AT1 and 4537_AT1 and 374291_AT1 and 51079_AT1 and 4722_AT1 and 4536_AT1 and 4709_AT1 and 4697_AT1 and 55967_AT1 and 4695_AT1 and 4729_AT1 and 4720_AT1 and 4708_AT1 and 4728_AT1 and 4719_AT1 and 4698_AT1 and 4701_AT1 and 4724_AT1 and 4538_AT1 and 4717_AT1 and 126328_AT1 and 4540_AT1 and 4715_AT1 and 4710_AT1 and 4700_AT1 and 4535_AT1 and 4702_AT1 and 4539_AT1 and 4711_AT1 and 4706_AT1 and 4541_AT1 and 4712_AT1 and 4731_AT1 and 4714_AT1 and 4713_AT1 and 4723_AT1) or (4723_AT1 and 4713_AT1 and 4714_AT1 and 4731_AT1 and 4712_AT1 and 4541_AT1 and 4711_AT1 and 4706_AT1 and 4535_AT1 and 4702_AT1 and 4539_AT1 and 4700_AT1 and 4715_AT1 and 4710_AT1 and 4540_AT1 and 4717_AT1 and 126328_AT1 and 4538_AT1 and 4701_AT1 and 4724_AT1 and 4698_AT1 and 4719_AT1 and 4728_AT1 and 4720_AT1 and 4708_AT1 and 4729_AT1 and 4695_AT1 and 55967_AT1 and 4697_AT1 and 4709_AT1 and 4536_AT1 and 4722_AT1 and 51079_AT1 and 7991_AT1 and 374291_AT1 and 4537_AT1 and 4704_AT1 and 4705_AT1 and 4726_AT1 and 4696_AT1 and 4694_AT1 and 4707_AT1 and 4718_AT1 and 4716_AT1 and 4725_AT1) or (4716_AT1 and 4725_AT1 and 4726_AT1 and 4696_AT1 and 4694_AT1 and 4718_AT1 and 4707_AT1 and 4537_AT1 and 4731_AT2 and 4705_AT1 and 4704_AT1 and 4722_AT1 and 4536_AT1 and 51079_AT1 and 7991_AT1 and 374291_AT1 and 4697_AT1 and 4709_AT1 and 4729_AT1 and 4695_AT1 and 55967_AT1 and 4708_AT1 and 4720_AT1 and 4728_AT1 and 4719_AT1 and 4701_AT1 and 4724_AT1 and 4698_AT1 and 4540_AT1 and 4717_AT1 and 126328_AT1 and 4538_AT1 and 4700_AT1 and 4715_AT1 and 4710_AT1 and 4712_AT1 and 4706_AT1 and 4541_AT1 and 4711_AT1 and 4702_AT1 and 4535_AT1 and 4539_AT1 and 4714_AT1 and 4723_AT1 and 4713_AT1) or (4711_AT1 and 4541_AT1 and 4706_AT1 and 4731_AT1 and 4535_AT1 and 4539_AT1 and 4702_AT1 and 4700_AT1 and 4710_AT1 and 4715_AT1 and 4723_AT1 and 4713_AT1 and 4714_AT1 and 4719_AT1 and 4717_AT1 and 126328_AT1 and 4540_AT1 and 4538_AT1 and 4724_AT1 and 4701_AT1 and 4698_AT1 and 4729_AT1 and 55967_AT1 and 4695_AT1 and 4697_AT1 and 4709_AT1 and 4728_AT1 and 4708_AT1 and 4720_AT1 and 4696_AT1 and 4726_AT1 and 4718_AT1 and 4707_AT1 and 4694_AT1 and 4725_AT1 and 4716_AT1 and 4712_AT2 and 4536_AT1 and 4722_AT1 and 7991_AT1 and 374291_AT1 and 51079_AT1 and 4705_AT1 and 4704_AT1 and 4537_AT1)",
"subsystem":"Oxidative Phosphorylation",
"notes":{
"original_bigg_ids":[
"NADH2_u10m"
]
},
"annotation":{
"bigg.reaction":[
"NADH2_u10m"
],
"metanetx.reaction":[
"MNXR101867"
],
"sbo":"SBO:0000185"
}
},
{
"id":"NADHtpu",
"name":"NADH transporter, peroxisome",
"metabolites":{
"nadh_c":-1.0,
"nadh_x":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Peroxisomal",
"notes":{
"original_bigg_ids":[
"NADHtpu"
]
},
"annotation":{
"bigg.reaction":[
"NADHtpu"
],
"metanetx.reaction":[
"MNXR101881"
],
"sbo":"SBO:0000185"
}
},
{
"id":"NADHtru",
"name":"NADH transporter, endoplasmic reticulum",
"metabolites":{
"nadh_c":-1.0,
"nadh_r":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Transport, Endoplasmic Reticular",
"notes":{
"original_bigg_ids":[
"NADHtru"
]
},
"annotation":{
"bigg.reaction":[
"NADHtru"
],
"metanetx.reaction":[
"MNXR101881"
],
"sbo":"SBO:0000185"
}
},
{
"id":"NADK",
"name":"NAD kinase",
"metabolites":{
"adp_c":1.0,
"atp_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadp_c":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"65220_AT1",
"subsystem":"NAD Metabolism",
"notes":{
"original_bigg_ids":[
"NADK"
]
},
"annotation":{
"bigg.reaction":[
"NADK"
],
"biocyc":[
"META:NAD-KIN-RXN"
],
"ec-code":[
"2.7.1.23"
],
"kegg.reaction":[
"R00104"
],
"metanetx.reaction":[
"MNXR101882"
],
"reactome.reaction":[
"R-DDI-197198",
"R-OSA-197198",
"R-TGU-197198",
"R-XTR-197198",
"R-SCE-197198",
"R-SPO-197198",
"R-DRE-197198",
"R-GGA-197198",
"R-ATH-197198",
"R-CFA-197198",
"R-DME-197198",
"R-MMU-197198",
"R-HSA-197198",
"R-RNO-197198",
"R-BTA-197198"
],
"rhea":[
"18631",
"18632",
"18629",
"18630"
],
"sabiork":[
"47"
],
"sbo":"SBO:0000176",
"seed.reaction":[
"rxn00077"
]
}
},
{
"id":"NADN",
"name":"NAD nucleosidase",
"metabolites":{
"adprib_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"ncam_c":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"NAD Metabolism",
"notes":{
"original_bigg_ids":[
"NADN"
]
},
"annotation":{
"bigg.reaction":[
"NADN"
],
"biocyc":[
"META:NADNUCLEOSID-RXN",
"META:RXN-13859"
],
"ec-code":[
"3.5.1.-",
"3.2.2.5",
"3.2.2.6"
],
"kegg.reaction":[
"R00102"
],
"metanetx.reaction":[
"MNXR101888"
],
"reactome.reaction":[
"R-BTA-8870346",
"R-RNO-8938076",
"R-BTA-8938076",
"R-TGU-8938076",
"R-CFA-8870346",
"R-SSC-8938076",
"R-XTR-8870346",
"R-HSA-8870346",
"R-GGA-8870346",
"R-HSA-8938076",
"R-GGA-8938076",
"R-MMU-8938076",
"R-RNO-8870346",
"R-CFA-8938076",
"R-MMU-8870346",
"R-XTR-8938076",
"R-TGU-8870346",
"R-SSC-8870346"
],
"rhea":[
"16304",
"16302",
"16303",
"16301"
],
"sabiork":[
"683"
],
"sbo":"SBO:0000176",
"seed.reaction":[
"rxn00075",
"rxn13106",
"rxn14307"
]
}
},
{
"id":"NADNe",
"name":"NAD nucleosidase,extracellular",
"metabolites":{
"adprib_e":1.0,
"h2o_e":-1.0,
"h_e":1.0,
"nad_e":-1.0,
"ncam_e":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"952_AT1",
"subsystem":"NAD Metabolism",
"notes":{
"original_bigg_ids":[
"NADNe"
]
},
"annotation":{
"bigg.reaction":[
"NADNe"
],
"biocyc":[
"META:NADNUCLEOSID-RXN",
"META:RXN-13859"
],
"ec-code":[
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"3.2.2.5",
"3.2.2.6"
],
"kegg.reaction":[
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],
"metanetx.reaction":[
"MNXR101888"
],
"reactome.reaction":[
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"R-RNO-8938076",
"R-BTA-8938076",
"R-TGU-8938076",
"R-CFA-8870346",
"R-SSC-8938076",
"R-XTR-8870346",
"R-HSA-8870346",
"R-GGA-8870346",
"R-HSA-8938076",
"R-GGA-8938076",
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"sbo":"SBO:0000176"
}
},
{
"id":"P4502E1",
"name":"Cytochrome P450 2E1",
"metabolites":{
"24nph_c":1.0,
"4nph_c":-1.0,
"h2o_c":1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0,
"o2_c":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"1571_AT1",
"subsystem":"CYP Metabolism",
"notes":{
"original_bigg_ids":[
"P4502E1"
]
},
"annotation":{
"bigg.reaction":[
"P4502E1"
],
"metanetx.reaction":[
"MNXR102281"
],
"sbo":"SBO:0000176"
}
},
{
"id":"PI3P5K",
"name":"Phosphatidylinositol 3-phosphate 5-kinase",
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"atp_c":-1.0,
"h_c":1.0,
"pail35p_hs_c":1.0,
"pail3p_hs_c":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"8394_AT1 or 8395_AT1 or 23396_AT1",
"subsystem":"Inositol Phosphate Metabolism",
"notes":{
"original_bigg_ids":[
"PI3P5K"
]
},
"annotation":{
"bigg.reaction":[
"PI3P5K"
],
"metanetx.reaction":[
"MNXR102709"
],
"sbo":"SBO:0000176"
}
},
{
"id":"PI3PP",
"name":"Phosphatidylinositol-3-phosphate 3-phosphatase",
"metabolites":{
"h2o_c":-1.0,
"pail3p_hs_c":-1.0,
"pail_hs_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"8897_AT2 or 8897_AT1 or 8897_AT3",
"subsystem":"Inositol Phosphate Metabolism",
"notes":{
"original_bigg_ids":[
"PI3PP"
]
},
"annotation":{
"bigg.reaction":[
"PI3PP"
],
"metanetx.reaction":[
"MNXR102704"
],
"sbo":"SBO:0000176"
}
},
{
"id":"PI4PP",
"name":"Phosphatidylinositol-4-phosphate 4-phosphatase",
"metabolites":{
"h2o_c":-1.0,
"pail4p_hs_c":-1.0,
"pail_hs_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Inositol Phosphate Metabolism",
"notes":{
"original_bigg_ids":[
"PI4PP"
]
},
"annotation":{
"bigg.reaction":[
"PI4PP"
],
"metanetx.reaction":[
"MNXR102763"
],
"sbo":"SBO:0000176"
}
},
{
"id":"PI5P3K",
"name":"Phosphatidylinositol-5-phosphate 3-kinase",
"metabolites":{
"adp_c":1.0,
"atp_c":-1.0,
"h_c":1.0,
"pail35p_hs_c":1.0,
"pail5p_hs_c":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"(5293_AT1 and 5296_AT1) or (5295_AT2 and 5293_AT1) or (5290_AT1 and 5295_AT1) or (5291_AT1 and 5295_AT3) or (5291_AT1 and 5295_AT2) or (5294_AT1 and 23533_AT1) or (5290_AT1 and 8503_AT1) or (5290_AT1 and 5295_AT2) or (5291_AT1 and 5296_AT1) or 5288_AT1 or (5295_AT1 and 5291_AT1) or (8503_AT1 and 5293_AT1) or (8503_AT1 and 5291_AT1) or 5289_AT1 or 5287_AT1 or (5290_AT1 and 5296_AT1) or 5286_AT1 or (5294_AT1 and 10870_AT1) or (5295_AT1 and 5293_AT1) or (5290_AT1 and 5295_AT3) or (5293_AT1 and 5295_AT3)",
"subsystem":"Inositol Phosphate Metabolism",
"notes":{
"original_bigg_ids":[
"PI5P3K"
]
},
"annotation":{
"bigg.reaction":[
"PI5P3K"
],
"metanetx.reaction":[
"MNXR102816"
],
"sbo":"SBO:0000176"
}
},
{
"id":"PI5P3Ker",
"name":"Phosphatidylinositol-5-phosphate 3-kinase, endoplasmic reticulum",
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"adp_r":1.0,
"atp_r":-1.0,
"h_r":1.0,
"pail35p_hs_r":1.0,
"pail5p_hs_r":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"5287_AT1",
"subsystem":"Inositol Phosphate Metabolism",
"notes":{
"original_bigg_ids":[
"PI5P3Ker"
]
},
"annotation":{
"bigg.reaction":[
"PI5P3Ker"
],
"metanetx.reaction":[
"MNXR102816"
],
"sbo":"SBO:0000176"
}
},
{
"id":"PI5P4K",
"name":"Phosphatidylinositol-5-phosphate 4-kinase",
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"atp_c":-1.0,
"h_c":1.0,
"pail45p_hs_c":1.0,
"pail5p_hs_c":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"55361_AT1 or 5298_AT1 or 5297_AT1",
"subsystem":"Inositol Phosphate Metabolism",
"notes":{
"original_bigg_ids":[
"PI5P4K"
]
},
"annotation":{
"bigg.reaction":[
"PI5P4K"
],
"metanetx.reaction":[
"MNXR102818"
],
"sbo":"SBO:0000176"
}
},
{
"id":"PI5P4Kn",
"name":"Phosphatidylinositol-5-phosphate 4-kinase, nuclear",
"metabolites":{
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"atp_n":-1.0,
"h_n":1.0,
"pail45p_hs_n":1.0,
"pail5p_hs_n":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Inositol Phosphate Metabolism",
"notes":{
"original_bigg_ids":[
"PI5P4Kn"
]
},
"annotation":{
"bigg.reaction":[
"PI5P4Kn"
],
"metanetx.reaction":[
"MNXR102818"
],
"sbo":"SBO:0000176"
}
},
{
"id":"PIACGT",
"name":"Phosphatidylinositol N-acetylglucosaminyltransferase",
"metabolites":{
"acgpail_hs_c":1.0,
"h_c":1.0,
"pail_hs_c":-1.0,
"uacgam_c":-1.0,
"udp_c":1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"(5283_AT1 and 51227_AT2 and 9091_AT1 and 5277_AT2 and 8818_AT2 and 5279_AT2) or (5277_AT1 and 5279_AT2 and 8818_AT2 and 5283_AT1 and 51227_AT1 and 9091_AT2) or (5277_AT1 and 5279_AT1 and 9091_AT1 and 8818_AT1 and 51227_AT2 and 5283_AT1) or (8818_AT1 and 5279_AT2 and 9091_AT2 and 5277_AT3 and 5283_AT1 and 51227_AT2) or (5283_AT1 and 9091_AT2 and 51227_AT2 and 8818_AT1 and 5279_AT1 and 5277_AT2) or (51227_AT2 and 5283_AT1 and 5279_AT2 and 8818_AT1 and 5277_AT1 and 9091_AT1) or (5279_AT1 and 8818_AT1 and 5277_AT3 and 9091_AT2 and 5283_AT1 and 51227_AT2) or (5283_AT1 and 51227_AT1 and 9091_AT2 and 5279_AT2 and 8818_AT2 and 5277_AT2) or (5283_AT1 and 9091_AT2 and 51227_AT3 and 5279_AT2 and 8818_AT2 and 5277_AT2) or (5283_AT1 and 9091_AT2 and 51227_AT2 and 8818_AT2 and 5279_AT1 and 5277_AT2) or (5283_AT1 and 9091_AT2 and 51227_AT1 and 8818_AT1 and 5279_AT2 and 5277_AT1) or (5277_AT1 and 8818_AT2 and 5279_AT2 and 5283_AT1 and 51227_AT3 and 9091_AT2) or (5283_AT1 and 51227_AT2 and 8818_AT2 and 5279_AT2 and 9091_AT1 and 5277_AT1) or (5279_AT2 and 8818_AT2 and 5277_AT2 and 9091_AT1 and 51227_AT3 and 5283_AT1) or (51227_AT1 and 5277_AT3 and 5283_AT1 and 9091_AT1 and 5279_AT2 and 8818_AT2) or (9091_AT1 and 5279_AT1 and 8818_AT1 and 5277_AT3 and 5283_AT1 and 51227_AT2) or (51227_AT3 and 5283_AT1 and 5277_AT3 and 8818_AT2 and 5279_AT1 and 9091_AT1) or (8818_AT1 and 5277_AT1 and 5279_AT1 and 9091_AT2 and 5283_AT1 and 51227_AT3) or (51227_AT2 and 5283_AT1 and 9091_AT2 and 5279_AT1 and 5277_AT1 and 8818_AT1) or (51227_AT1 and 5283_AT1 and 5277_AT3 and 9091_AT2 and 5279_AT1 and 8818_AT2) or (5277_AT3 and 5283_AT1 and 51227_AT3 and 5279_AT1 and 9091_AT1 and 8818_AT1) or (51227_AT3 and 5283_AT1 and 9091_AT1 and 5277_AT1 and 8818_AT2 and 5279_AT2) or (5283_AT1 and 51227_AT3 and 9091_AT2 and 8818_AT2 and 5277_AT1 and 5279_AT1) or (51227_AT2 and 5283_AT1 and 9091_AT2 and 5277_AT3 and 5279_AT2 and 8818_AT2) or (8818_AT2 and 5279_AT1 and 5283_AT1 and 5277_AT3 and 9091_AT2 and 51227_AT3) or (5277_AT1 and 5279_AT2 and 8818_AT1 and 9091_AT2 and 5283_AT1 and 51227_AT2) or (9091_AT1 and 8818_AT2 and 5279_AT2 and 5277_AT3 and 5283_AT1 and 51227_AT2) or (51227_AT3 and 5283_AT1 and 8818_AT1 and 5279_AT1 and 5277_AT1 and 9091_AT1) or (5279_AT2 and 8818_AT1 and 5277_AT1 and 9091_AT2 and 51227_AT3 and 5283_AT1) or (5277_AT3 and 5283_AT1 and 9091_AT2 and 51227_AT1 and 5279_AT1 and 8818_AT1) or (5277_AT3 and 5283_AT1 and 51227_AT2 and 9091_AT1 and 5279_AT1 and 8818_AT2) or (8818_AT1 and 5279_AT1 and 5277_AT2 and 9091_AT2 and 5283_AT1 and 51227_AT3) or (5277_AT2 and 9091_AT1 and 5279_AT1 and 8818_AT1 and 51227_AT2 and 5283_AT1) or (51227_AT3 and 5283_AT1 and 5279_AT2 and 8818_AT1 and 9091_AT1 and 5277_AT1) or (5277_AT3 and 9091_AT2 and 5283_AT1 and 51227_AT2 and 5279_AT1 and 8818_AT2) or (5283_AT1 and 9091_AT2 and 51227_AT1 and 5277_AT2 and 5279_AT1 and 8818_AT2) or (8818_AT2 and 9091_AT1 and 5279_AT1 and 5277_AT2 and 51227_AT1 and 5283_AT1) or (5277_AT2 and 9091_AT1 and 5279_AT2 and 8818_AT1 and 5283_AT1 and 51227_AT1) or (8818_AT2 and 9091_AT1 and 5279_AT1 and 5277_AT1 and 51227_AT1 and 5283_AT1) or (5277_AT1 and 5279_AT2 and 8818_AT2 and 51227_AT2 and 9091_AT2 and 5283_AT1) or (8818_AT1 and 5279_AT2 and 5277_AT2 and 9091_AT1 and 51227_AT2 and 5283_AT1) or (5277_AT3 and 5283_AT1 and 51227_AT1 and 8818_AT2 and 9091_AT1 and 5279_AT1) or (9091_AT2 and 51227_AT1 and 5283_AT1 and 5277_AT2 and 5279_AT2 and 8818_AT1) or (5279_AT2 and 8818_AT2 and 9091_AT1 and 5277_AT1 and 5283_AT1 and 51227_AT1) or (5277_AT3 and 51227_AT1 and 5283_AT1 and 9091_AT2 and 5279_AT2 and 8818_AT2) or (5283_AT1 and 9091_AT2 and 51227_AT3 and 5277_AT3 and 8818_AT2 and 5279_AT2) or (5277_AT3 and 5283_AT1 and 51227_AT2 and 9091_AT1 and 5279_AT2 and 8818_AT1) or (8818_AT1 and 5279_AT2 and 9091_AT1 and 5277_AT2 and 51227_AT3 and 5283_AT1) or (5277_AT1 and 5279_AT1 and 8818_AT2 and 9091_AT2 and 5283_AT1 and 51227_AT2) or (8818_AT1 and 9091_AT1 and 5279_AT1 and 51227_AT1 and 5283_AT1 and 5277_AT3) or (5283_AT1 and 51227_AT3 and 9091_AT2 and 5277_AT3 and 8818_AT1 and 5279_AT1) or (9091_AT1 and 8818_AT1 and 5279_AT2 and 51227_AT1 and 5277_AT3 and 5283_AT1) or (51227_AT1 and 5283_AT1 and 9091_AT2 and 8818_AT2 and 5277_AT1 and 5279_AT1) or (5279_AT1 and 5277_AT1 and 9091_AT1 and 8818_AT2 and 5283_AT1 and 51227_AT3) or (8818_AT1 and 5279_AT1 and 5277_AT2 and 9091_AT2 and 5283_AT1 and 51227_AT1) or (5283_AT1 and 51227_AT3 and 5277_AT2 and 9091_AT1 and 5279_AT1 and 8818_AT1) or (5283_AT1 and 51227_AT1 and 8818_AT1 and 5277_AT1 and 5279_AT1 and 9091_AT1) or (9091_AT2 and 5277_AT3 and 51227_AT1 and 5283_AT1 and 8818_AT1 and 5279_AT2) or (51227_AT3 and 5283_AT1 and 9091_AT2 and 5277_AT2 and 8818_AT1 and 5279_AT2) or (5277_AT2 and 9091_AT1 and 5279_AT1 and 8818_AT2 and 51227_AT3 and 5283_AT1) or (5283_AT1 and 51227_AT1 and 5277_AT2 and 9091_AT1 and 5279_AT1 and 8818_AT1) or (8818_AT1 and 9091_AT1 and 5279_AT1 and 5277_AT2 and 5283_AT1 and 51227_AT2) or (5277_AT2 and 5279_AT2 and 8818_AT1 and 51227_AT2 and 5283_AT1 and 9091_AT2) or (5279_AT2 and 8818_AT1 and 9091_AT1 and 5277_AT3 and 5283_AT1 and 51227_AT3) or (5283_AT1 and 5277_AT3 and 51227_AT3 and 5279_AT2 and 8818_AT2 and 9091_AT1) or (5279_AT2 and 8818_AT1 and 51227_AT3 and 5277_AT3 and 9091_AT2 and 5283_AT1) or (5279_AT1 and 5277_AT2 and 8818_AT2 and 51227_AT3 and 5283_AT1 and 9091_AT2) or (8818_AT1 and 5277_AT1 and 5279_AT1 and 9091_AT2 and 51227_AT1 and 5283_AT1) or (9091_AT1 and 5277_AT1 and 8818_AT1 and 5279_AT2 and 5283_AT1 and 51227_AT1) or (5283_AT1 and 51227_AT2 and 5279_AT1 and 9091_AT1 and 5277_AT1 and 8818_AT2) or (5277_AT2 and 8818_AT2 and 5279_AT2 and 9091_AT2 and 5283_AT1 and 51227_AT2) or (51227_AT1 and 5283_AT1 and 5279_AT2 and 8818_AT2 and 5277_AT2 and 9091_AT1)",
"subsystem":"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis",
"notes":{
"original_bigg_ids":[
"PIACGT"
]
},
"annotation":{
"bigg.reaction":[
"PIACGT"
],
"metanetx.reaction":[
"MNXR102820"
],
"sbo":"SBO:0000176"
}
},
{
"id":"PIK3",
"name":"Phosphatidylinositol 3-kinase",
"metabolites":{
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"atp_c":-1.0,
"h_c":1.0,
"pail3p_hs_c":1.0,
"pail_hs_c":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"(5296_AT1 and 5293_AT1) or (5296_AT1 and 5291_AT1) or (5290_AT1 and 5295_AT1) or (8503_AT1 and 5290_AT1) or (23533_AT1 and 5294_AT1) or (5295_AT2 and 5291_AT1) or (5295_AT3 and 5291_AT1) or (5295_AT3 and 5290_AT1) or (5295_AT2 and 5293_AT1) or (5296_AT1 and 5290_AT1) or 5287_AT1 or (10870_AT1 and 5294_AT1) or 5286_AT1 or (5291_AT1 and 8503_AT1) or (5293_AT1 and 8503_AT1) or 5289_AT1 or (5295_AT1 and 5291_AT1) or 5288_AT1 or (5295_AT3 and 5293_AT1) or (5290_AT1 and 5295_AT2) or (5293_AT1 and 5295_AT1)",
"subsystem":"Inositol Phosphate Metabolism",
"notes":{
"original_bigg_ids":[
"PIK3"
]
},
"annotation":{
"bigg.reaction":[
"PIK3"
],
"metanetx.reaction":[
"MNXR102823"
],
"sbo":"SBO:0000176"
}
},
{
"id":"PIK3er",
"name":"Phosphatidylinositol 3-kinase, endoplasmic reticulum",
"metabolites":{
"adp_r":1.0,
"atp_r":-1.0,
"h_r":1.0,
"pail3p_hs_r":1.0,
"pail_hs_r":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"5287_AT1",
"subsystem":"Inositol Phosphate Metabolism",
"notes":{
"original_bigg_ids":[
"PIK3er"
]
},
"annotation":{
"bigg.reaction":[
"PIK3er"
],
"metanetx.reaction":[
"MNXR102823"
],
"sbo":"SBO:0000176"
}
},
{
"id":"PIK3n",
"name":"Phosphatidylinositol 3-kinase, nuclear",
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"atp_n":-1.0,
"h_n":1.0,
"pail3p_hs_n":1.0,
"pail_hs_n":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Inositol Phosphate Metabolism",
"notes":{
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"PIK3n"
]
},
"annotation":{
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"PIK3n"
],
"metanetx.reaction":[
"MNXR102823"
],
"sbo":"SBO:0000176"
}
},
{
"id":"PIK4",
"name":"Phosphatidylinositol 4-kinase",
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"atp_c":-1.0,
"h_c":1.0,
"pail4p_hs_c":1.0,
"pail_hs_c":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"55361_AT1 or 5297_AT1 or 5298_AT1",
"subsystem":"Glycerophospholipid Metabolism",
"notes":{
"original_bigg_ids":[
"PIK4"
]
},
"annotation":{
"bigg.reaction":[
"PIK4"
],
"metanetx.reaction":[
"MNXR102825"
],
"sbo":"SBO:0000176"
}
},
{
"id":"PIK4n",
"name":"Phosphatidylinositol 4-kinase, nuclear",
"metabolites":{
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"atp_n":-1.0,
"h_n":1.0,
"pail4p_hs_n":1.0,
"pail_hs_n":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Inositol Phosphate Metabolism",
"notes":{
"original_bigg_ids":[
"PIK4n"
]
},
"annotation":{
"bigg.reaction":[
"PIK4n"
],
"metanetx.reaction":[
"MNXR102825"
],
"sbo":"SBO:0000176"
}
},
{
"id":"PIK5",
"name":"Phosphatidylinositol 5-kinase",
"metabolites":{
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"atp_c":-1.0,
"h_c":1.0,
"pail5p_hs_c":1.0,
"pail_hs_c":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"23396_AT1 or 8394_AT1 or 8395_AT1",
"subsystem":"Inositol Phosphate Metabolism",
"notes":{
"original_bigg_ids":[
"PIK5"
]
},
"annotation":{
"bigg.reaction":[
"PIK5"
],
"metanetx.reaction":[
"MNXR102844"
],
"sbo":"SBO:0000176"
}
},
{
"id":"PIK5n",
"name":"Phosphatidylinositol 5-kinase, nuclear",
"metabolites":{
"adp_n":1.0,
"atp_n":-1.0,
"h_n":1.0,
"pail5p_hs_n":1.0,
"pail_hs_n":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Inositol Phosphate Metabolism",
"notes":{
"original_bigg_ids":[
"PIK5n"
]
},
"annotation":{
"bigg.reaction":[
"PIK5n"
],
"metanetx.reaction":[
"MNXR102844"
],
"sbo":"SBO:0000176"
}
},
{
"id":"PI45P3K",
"name":"Phosphatidylinositol 4,5-bisphosphate 3-kinase",
"metabolites":{
"adp_c":1.0,
"atp_c":-1.0,
"h_c":1.0,
"pail345p_hs_c":1.0,
"pail45p_hs_c":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"(5290_AT1 and 5295_AT1) or (5293_AT1 and 5295_AT2) or (5290_AT1 and 5295_AT2) or (5294_AT1 and 23533_AT1) or (5290_AT1 and 8503_AT1) or (5296_AT1 and 5293_AT1) or (5296_AT1 and 5290_AT1) or (5291_AT1 and 5295_AT1) or (5295_AT2 and 5291_AT1) or (10870_AT1 and 5294_AT1) or (8503_AT1 and 5291_AT1) or (5295_AT1 and 5293_AT1) or (5293_AT1 and 5295_AT3) or (5293_AT1 and 8503_AT1) or (5291_AT1 and 5295_AT3) or (5295_AT3 and 5290_AT1) or (5291_AT1 and 5296_AT1)",
"subsystem":"Inositol Phosphate Metabolism",
"notes":{
"original_bigg_ids":[
"PI45P3K"
]
},
"annotation":{
"bigg.reaction":[
"PI45P3K"
],
"metanetx.reaction":[
"MNXR102714"
],
"sbo":"SBO:0000176"
}
},
{
"id":"PI45P3Kn",
"name":"Phosphatidylinositol 4,5-bisphosphate 3-kinase, nuclear",
"metabolites":{
"adp_n":1.0,
"atp_n":-1.0,
"h_n":1.0,
"pail345p_hs_n":1.0,
"pail45p_hs_n":-1.0
},
"lower_bound":0.0,
"upper_bound":999999.0,
"gene_reaction_rule":"",
"subsystem":"Inositol Phosphate Metabolism",
"notes":{
"original_bigg_ids":[
"PI45P3Kn"
]
},
"annotation":{
"bigg.reaction":[
"PI45P3Kn"
],
"metanetx.reaction":[
"MNXR102714"
],
"sbo":"SBO:0000176"
}
},
{
"id":"PI45P4P",
"name":"Phosphatidylinositol-4,5-bisphosphate 4-phosphatase",
"metabolites":{
"h2o_c":-1.0,
"pail45p_hs_c":-1.0,
"pail5p_hs_c":1.0,
"pi_c":1.0
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{
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}
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"PARK14",
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"NBIA2A",
"GVI",
"NBIA2",
"IPLA2-VIA",
"iPLA2",
"INAD1",
"iPLA2beta"
],
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}
},
{
"id":"30814_AT1",
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},
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}
},
{
"id":"50940_AT1",
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},
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"CCDS46459.1",
"CCDS33334.1"
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}
},
{
"id":"6487_AT4",
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},
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}
},
{
"id":"5322_AT1",
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},
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],
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"hVPLA(2)",
"FRFB"
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}
},
{
"id":"64600_AT1",
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},
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}
},
{
"id":"6487_AT9",
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},
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}
},
{
"id":"5136_AT1",
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},
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"HCAM1",
"CAM-PDE-1A"
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}
},
{
"id":"6487_AT3",
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},
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"CCDS493.1",
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}
},
{
"id":"5142_AT1",
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},
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"CCDS72802.1",
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"CCDS30743.1"
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],
"omim":[
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],
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}
},
{
"id":"81579_AT1",
"name":"PLA2G12A",
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"81579.1"
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},
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],
"omim":[
"611652"
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"GXII"
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}
},
{
"id":"26279_AT1",
"name":"PLA2G2D",
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"26279.1"
]
},
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"CCDS203.1"
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],
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"PLA2IID",
"sPLA2-IID"
],
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}
},
{
"id":"6487_AT10",
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},
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"CCDS492.1",
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"ST3N"
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}
},
{
"id":"5141_AT1",
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},
"annotation":{
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"CCDS58649.1",
"CCDS12238.1",
"CCDS45962.1"
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}
},
{
"id":"6487_AT8",
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},
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},
{
"id":"5151_AT3",
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},
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},
{
"id":"5144_AT1",
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},
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"CCDS56373.1",
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}
},
{
"id":"5319_AT1",
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},
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}
},
{
"id":"6487_AT1",
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},
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}
},
{
"id":"8399_AT1",
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},
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"GXPLA2"
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}
},
{
"id":"9789_AT1",
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},
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}
},
{
"id":"5153_AT1",
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},
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"PDES1B"
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}
},
{
"id":"6487_AT7",
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},
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}
},
{
"id":"8654_AT3",
"name":"PDE5A",
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},
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"PDE5"
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}
},
{
"id":"28972_AT1",
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},
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"HSPC033"
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}
},
{
"id":"6487_AT2",
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},
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},
{
"id":"6480_AT3",
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},
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},
{
"id":"60559_AT1",
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},
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"SPC22/23",
"PRO3567",
"YLR066W"
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}
},
{
"id":"5152_AT10",
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},
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},
{
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},
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},
{
"id":"90701_AT1",
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},
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"SPC21"
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}
},
{
"id":"6480_AT2",
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},
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},
{
"id":"5152_AT3",
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},
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}
},
{
"id":"10090_AT1",
"name":"UST",
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},
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}
},
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"omim":[
"191290"
],
"refseq_name":[
"TH"
],
"refseq_synonym":[
"TYH",
"DYT14",
"DYT5b"
],
"sbo":"SBO:0000243"
}
},
{
"id":"7054_AT2",
"name":"TH",
"notes":{
"original_bigg_ids":[
"7054.2"
]
},
"annotation":{
"ccds":[
"CCDS31338.1",
"CCDS7730.1",
"CCDS7731.1"
],
"ncbigene":[
"7054"
],
"ncbigi":[
"88900501",
"88900503",
"88900505",
"767966439"
],
"omim":[
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],
"refseq_name":[
"TH"
],
"refseq_synonym":[
"TYH",
"DYT14",
"DYT5b"
],
"sbo":"SBO:0000243"
}
},
{
"id":"7054_AT3",
"name":"TH",
"notes":{
"original_bigg_ids":[
"7054.3"
]
},
"annotation":{
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"CCDS7730.1",
"CCDS7731.1"
],
"ncbigene":[
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],
"ncbigi":[
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"88900505",
"767966439"
],
"omim":[
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],
"refseq_name":[
"TH"
],
"refseq_synonym":[
"TYH",
"DYT14",
"DYT5b"
],
"sbo":"SBO:0000243"
}
},
{
"id":"7306_AT1",
"name":"TYRP1",
"notes":{
"original_bigg_ids":[
"7306.1"
]
},
"annotation":{
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"CCDS34990.1"
],
"hprd":[
"00283"
],
"ncbigene":[
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],
"omim":[
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],
"refseq_name":[
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],
"refseq_synonym":[
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"TYRP",
"CAS2",
"CATB",
"b-PROTEIN",
"GP75",
"TRP",
"OCA3"
],
"sbo":"SBO:0000243"
}
},
{
"id":"2582_AT1",
"name":"GALE",
"notes":{
"original_bigg_ids":[
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]
},
"annotation":{
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],
"ncbigene":[
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],
"omim":[
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],
"refseq_name":[
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],
"refseq_synonym":[
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],
"sbo":"SBO:0000243"
}
},
{
"id":"2582_AT2",
"name":"GALE",
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]
},
"annotation":{
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],
"ncbigene":[
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],
"omim":[
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],
"refseq_name":[
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],
"refseq_synonym":[
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],
"sbo":"SBO:0000243"
}
}
],
"id":"RECON1",
"compartments":{
"c":"cytosol",
"e":"extracellular space",
"g":"golgi apparatus",
"l":"lysosome",
"m":"mitochondria",
"n":"nucleus",
"r":"endoplasmic reticulum",
"x":"peroxisome/glyoxysome"
},
"version":"1"
}